Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FOXD1 (forkhead box D1)

Identity

Alias (NCBI)FKHL8
FREAC-4
FREAC4
HGNC (Hugo) FOXD1
HGNC Alias symbFREAC4
HGNC Previous nameFKHL8
LocusID (NCBI) 2297
Atlas_Id 40625
Location 5q13.2  [Link to chromosome band 5q13]
Location_base_pair Starts at 73446268 and ends at 73448777 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FOXD1   3802
Cards
Entrez_Gene (NCBI)FOXD1    forkhead box D1
AliasesFKHL8; FREAC-4; FREAC4
GeneCards (Weizmann)FOXD1
Ensembl hg19 (Hinxton)ENSG00000251493 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000251493 [Gene_View]  ENSG00000251493 [Sequence]  chr5:73446268-73448777 [Contig_View]  FOXD1 [Vega]
ICGC DataPortalENSG00000251493
TCGA cBioPortalFOXD1
AceView (NCBI)FOXD1
Genatlas (Paris)FOXD1
SOURCE (Princeton)FOXD1
Genetics Home Reference (NIH)FOXD1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXD1  -     chr5:73446268-73448777 -  5q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXD1  -     5q13.2   [Description]    (hg19-Feb_2009)
GoldenPathFOXD1 - 5q13.2 [CytoView hg19]  FOXD1 - 5q13.2 [CytoView hg38]
ImmunoBaseENSG00000251493
Genome Data Viewer NCBIFOXD1 [Mapview hg19]  
OMIM601091   
Gene and transcription
Genbank (Entrez)U13222 U59832
RefSeq transcript (Entrez)NM_004472
Consensus coding sequences : CCDS (NCBI)FOXD1
Gene ExpressionFOXD1 [ NCBI-GEO ]   FOXD1 [ EBI - ARRAY_EXPRESS ]   FOXD1 [ SEEK ]   FOXD1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXD1 [ Firebrowse - Broad ]
GenevisibleExpression of FOXD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2297
GTEX Portal (Tissue expression)FOXD1
Human Protein AtlasENSG00000251493-FOXD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16676   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16676  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16676
PhosPhoSitePlusQ16676
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXD1
SuperfamilyQ16676
AlphaFold pdb e-kbQ16676   
Human Protein Atlas [tissue]ENSG00000251493-FOXD1 [tissue]
HPRD03055
Protein Interaction databases
DIP (DOE-UCLA)Q16676
IntAct (EBI)Q16676
BioGRIDFOXD1
STRING (EMBL)FOXD1
ZODIACFOXD1
Ontologies - Pathways
QuickGOQ16676
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  axon guidance  DNA binding, bending  anatomical structure morphogenesis  positive regulation of gene expression  cell differentiation  positive regulation of BMP signaling pathway  luteinizing hormone secretion  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  dichotomous subdivision of terminal units involved in ureteric bud branching  nephrogenic mesenchyme development  metanephric nephron development  metanephric capsule development  metanephric capsule specification  positive regulation of kidney development  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  axon guidance  DNA binding, bending  anatomical structure morphogenesis  positive regulation of gene expression  cell differentiation  positive regulation of BMP signaling pathway  luteinizing hormone secretion  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  dichotomous subdivision of terminal units involved in ureteric bud branching  nephrogenic mesenchyme development  metanephric nephron development  metanephric capsule development  metanephric capsule specification  positive regulation of kidney development  
NDEx NetworkFOXD1
Atlas of Cancer Signalling NetworkFOXD1
Wikipedia pathwaysFOXD1
Orthology - Evolution
OrthoDB2297
GeneTree (enSembl)ENSG00000251493
Phylogenetic Trees/Animal Genes : TreeFamFOXD1
Homologs : HomoloGeneFOXD1
Homology/Alignments : Family Browser (UCSC)FOXD1
Gene fusions - Rearrangements
Fusion : QuiverFOXD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXD1
dbVarFOXD1
ClinVarFOXD1
MonarchFOXD1
1000_GenomesFOXD1 
Exome Variant ServerFOXD1
GNOMAD BrowserENSG00000251493
Varsome BrowserFOXD1
ACMGFOXD1 variants
VarityQ16676
Genomic Variants (DGV)FOXD1 [DGVbeta]
DECIPHERFOXD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXD1 
Mutations
ICGC Data PortalFOXD1 
TCGA Data PortalFOXD1 
Broad Tumor PortalFOXD1
OASIS PortalFOXD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFOXD1
Mutations and Diseases : HGMDFOXD1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFOXD1
DgiDB (Drug Gene Interaction Database)FOXD1
DoCM (Curated mutations)FOXD1
CIViC (Clinical Interpretations of Variants in Cancer)FOXD1
Cancer3DFOXD1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601091   
Orphanet
DisGeNETFOXD1
MedgenFOXD1
Genetic Testing Registry FOXD1
NextProtQ16676 [Medical]
GENETestsFOXD1
Target ValidationFOXD1
Huge Navigator FOXD1 [HugePedia]
ClinGenFOXD1
Clinical trials, drugs, therapy
MyCancerGenomeFOXD1
Protein Interactions : CTDFOXD1
Pharm GKB GenePA28219
PharosQ16676
Clinical trialFOXD1
Miscellaneous
canSAR (ICR)FOXD1
HarmonizomeFOXD1
ARCHS4FOXD1
DataMed IndexFOXD1
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFOXD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Jan 16 18:11:23 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.