Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXE3 (forkhead box E3)

Identity

Alias (NCBI)AAT11
ASGD2
CTRCT34
FKHL12
FREAC8
HGNC (Hugo) FOXE3
HGNC Alias symbFREAC8
HGNC Previous nameFKHL12
LocusID (NCBI) 2301
Atlas_Id 46945
Location 1p33  [Link to chromosome band 1p33]
Location_base_pair Starts at 47416285 and ends at 47418052 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FOXE3   3808
Cards
Entrez_Gene (NCBI)FOXE3    forkhead box E3
AliasesAAT11; ASGD2; CTRCT34; FKHL12; 
FREAC8
GeneCards (Weizmann)FOXE3
Ensembl hg19 (Hinxton)ENSG00000186790 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186790 [Gene_View]  ENSG00000186790 [Sequence]  chr1:47416285-47418052 [Contig_View]  FOXE3 [Vega]
ICGC DataPortalENSG00000186790
TCGA cBioPortalFOXE3
AceView (NCBI)FOXE3
Genatlas (Paris)FOXE3
SOURCE (Princeton)FOXE3
Genetics Home Reference (NIH)FOXE3
Genomic and cartography
GoldenPath hg38 (UCSC)FOXE3  -     chr1:47416285-47418052 +  1p33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXE3  -     1p33   [Description]    (hg19-Feb_2009)
GoldenPathFOXE3 - 1p33 [CytoView hg19]  FOXE3 - 1p33 [CytoView hg38]
ImmunoBaseENSG00000186790
Genome Data Viewer NCBIFOXE3 [Mapview hg19]  
OMIM601094   610256   612968   617349   
Gene and transcription
Genbank (Entrez)AF275722 KM433708
RefSeq transcript (Entrez)NM_012186
Consensus coding sequences : CCDS (NCBI)FOXE3
Gene ExpressionFOXE3 [ NCBI-GEO ]   FOXE3 [ EBI - ARRAY_EXPRESS ]   FOXE3 [ SEEK ]   FOXE3 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXE3 [ Firebrowse - Broad ]
GenevisibleExpression of FOXE3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2301
GTEX Portal (Tissue expression)FOXE3
Human Protein AtlasENSG00000186790-FOXE3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13461   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13461  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13461
PhosPhoSitePlusQ13461
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXE3
SuperfamilyQ13461
AlphaFold pdb e-kbQ13461   
Human Protein Atlas [tissue]ENSG00000186790-FOXE3 [tissue]
HPRD03058
Protein Interaction databases
DIP (DOE-UCLA)Q13461
IntAct (EBI)Q13461
BioGRIDFOXE3
STRING (EMBL)FOXE3
ZODIACFOXE3
Ontologies - Pathways
QuickGOQ13461
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  eye development  lens development in camera-type eye  lens development in camera-type eye  trabecular meshwork development  DNA binding  DNA-binding transcription factor activity  DNA-binding transcription factor activity  nucleus  transcription regulator complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  anatomical structure morphogenesis  cell differentiation  mRNA transcription by RNA polymerase II  negative regulation of apoptotic process  sequence-specific DNA binding  cell development  regulation of cell cycle  iris morphogenesis  ciliary body morphogenesis  cornea development in camera-type eye  negative regulation of lens fiber cell differentiation  positive regulation of lens epithelial cell proliferation  positive regulation of lens epithelial cell proliferation  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  eye development  lens development in camera-type eye  lens development in camera-type eye  trabecular meshwork development  DNA binding  DNA-binding transcription factor activity  DNA-binding transcription factor activity  nucleus  transcription regulator complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  anatomical structure morphogenesis  cell differentiation  mRNA transcription by RNA polymerase II  negative regulation of apoptotic process  sequence-specific DNA binding  cell development  regulation of cell cycle  iris morphogenesis  ciliary body morphogenesis  cornea development in camera-type eye  negative regulation of lens fiber cell differentiation  positive regulation of lens epithelial cell proliferation  positive regulation of lens epithelial cell proliferation  
NDEx NetworkFOXE3
Atlas of Cancer Signalling NetworkFOXE3
Wikipedia pathwaysFOXE3
Orthology - Evolution
OrthoDB2301
GeneTree (enSembl)ENSG00000186790
Phylogenetic Trees/Animal Genes : TreeFamFOXE3
Homologs : HomoloGeneFOXE3
Homology/Alignments : Family Browser (UCSC)FOXE3
Gene fusions - Rearrangements
Fusion : QuiverFOXE3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXE3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXE3
dbVarFOXE3
ClinVarFOXE3
MonarchFOXE3
1000_GenomesFOXE3 
Exome Variant ServerFOXE3
GNOMAD BrowserENSG00000186790
Varsome BrowserFOXE3
ACMGFOXE3 variants
VarityQ13461
Genomic Variants (DGV)FOXE3 [DGVbeta]
DECIPHERFOXE3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXE3 
Mutations
ICGC Data PortalFOXE3 
TCGA Data PortalFOXE3 
Broad Tumor PortalFOXE3
OASIS PortalFOXE3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXE3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFOXE3
Mutations and Diseases : HGMDFOXE3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFOXE3
DgiDB (Drug Gene Interaction Database)FOXE3
DoCM (Curated mutations)FOXE3
CIViC (Clinical Interpretations of Variants in Cancer)FOXE3
Cancer3DFOXE3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601094    610256    612968    617349   
Orphanet11812    11574   
DisGeNETFOXE3
MedgenFOXE3
Genetic Testing Registry FOXE3
NextProtQ13461 [Medical]
GENETestsFOXE3
Target ValidationFOXE3
Huge Navigator FOXE3 [HugePedia]
ClinGenFOXE3
Clinical trials, drugs, therapy
MyCancerGenomeFOXE3
Protein Interactions : CTDFOXE3
Pharm GKB GenePA28225
PharosQ13461
Clinical trialFOXE3
Miscellaneous
canSAR (ICR)FOXE3
HarmonizomeFOXE3
DataMed IndexFOXE3
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFOXE3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:09:49 CEST 2021

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