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FOLH1 (folate hydrolase (prostate-specific membrane antigen) 1)

Identity

Other namesFGCP
FOLH
GCP2
GCPII
NAALAD1
NAALAdase
PSM
PSMA
mGCP
HGNC (Hugo) FOLH1
LocusID (NCBI) 2346
Location 11p11.12
Location_base_pair Starts at 49168187 and ends at 49230222 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FOLH1   3788
Cards
Entrez_Gene (NCBI)FOLH1  2346  folate hydrolase (prostate-specific membrane antigen) 1
GeneCards (Weizmann)FOLH1
Ensembl (Hinxton)ENSG00000086205 [Gene_View]  chr11:49168187-49230222 [Contig_View]  FOLH1 [Vega]
AceView (NCBI)FOLH1
Genatlas (Paris)FOLH1
WikiGenes2346
SOURCE (Princeton)NM_001014986 NM_001193471 NM_001193472 NM_001193473 NM_004476
Genomic and cartography
GoldenPath (UCSC)FOLH1  -  11p11.12   chr11:49168187-49230222 -  11p11.12   [Description]    (hg19-Feb_2009)
EnsemblFOLH1 - 11p11.12 [CytoView]
Mapping of homologs : NCBIFOLH1 [Mapview]
OMIM600934   
Gene and transcription
Genbank (Entrez)AF176574 AF254357 AF254358 AJ007318 AK295368
RefSeq transcript (Entrez)NM_001014986 NM_001193471 NM_001193472 NM_001193473 NM_004476
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_029170 NT_009237 NW_001838022 NW_004929378
Consensus coding sequences : CCDS (NCBI)FOLH1
Cluster EST : UnigeneHs.654487 [ NCBI ]
CGAP (NCI)Hs.654487
Alternative Splicing : Fast-db (Paris)GSHG0005751
Alternative Splicing GalleryENSG00000086205
Gene ExpressionFOLH1 [ NCBI-GEO ]     FOLH1 [ SEEK ]   FOLH1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ04609 (Uniprot)
NextProtQ04609  [Medical]
With graphics : InterProQ04609
Splice isoforms : SwissVarQ04609 (Swissvar)
Catalytic activity : Enzyme3.4.17.21 [ Enzyme-Expasy ]   3.4.17.213.4.17.21 [ IntEnz-EBI ]   3.4.17.21 [ BRENDA ]   3.4.17.21 [ KEGG ]   
Domains : Interpro (EBI)Peptidase_M28    Protease-assoc_domain    TFR-like_dimer_dom   
Related proteins : CluSTrQ04609
Domain families : Pfam (Sanger)PA (PF02225)    Peptidase_M28 (PF04389)    TFR_dimer (PF04253)   
Domain families : Pfam (NCBI)pfam02225    pfam04389    pfam04253   
DMDM Disease mutations2346
Blocks (Seattle)Q04609
PDB (SRS)1Z8L    2C6C    2C6G    2C6P    2CIJ    2JBJ    2JBK    2OOT    2OR4    2PVV    2PVW    2XEF    2XEG    2XEI    2XEJ    3BHX    3BI0    3BI1    3BXM    3D7D    3D7F    3D7G    3D7H    3IWW    3RBU    3SJE    3SJF    3SJG    3SJX   
PDB (PDBSum)1Z8L    2C6C    2C6G    2C6P    2CIJ    2JBJ    2JBK    2OOT    2OR4    2PVV    2PVW    2XEF    2XEG    2XEI    2XEJ    3BHX    3BI0    3BI1    3BXM    3D7D    3D7F    3D7G    3D7H    3IWW    3RBU    3SJE    3SJF    3SJG    3SJX   
PDB (IMB)1Z8L    2C6C    2C6G    2C6P    2CIJ    2JBJ    2JBK    2OOT    2OR4    2PVV    2PVW    2XEF    2XEG    2XEI    2XEJ    3BHX    3BI0    3BI1    3BXM    3D7D    3D7F    3D7G    3D7H    3IWW    3RBU    3SJE    3SJF    3SJG    3SJX   
PDB (RSDB)1Z8L    2C6C    2C6G    2C6P    2CIJ    2JBJ    2JBK    2OOT    2OR4    2PVV    2PVW    2XEF    2XEG    2XEI    2XEJ    3BHX    3BI0    3BI1    3BXM    3D7D    3D7F    3D7G    3D7H    3IWW    3RBU    3SJE    3SJF    3SJG    3SJX   
Human Protein AtlasENSG00000086205
Peptide AtlasQ04609
HPRD02961
IPIIPI00028514   IPI01012792   IPI00216908   IPI00216910   IPI00944663   IPI00944595   IPI00973065   IPI00216907   IPI00956242   IPI01009620   IPI00979907   IPI00985121   IPI00982246   
Protein Interaction databases
DIP (DOE-UCLA)Q04609
IntAct (EBI)Q04609
FunCoupENSG00000086205
BioGRIDFOLH1
InParanoidQ04609
Interologous Interaction database Q04609
IntegromeDBFOLH1
STRING (EMBL)FOLH1
Ontologies - Pathways
Ontology : AmiGOcarboxypeptidase activity  nucleus  cytoplasm  integral to plasma membrane  proteolysis  folic acid-containing compound metabolic process  peptidase activity  metallopeptidase activity  membrane  dipeptidase activity  metal ion binding  
Ontology : EGO-EBIcarboxypeptidase activity  nucleus  cytoplasm  integral to plasma membrane  proteolysis  folic acid-containing compound metabolic process  peptidase activity  metallopeptidase activity  membrane  dipeptidase activity  metal ion binding  
Pathways : KEGGVitamin digestion and absorption   
REACTOMEFOLH1
Protein Interaction DatabaseFOLH1
Wikipedia pathwaysFOLH1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FOLH1
SNP (GeneSNP Utah)FOLH1
SNP : HGBaseFOLH1
Genetic variants : HAPMAPFOLH1
1000_GenomesFOLH1 
ICGC programENSG00000086205 
Somatic Mutations in Cancer : COSMICFOLH1 
CONAN: Copy Number AnalysisFOLH1 
Mutations and Diseases : HGMDFOLH1
OMIM600934   
GENETestsFOLH1
Disease Genetic AssociationFOLH1
Huge Navigator FOLH1 [HugePedia]  FOLH1 [HugeCancerGEM]
Genomic VariantsFOLH1  FOLH1 [DGVbeta]
Exome VariantFOLH1
dbVarFOLH1
ClinVarFOLH1
snp3D : Map Gene to Disease2346
General knowledge
Homologs : HomoloGeneFOLH1
Homology/Alignments : Family Browser (UCSC)FOLH1
Phylogenetic Trees/Animal Genes : TreeFamFOLH1
Chemical/Protein Interactions : CTD2346
Chemical/Pharm GKB GenePA28205
Clinical trialFOLH1
Cancer Resource (Charite)ENSG00000086205
Other databases
Probes
Litterature
PubMed128 Pubmed reference(s) in Entrez
CoreMineFOLH1
iHOPFOLH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Mar 31 09:25:25 CEST 2014

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