Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FOLH1B (folate hydrolase 1B)

Identity

Alias_namesFOLH2
FOLHP
folate hydrolase 2
Alias_symbol (synonym)PSMAL
Other aliasGCP3
GCPIII
PSM
PSMA-LIKE
HGNC (Hugo) FOLH1B
LocusID (NCBI) 219595
Atlas_Id 50977
Location 11q14.3  [Link to chromosome band 11q14]
Location_base_pair Starts at 89659297 and ends at 89698718 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FOLH1B   13636
Cards
Entrez_Gene (NCBI)FOLH1B  219595  folate hydrolase 1B
AliasesFOLH2; FOLHP; GCP3; GCPIII; 
PSM; PSMA-LIKE; PSMAL
GeneCards (Weizmann)FOLH1B
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr11:89659297-89698718 [Contig_View]  FOLH1B [Vega]
TCGA cBioPortalFOLH1B
AceView (NCBI)FOLH1B
Genatlas (Paris)FOLH1B
WikiGenes219595
SOURCE (Princeton)FOLH1B
Genetics Home Reference (NIH)FOLH1B
Genomic and cartography
GoldenPath hg38 (UCSC)FOLH1B  -     chr11:89659297-89698718 +  11q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOLH1B  -     11q14.3   [Description]    (hg19-Feb_2009)
GoldenPathFOLH1B - 11q14.3 [CytoView hg19]  FOLH1B - 11q14.3 [CytoView hg38]
Mapping of homologs : NCBIFOLH1B [Mapview hg19]  FOLH1B [Mapview hg38]
OMIM609020   
Gene and transcription
Genbank (Entrez)AF261715 AY544126
RefSeq transcript (Entrez)NM_153696
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOLH1B
Gene ExpressionFOLH1B [ NCBI-GEO ]   FOLH1B [ EBI - ARRAY_EXPRESS ]   FOLH1B [ SEEK ]   FOLH1B [ MEM ]
Gene Expression Viewer (FireBrowse)FOLH1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219595
GTEX Portal (Tissue expression)FOLH1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBA9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HBA9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HBA9
Splice isoforms : SwissVarQ9HBA9
Catalytic activity : Enzyme3.4.-.- [ Enzyme-Expasy ]   3.4.-.-3.4.-.- [ IntEnz-EBI ]   3.4.-.- [ BRENDA ]   3.4.-.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9HBA9
Domains : Interpro (EBI)Peptidase_M28    Peptidase_M28B    TFR-like_dimer_dom    TFR-like_dimer_dom_sf   
Domain families : Pfam (Sanger)Peptidase_M28 (PF04389)    TFR_dimer (PF04253)   
Domain families : Pfam (NCBI)pfam04389    pfam04253   
Conserved Domain (NCBI)FOLH1B
DMDM Disease mutations219595
Blocks (Seattle)FOLH1B
SuperfamilyQ9HBA9
Peptide AtlasQ9HBA9
HPRD07150
IPIIPI00176923   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBA9
IntAct (EBI)Q9HBA9
BioGRIDFOLH1B
STRING (EMBL)FOLH1B
ZODIACFOLH1B
Ontologies - Pathways
QuickGOQ9HBA9
Ontology : AmiGOcarboxypeptidase activity  metallocarboxypeptidase activity  cytoplasm  plasma membrane  plasma membrane  proteolysis  cellular amino acid biosynthetic process  dipeptidase activity  C-terminal protein deglutamylation  metal ion binding  extracellular exosome  
Ontology : EGO-EBIcarboxypeptidase activity  metallocarboxypeptidase activity  cytoplasm  plasma membrane  plasma membrane  proteolysis  cellular amino acid biosynthetic process  dipeptidase activity  C-terminal protein deglutamylation  metal ion binding  extracellular exosome  
NDEx NetworkFOLH1B
Atlas of Cancer Signalling NetworkFOLH1B
Wikipedia pathwaysFOLH1B
Orthology - Evolution
OrthoDB219595
Phylogenetic Trees/Animal Genes : TreeFamFOLH1B
HOGENOMQ9HBA9
Homologs : HomoloGeneFOLH1B
Homology/Alignments : Family Browser (UCSC)FOLH1B
Gene fusions - Rearrangements
Fusion : QuiverFOLH1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOLH1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOLH1B
dbVarFOLH1B
ClinVarFOLH1B
1000_GenomesFOLH1B 
Exome Variant ServerFOLH1B
Varsome BrowserFOLH1B
Genetic variants : HAPMAP219595
Genomic Variants (DGV)FOLH1B [DGVbeta]
DECIPHERFOLH1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOLH1B 
Mutations
ICGC Data PortalFOLH1B 
TCGA Data PortalFOLH1B 
Broad Tumor PortalFOLH1B
OASIS PortalFOLH1B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDFOLH1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOLH1B
DgiDB (Drug Gene Interaction Database)FOLH1B
DoCM (Curated mutations)FOLH1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOLH1B (select a term)
intoGenFOLH1B
Cancer3DFOLH1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609020   
Orphanet
DisGeNETFOLH1B
MedgenFOLH1B
Genetic Testing Registry FOLH1B
NextProtQ9HBA9 [Medical]
TSGene219595
GENETestsFOLH1B
Target ValidationFOLH1B
Huge Navigator FOLH1B [HugePedia]
snp3D : Map Gene to Disease219595
BioCentury BCIQFOLH1B
ClinGenFOLH1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219595
Chemical/Pharm GKB GenePA165543408
Clinical trialFOLH1B
Miscellaneous
canSAR (ICR)FOLH1B (select the gene name)
HarmonizomeFOLH1B
DataMed IndexFOLH1B
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOLH1B
EVEXFOLH1B
GoPubMedFOLH1B
iHOPFOLH1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 10 12:15:15 CEST 2020
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