FOXC2 (forkhead box C2)

2007-04-01  

Identity

HGNC
LOCATION
16q24.1
LOCUSID
ALIAS
FKHL14,LD,MFH-1,MFH1

Other Information

Locus ID:

NCBI: 2303
MIM: 602402
HGNC: 3801
Ensembl: ENSG00000176692

Variants:

dbSNP: 2303
ClinVar: 2303
TCGA: ENSG00000176692
COSMIC: FOXC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176692ENST00000649859Q99958

Expression (GTEx)

0
10
20
30
40
50
60
70
80

References

Pubmed IDYearTitleCitations
175379112007Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers.217
169529802006Transcriptional genomics associates FOX transcription factors with human heart failure.89
121144782002Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.56
263896772015FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature.52
224107812013MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol.47
173721672007Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb.46
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45
283230302017Antisense lncRNA FOXC2-AS1 promotes doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2.43
253818152015FOXC2 promotes colorectal cancer metastasis by directly targeting MET.34
189748422008Gender differences in genetic risk profiles for cardiovascular disease.33

Citation

Dessen P

FOXC2 (forkhead box C2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46819/foxc2