Atlas of Genetics and Cytogenetics in Oncology and Haematology


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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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FOXE3 (forkhead box E3)

Identity

Other namesFKHL12
FREAC8
HGNC (Hugo) FOXE3
LocusID (NCBI) 2301
Location 1p33
Location_base_pair Starts at 47881744 and ends at 47883724 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FOXE3   3808
Cards
Entrez_Gene (NCBI)FOXE3  2301  forkhead box E3
GeneCards (Weizmann)FOXE3
Ensembl hg19 (Hinxton)ENSG00000186790 [Gene_View]  chr1:47881744-47883724 [Contig_View]  FOXE3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186790 [Gene_View]  chr1:47881744-47883724 [Contig_View]  FOXE3 [Vega]
ICGC DataPortalENSG00000186790
cBioPortalFOXE3
AceView (NCBI)FOXE3
Genatlas (Paris)FOXE3
WikiGenes2301
SOURCE (Princeton)FOXE3
Genomic and cartography
GoldenPath hg19 (UCSC)FOXE3  -     chr1:47881744-47883724 +  1p33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FOXE3  -     1p33   [Description]    (hg38-Dec_2013)
EnsemblFOXE3 - 1p33 [CytoView hg19]  FOXE3 - 1p33 [CytoView hg38]
Mapping of homologs : NCBIFOXE3 [Mapview hg19]  FOXE3 [Mapview hg38]
OMIM107250   601094   610256   
Gene and transcription
Genbank (Entrez)AF275722 BC172358
RefSeq transcript (Entrez)NM_012186
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_016192 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)FOXE3
Cluster EST : UnigeneHs.112968 [ NCBI ]
CGAP (NCI)Hs.112968
Alternative Splicing : Fast-db (Paris)GSHG0000493
Alternative Splicing GalleryENSG00000186790
Gene ExpressionFOXE3 [ NCBI-GEO ]     FOXE3 [ SEEK ]   FOXE3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13461 (Uniprot)
NextProtQ13461  [Medical]
With graphics : InterProQ13461
Splice isoforms : SwissVarQ13461 (Swissvar)
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)TF_fork_head    TF_fork_head_CS    WHTH_DNA-bd_dom   
Related proteins : CluSTrQ13461
Domain families : Pfam (Sanger)Fork_head (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
DMDM Disease mutations2301
Blocks (Seattle)Q13461
Human Protein AtlasENSG00000186790
Peptide AtlasQ13461
HPRD03058
IPIIPI00013354   
Protein Interaction databases
DIP (DOE-UCLA)Q13461
IntAct (EBI)Q13461
FunCoupENSG00000186790
BioGRIDFOXE3
IntegromeDBFOXE3
STRING (EMBL)FOXE3
Ontologies - Pathways
QuickGOQ13461
Ontology : AmiGOsequence-specific DNA binding RNA polymerase II transcription factor activity  sequence-specific DNA binding transcription factor activity  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  anatomical structure morphogenesis  cell differentiation  camera-type eye development  sequence-specific DNA binding  cell development  positive regulation of epithelial cell proliferation  
Ontology : EGO-EBIsequence-specific DNA binding RNA polymerase II transcription factor activity  sequence-specific DNA binding transcription factor activity  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  anatomical structure morphogenesis  cell differentiation  camera-type eye development  sequence-specific DNA binding  cell development  positive regulation of epithelial cell proliferation  
Protein Interaction DatabaseFOXE3
DoCM (Curated mutations)FOXE3
Wikipedia pathwaysFOXE3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerFOXE3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXE3
dbVarFOXE3
ClinVarFOXE3
1000_GenomesFOXE3 
Exome Variant ServerFOXE3
SNP (GeneSNP Utah)FOXE3
SNP : HGBaseFOXE3
Genetic variants : HAPMAPFOXE3
Genomic Variants (DGV)FOXE3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000186790 
Somatic Mutations in Cancer : COSMICFOXE3 
CONAN: Copy Number AnalysisFOXE3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:47881744-47883724
Mutations and Diseases : HGMDFOXE3
OMIM107250    601094    610256   
MedgenFOXE3
NextProtQ13461 [Medical]
GENETestsFOXE3
Disease Genetic AssociationFOXE3
Huge Navigator FOXE3 [HugePedia]  FOXE3 [HugeCancerGEM]
snp3D : Map Gene to Disease2301
DGIdb (Drug Gene Interaction db)FOXE3
General knowledge
Homologs : HomoloGeneFOXE3
Homology/Alignments : Family Browser (UCSC)FOXE3
Phylogenetic Trees/Animal Genes : TreeFamFOXE3
Chemical/Protein Interactions : CTD2301
Chemical/Pharm GKB GenePA28225
Clinical trialFOXE3
Cancer Resource (Charite)ENSG00000186790
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
CoreMineFOXE3
GoPubMedFOXE3
iHOPFOXE3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:26:09 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.