Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FOXA3 (forkhead box A3)

Identity

Alias_namesHNF3G
hepatocyte nuclear factor 3
Other aliasFKHH3
TCF3G
HGNC (Hugo) FOXA3
LocusID (NCBI) 3171
Atlas_Id 47123
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 45864260 and ends at 45873797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FOXA3   5023
Cards
Entrez_Gene (NCBI)FOXA3  3171  forkhead box A3
AliasesFKHH3; HNF3G; TCF3G
GeneCards (Weizmann)FOXA3
Ensembl hg19 (Hinxton)ENSG00000170608 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170608 [Gene_View]  ENSG00000170608 [Sequence]  chr19:45864260-45873797 [Contig_View]  FOXA3 [Vega]
ICGC DataPortalENSG00000170608
TCGA cBioPortalFOXA3
AceView (NCBI)FOXA3
Genatlas (Paris)FOXA3
WikiGenes3171
SOURCE (Princeton)FOXA3
Genetics Home Reference (NIH)FOXA3
Genomic and cartography
GoldenPath hg38 (UCSC)FOXA3  -     chr19:45864260-45873797 +  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXA3  -     19q13.32   [Description]    (hg19-Feb_2009)
EnsemblFOXA3 - 19q13.32 [CytoView hg19]  FOXA3 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIFOXA3 [Mapview hg19]  FOXA3 [Mapview hg38]
OMIM602295   
Gene and transcription
Genbank (Entrez)AK223473 BC016024 BT006720 L12141
RefSeq transcript (Entrez)NM_004497
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXA3
Cluster EST : UnigeneHs.36137 [ NCBI ]
CGAP (NCI)Hs.36137
Alternative Splicing GalleryENSG00000170608
Gene ExpressionFOXA3 [ NCBI-GEO ]   FOXA3 [ EBI - ARRAY_EXPRESS ]   FOXA3 [ SEEK ]   FOXA3 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3171
GTEX Portal (Tissue expression)FOXA3
Human Protein AtlasENSG00000170608-FOXA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55318   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55318  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55318
Splice isoforms : SwissVarP55318
PhosPhoSitePlusP55318
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork-head_N    Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)    Forkhead_N (PF08430)   
Domain families : Pfam (NCBI)pfam00250    pfam08430   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXA3
DMDM Disease mutations3171
Blocks (Seattle)FOXA3
PDB (SRS)1VTN   
PDB (PDBSum)1VTN   
PDB (IMB)1VTN   
PDB (RSDB)1VTN   
Structural Biology KnowledgeBase1VTN   
SCOP (Structural Classification of Proteins)1VTN   
CATH (Classification of proteins structures)1VTN   
SuperfamilyP55318
Human Protein Atlas [tissue]ENSG00000170608-FOXA3 [tissue]
Peptide AtlasP55318
HPRD03802
IPIIPI00024388   
Protein Interaction databases
DIP (DOE-UCLA)P55318
IntAct (EBI)P55318
FunCoupENSG00000170608
BioGRIDFOXA3
STRING (EMBL)FOXA3
ZODIACFOXA3
Ontologies - Pathways
QuickGOP55318
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  cellular glucose homeostasis  DNA binding transcription factor activity  DNA binding transcription factor activity  nucleus  nucleoplasm  transcription, DNA-templated  multicellular organism development  spermatogenesis  transcription factor binding  cellular response to starvation  anatomical structure morphogenesis  actin cytoskeleton  covalent chromatin modification  protein domain specific binding  cell differentiation  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  cellular glucose homeostasis  DNA binding transcription factor activity  DNA binding transcription factor activity  nucleus  nucleoplasm  transcription, DNA-templated  multicellular organism development  spermatogenesis  transcription factor binding  cellular response to starvation  anatomical structure morphogenesis  actin cytoskeleton  covalent chromatin modification  protein domain specific binding  cell differentiation  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  
Pathways : KEGGMaturity onset diabetes of the young   
NDEx NetworkFOXA3
Atlas of Cancer Signalling NetworkFOXA3
Wikipedia pathwaysFOXA3
Orthology - Evolution
OrthoDB3171
GeneTree (enSembl)ENSG00000170608
Phylogenetic Trees/Animal Genes : TreeFamFOXA3
HOVERGENP55318
HOGENOMP55318
Homologs : HomoloGeneFOXA3
Homology/Alignments : Family Browser (UCSC)FOXA3
Gene fusions - Rearrangements
Fusion : QuiverFOXA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXA3
dbVarFOXA3
ClinVarFOXA3
1000_GenomesFOXA3 
Exome Variant ServerFOXA3
ExAC (Exome Aggregation Consortium)ENSG00000170608
GNOMAD BrowserENSG00000170608
Genetic variants : HAPMAP3171
Genomic Variants (DGV)FOXA3 [DGVbeta]
DECIPHERFOXA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXA3 
Mutations
ICGC Data PortalFOXA3 
TCGA Data PortalFOXA3 
Broad Tumor PortalFOXA3
OASIS PortalFOXA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOXA3
DgiDB (Drug Gene Interaction Database)FOXA3
DoCM (Curated mutations)FOXA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXA3 (select a term)
intoGenFOXA3
Cancer3DFOXA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602295   
Orphanet
DisGeNETFOXA3
MedgenFOXA3
Genetic Testing Registry FOXA3
NextProtP55318 [Medical]
TSGene3171
GENETestsFOXA3
Target ValidationFOXA3
Huge Navigator FOXA3 [HugePedia]
snp3D : Map Gene to Disease3171
BioCentury BCIQFOXA3
ClinGenFOXA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3171
Chemical/Pharm GKB GenePA201092
Clinical trialFOXA3
Miscellaneous
canSAR (ICR)FOXA3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXA3
EVEXFOXA3
GoPubMedFOXA3
iHOPFOXA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:26:07 CEST 2018
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