Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXF2 (forkhead box F2)

Identity

Alias_namesFKHL6
Alias_symbol (synonym)FREAC2
Other aliasFREAC-2
HGNC (Hugo) FOXF2
LocusID (NCBI) 2295
Atlas_Id 47064
Location 6p25.3  [Link to chromosome band 6p25]
Location_base_pair Starts at 1389834 and ends at 1395597 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FOXF2   3810
LRG (Locus Reference Genomic)LRG_1190
Cards
Entrez_Gene (NCBI)FOXF2  2295  forkhead box F2
AliasesFKHL6; FREAC-2; FREAC2
GeneCards (Weizmann)FOXF2
Ensembl hg19 (Hinxton)ENSG00000137273 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137273 [Gene_View]  ENSG00000137273 [Sequence]  chr6:1389834-1395597 [Contig_View]  FOXF2 [Vega]
ICGC DataPortalENSG00000137273
TCGA cBioPortalFOXF2
AceView (NCBI)FOXF2
Genatlas (Paris)FOXF2
WikiGenes2295
SOURCE (Princeton)FOXF2
Genetics Home Reference (NIH)FOXF2
Genomic and cartography
GoldenPath hg38 (UCSC)FOXF2  -     chr6:1389834-1395597 +  6p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXF2  -     6p25.3   [Description]    (hg19-Feb_2009)
EnsemblFOXF2 - 6p25.3 [CytoView hg19]  FOXF2 - 6p25.3 [CytoView hg38]
Mapping of homologs : NCBIFOXF2 [Mapview hg19]  FOXF2 [Mapview hg38]
OMIM603250   
Gene and transcription
Genbank (Entrez)CA448136 U13220
RefSeq transcript (Entrez)NM_001452
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXF2
Cluster EST : UnigeneHs.484423 [ NCBI ]
CGAP (NCI)Hs.484423
Alternative Splicing GalleryENSG00000137273
Gene ExpressionFOXF2 [ NCBI-GEO ]   FOXF2 [ EBI - ARRAY_EXPRESS ]   FOXF2 [ SEEK ]   FOXF2 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2295
GTEX Portal (Tissue expression)FOXF2
Human Protein AtlasENSG00000137273-FOXF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12947   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12947  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12947
Splice isoforms : SwissVarQ12947
PhosPhoSitePlusQ12947
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXF2
DMDM Disease mutations2295
Blocks (Seattle)FOXF2
SuperfamilyQ12947
Human Protein Atlas [tissue]ENSG00000137273-FOXF2 [tissue]
Peptide AtlasQ12947
HPRD09131
IPIIPI00030319   
Protein Interaction databases
DIP (DOE-UCLA)Q12947
IntAct (EBI)Q12947
FunCoupENSG00000137273
BioGRIDFOXF2
STRING (EMBL)FOXF2
ZODIACFOXF2
Ontologies - Pathways
QuickGOQ12947
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  epithelial to mesenchymal transition  DNA binding  DNA-binding transcription factor activity  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  nucleus  transcription factor complex  transcription factor binding  extracellular matrix organization  establishment of planar polarity of embryonic epithelium  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  embryonic digestive tract development  embryonic camera-type eye morphogenesis  genitalia development  roof of mouth development  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  epithelial to mesenchymal transition  DNA binding  DNA-binding transcription factor activity  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  nucleus  transcription factor complex  transcription factor binding  extracellular matrix organization  establishment of planar polarity of embryonic epithelium  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  embryonic digestive tract development  embryonic camera-type eye morphogenesis  genitalia development  roof of mouth development  
NDEx NetworkFOXF2
Atlas of Cancer Signalling NetworkFOXF2
Wikipedia pathwaysFOXF2
Orthology - Evolution
OrthoDB2295
GeneTree (enSembl)ENSG00000137273
Phylogenetic Trees/Animal Genes : TreeFamFOXF2
HOVERGENQ12947
HOGENOMQ12947
Homologs : HomoloGeneFOXF2
Homology/Alignments : Family Browser (UCSC)FOXF2
Gene fusions - Rearrangements
Fusion : QuiverFOXF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXF2
dbVarFOXF2
ClinVarFOXF2
1000_GenomesFOXF2 
Exome Variant ServerFOXF2
ExAC (Exome Aggregation Consortium)ENSG00000137273
GNOMAD BrowserENSG00000137273
Varsome BrowserFOXF2
Genetic variants : HAPMAP2295
Genomic Variants (DGV)FOXF2 [DGVbeta]
DECIPHERFOXF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXF2 
Mutations
ICGC Data PortalFOXF2 
TCGA Data PortalFOXF2 
Broad Tumor PortalFOXF2
OASIS PortalFOXF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOXF2
DgiDB (Drug Gene Interaction Database)FOXF2
DoCM (Curated mutations)FOXF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXF2 (select a term)
intoGenFOXF2
Cancer3DFOXF2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603250   
Orphanet
DisGeNETFOXF2
MedgenFOXF2
Genetic Testing Registry FOXF2
NextProtQ12947 [Medical]
TSGene2295
GENETestsFOXF2
Target ValidationFOXF2
Huge Navigator FOXF2 [HugePedia]
snp3D : Map Gene to Disease2295
BioCentury BCIQFOXF2
ClinGenFOXF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2295
Chemical/Pharm GKB GenePA28227
Clinical trialFOXF2
Miscellaneous
canSAR (ICR)FOXF2 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXF2
EVEXFOXF2
GoPubMedFOXF2
iHOPFOXF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:07:06 CET 2018

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