| Nomenclature |
|---|
| HGNC (Hugo) | FOXA3 5023 |
| Cards |
|---|
| Entrez_Gene (NCBI) | FOXA3 3171 forkhead box A3 |
| Aliases | FKHH3; HNF3G; TCF3G |
| GeneCards (Weizmann) | FOXA3 |
| Ensembl hg19 (Hinxton) | ENSG00000170608 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000170608 [Gene_View] ENSG00000170608 [Sequence] chr19:45864260-45873797 [Contig_View] FOXA3 [Vega] |
| ICGC DataPortal | ENSG00000170608 |
| TCGA cBioPortal | FOXA3 |
| AceView (NCBI) | FOXA3 |
| Genatlas (Paris) | FOXA3 |
| WikiGenes | 3171 |
| SOURCE (Princeton) | FOXA3 |
| Genetics Home Reference (NIH) | FOXA3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | FOXA3 - chr19:45864260-45873797 + 19q13.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | FOXA3 - 19q13.32 [Description] (hg19-Feb_2009) |
| Ensembl | FOXA3 - 19q13.32 [CytoView hg19] FOXA3 - 19q13.32 [CytoView hg38] |
| Mapping of homologs : NCBI | FOXA3 [Mapview hg19] FOXA3 [Mapview hg38] |
| OMIM | 602295 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK223473 BC016024 BT006720 L12141 |
| RefSeq transcript (Entrez) | NM_004497 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | FOXA3 |
| Cluster EST : Unigene | Hs.36137 [ NCBI ] |
| CGAP (NCI) | Hs.36137 |
| Alternative Splicing Gallery | ENSG00000170608 |
| Gene Expression | FOXA3 [ NCBI-GEO ] FOXA3 [ EBI - ARRAY_EXPRESS ]
FOXA3 [ SEEK ] FOXA3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | FOXA3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3171 |
| GTEX Portal (Tissue expression) | FOXA3 |
| Human Protein Atlas | ENSG00000170608-FOXA3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P55318 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P55318 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P55318 |
| Splice isoforms : SwissVar | P55318 |
| PhosPhoSitePlus | P55318 |
| Domaine pattern : Prosite (Expaxy) | FORK_HEAD_1 (PS00657) FORK_HEAD_2 (PS00658) FORK_HEAD_3 (PS50039) |
| Domains : Interpro (EBI) | Fork-head_N Fork_head_dom TF_fork_head_CS_1 TF_fork_head_CS_2 WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Forkhead (PF00250) Forkhead_N (PF08430) |
| Domain families : Pfam (NCBI) | pfam00250 pfam08430 |
| Domain families : Smart (EMBL) | FH (SM00339) |
| Conserved Domain (NCBI) | FOXA3 |
| DMDM Disease mutations | 3171 |
| Blocks (Seattle) | FOXA3 |
| PDB (RSDB) | 1VTN |
| PDB Europe | 1VTN |
| PDB (PDBSum) | 1VTN |
| PDB (IMB) | 1VTN |
| Structural Biology KnowledgeBase | 1VTN |
| SCOP (Structural Classification of Proteins) | 1VTN |
| CATH (Classification of proteins structures) | 1VTN |
| Superfamily | P55318 |
| Human Protein Atlas [tissue] | ENSG00000170608-FOXA3 [tissue] |
| Peptide Atlas | P55318 |
| HPRD | 03802 |
| IPI | IPI00024388 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P55318 |
| IntAct (EBI) | P55318 |
| FunCoup | ENSG00000170608 |
| BioGRID | FOXA3 |
| STRING (EMBL) | FOXA3 |
| ZODIAC | FOXA3 |
| Ontologies - Pathways |
|---|
| QuickGO | P55318 |
| Ontology : AmiGO | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cellular glucose homeostasis DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleoplasm chromatin organization regulation of transcription by RNA polymerase II multicellular organism development spermatogenesis transcription factor binding cellular response to starvation anatomical structure morphogenesis actin cytoskeleton protein domain specific binding cell differentiation sequence-specific DNA binding transcription regulatory region DNA binding positive regulation of transcription by RNA polymerase II |
| Ontology : EGO-EBI | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cellular glucose homeostasis DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleoplasm chromatin organization regulation of transcription by RNA polymerase II multicellular organism development spermatogenesis transcription factor binding cellular response to starvation anatomical structure morphogenesis actin cytoskeleton protein domain specific binding cell differentiation sequence-specific DNA binding transcription regulatory region DNA binding positive regulation of transcription by RNA polymerase II |
| Pathways : KEGG | Maturity onset diabetes of the young |
| NDEx Network | FOXA3 |
| Atlas of Cancer Signalling Network | FOXA3 |
| Wikipedia pathways | FOXA3 |
| Orthology - Evolution |
|---|
| OrthoDB | 3171 |
| GeneTree (enSembl) | ENSG00000170608 |
| Phylogenetic Trees/Animal Genes : TreeFam | FOXA3 |
| HOGENOM | P55318 |
| Homologs : HomoloGene | FOXA3 |
| Homology/Alignments : Family Browser (UCSC) | FOXA3 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | FOXA3 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | FOXA3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | FOXA3 |
| dbVar | FOXA3 |
| ClinVar | FOXA3 |
| 1000_Genomes | FOXA3 |
| Exome Variant Server | FOXA3 |
| ExAC (Exome Aggregation Consortium) | ENSG00000170608 |
| GNOMAD Browser | ENSG00000170608 |
| Varsome Browser | FOXA3 |
| Genetic variants : HAPMAP | 3171 |
| Genomic Variants (DGV) | FOXA3 [DGVbeta] |
| DECIPHER | FOXA3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | FOXA3 |
| Mutations |
|---|
| ICGC Data Portal | FOXA3 |
| TCGA Data Portal | FOXA3 |
| Broad Tumor Portal | FOXA3 |
| OASIS Portal | FOXA3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | FOXA3 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | FOXA3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search FOXA3 |
| DgiDB (Drug Gene Interaction Database) | FOXA3 |
| DoCM (Curated mutations) | FOXA3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | FOXA3 (select a term) |
| intoGen | FOXA3 |
| Cancer3D | FOXA3(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 602295 |
| Orphanet | |
| DisGeNET | FOXA3 |
| Medgen | FOXA3 |
| Genetic Testing Registry | FOXA3
|
| NextProt | P55318 [Medical] |
| TSGene | 3171 |
| GENETests | FOXA3 |
| Target Validation | FOXA3 |
| Huge Navigator |
FOXA3 [HugePedia] |
| snp3D : Map Gene to Disease | 3171 |
| BioCentury BCIQ | FOXA3 |
| ClinGen | FOXA3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3171 |
| Chemical/Pharm GKB Gene | PA201092 |
| Clinical trial | FOXA3 |
| Miscellaneous |
|---|
| canSAR (ICR) | FOXA3 (select the gene name) |
| DataMed Index | FOXA3 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 28 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | FOXA3 |
| EVEX | FOXA3 |
| GoPubMed | FOXA3 |
| iHOP | FOXA3 |
