| Nomenclature |
|---|
| HGNC (Hugo) | FOXA3 5023 |
| Cards |
|---|
| Entrez_Gene (NCBI) | FOXA3 3171 forkhead box A3 |
| Aliases | FKHH3; HNF3G; TCF3G |
| GeneCards (Weizmann) | FOXA3 |
| Ensembl hg19 (Hinxton) | ENSG00000170608 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000170608 [Gene_View] chr19:45864260-45873797 [Contig_View] FOXA3 [Vega] |
| ICGC DataPortal | ENSG00000170608 |
| TCGA cBioPortal | FOXA3 |
| AceView (NCBI) | FOXA3 |
| Genatlas (Paris) | FOXA3 |
| WikiGenes | 3171 |
| SOURCE (Princeton) | FOXA3 |
| Genetics Home Reference (NIH) | FOXA3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | FOXA3 - chr19:45864260-45873797 + 19q13.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | FOXA3 - 19q13.32 [Description] (hg19-Feb_2009) |
| Ensembl | FOXA3 - 19q13.32 [CytoView hg19] FOXA3 - 19q13.32 [CytoView hg38] |
| Mapping of homologs : NCBI | FOXA3 [Mapview hg19] FOXA3 [Mapview hg38] |
| OMIM | 602295 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK223473 BC016024 BT006720 L12141 |
| RefSeq transcript (Entrez) | NM_004497 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | FOXA3 |
| Cluster EST : Unigene | Hs.36137 [ NCBI ] |
| CGAP (NCI) | Hs.36137 |
| Alternative Splicing Gallery | ENSG00000170608 |
| Gene Expression | FOXA3 [ NCBI-GEO ] FOXA3 [ EBI - ARRAY_EXPRESS ]
FOXA3 [ SEEK ] FOXA3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | FOXA3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3171 |
| GTEX Portal (Tissue expression) | FOXA3 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P55318 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P55318 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P55318 |
| Splice isoforms : SwissVar | P55318 |
| PhosPhoSitePlus | P55318 |
| Domaine pattern : Prosite (Expaxy) | FORK_HEAD_1 (PS00657) FORK_HEAD_2 (PS00658) FORK_HEAD_3 (PS50039) |
| Domains : Interpro (EBI) | Fork-head_N Fork_head_dom TF_fork_head_CS_1 TF_fork_head_CS_2 WHTH_DNA-bd_dom |
| Domain families : Pfam (Sanger) | Forkhead (PF00250) Forkhead_N (PF08430) |
| Domain families : Pfam (NCBI) | pfam00250 pfam08430 |
| Domain families : Smart (EMBL) | FH (SM00339) |
| Conserved Domain (NCBI) | FOXA3 |
| DMDM Disease mutations | 3171 |
| Blocks (Seattle) | FOXA3 |
| PDB (SRS) | 1VTN |
| PDB (PDBSum) | 1VTN |
| PDB (IMB) | 1VTN |
| PDB (RSDB) | 1VTN |
| Structural Biology KnowledgeBase | 1VTN |
| SCOP (Structural Classification of Proteins) | 1VTN |
| CATH (Classification of proteins structures) | 1VTN |
| Superfamily | P55318 |
| Human Protein Atlas | ENSG00000170608 |
| Peptide Atlas | P55318 |
| HPRD | 03802 |
| IPI | IPI00024388 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P55318 |
| IntAct (EBI) | P55318 |
| FunCoup | ENSG00000170608 |
| BioGRID | FOXA3 |
| STRING (EMBL) | FOXA3 |
| ZODIAC | FOXA3 |
| Ontologies - Pathways |
|---|
| QuickGO | P55318 |
| Ontology : AmiGO | RNA polymerase II transcription factor activity, sequence-specific DNA binding cellular glucose homeostasis transcription factor activity, sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding nucleus nucleoplasm transcription, DNA-templated multicellular organism development spermatogenesis transcription factor binding cellular response to starvation actin cytoskeleton covalent chromatin modification protein domain specific binding cell differentiation sequence-specific DNA binding transcription regulatory region DNA binding positive regulation of transcription from RNA polymerase II promoter |
| Ontology : EGO-EBI | RNA polymerase II transcription factor activity, sequence-specific DNA binding cellular glucose homeostasis transcription factor activity, sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding nucleus nucleoplasm transcription, DNA-templated multicellular organism development spermatogenesis transcription factor binding cellular response to starvation actin cytoskeleton covalent chromatin modification protein domain specific binding cell differentiation sequence-specific DNA binding transcription regulatory region DNA binding positive regulation of transcription from RNA polymerase II promoter |
| Pathways : KEGG | Maturity onset diabetes of the young |
| NDEx Network | FOXA3 |
| Atlas of Cancer Signalling Network | FOXA3 |
| Wikipedia pathways | FOXA3 |
| Orthology - Evolution |
|---|
| OrthoDB | 3171 |
| GeneTree (enSembl) | ENSG00000170608 |
| Phylogenetic Trees/Animal Genes : TreeFam | FOXA3 |
| HOVERGEN | P55318 |
| HOGENOM | P55318 |
| Homologs : HomoloGene | FOXA3 |
| Homology/Alignments : Family Browser (UCSC) | FOXA3 |
| Gene fusions - Rearrangements |
|---|
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | FOXA3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | FOXA3 |
| dbVar | FOXA3 |
| ClinVar | FOXA3 |
| 1000_Genomes | FOXA3 |
| Exome Variant Server | FOXA3 |
| ExAC (Exome Aggregation Consortium) | FOXA3 (select the gene name) |
| Genetic variants : HAPMAP | 3171 |
| Genomic Variants (DGV) | FOXA3 [DGVbeta] |
| DECIPHER | FOXA3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | FOXA3 |
| Mutations |
|---|
| ICGC Data Portal | FOXA3 |
| TCGA Data Portal | FOXA3 |
| Broad Tumor Portal | FOXA3 |
| OASIS Portal | FOXA3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | FOXA3 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | FOXA3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search FOXA3 |
| DgiDB (Drug Gene Interaction Database) | FOXA3 |
| DoCM (Curated mutations) | FOXA3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | FOXA3 (select a term) |
| intoGen | FOXA3 |
| Cancer3D | FOXA3(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 602295 |
| Orphanet | |
| Medgen | FOXA3 |
| Genetic Testing Registry | FOXA3
|
| NextProt | P55318 [Medical] |
| TSGene | 3171 |
| GENETests | FOXA3 |
| Target Validation | FOXA3 |
| Huge Navigator |
FOXA3 [HugePedia] |
| snp3D : Map Gene to Disease | 3171 |
| BioCentury BCIQ | FOXA3 |
| ClinGen | FOXA3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3171 |
| Chemical/Pharm GKB Gene | PA201092 |
| Clinical trial | FOXA3 |
| Miscellaneous |
|---|
| canSAR (ICR) | FOXA3 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 25 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | FOXA3 |
| EVEX | FOXA3 |
| GoPubMed | FOXA3 |
| iHOP | FOXA3 |
