Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXG1 (forkhead box G1)

Identity

Alias_namesFKHL2
FOXG1B
FKHL4
FKH2
FKHL1
FOXG1C
FKHL3
FOXG1A
forkhead box G1B
forkhead box G1C
forkhead box G1A
Alias_symbol (synonym)HFK2
QIN
BF1
HFK1
HFK3
HBF-3
Other aliasBF2
FHKL3
HBF-1
HBF-2
HBF-G2
HBF2
KHL2
HGNC (Hugo) FOXG1
LocusID (NCBI) 2290
Atlas_Id 40629
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 28767072 and ends at 28770277 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FOXG1 (14q12) / NPAS3 (14q13.1)FOXG1 (14q12) / RNF169 (11q13.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)FOXG1   3811
Cards
Entrez_Gene (NCBI)FOXG1  2290  forkhead box G1
AliasesBF1; BF2; FHKL3; FKH2; 
FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; HBF-1; HBF-2; HBF-3; HBF-G2; HBF2; HFK1; HFK2; HFK3; KHL2; QIN
GeneCards (Weizmann)FOXG1
Ensembl hg19 (Hinxton)ENSG00000176165 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176165 [Gene_View]  chr14:28767072-28770277 [Contig_View]  FOXG1 [Vega]
ICGC DataPortalENSG00000176165
TCGA cBioPortalFOXG1
AceView (NCBI)FOXG1
Genatlas (Paris)FOXG1
WikiGenes2290
SOURCE (Princeton)FOXG1
Genetics Home Reference (NIH)FOXG1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXG1  -     chr14:28767072-28770277 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXG1  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblFOXG1 - 14q12 [CytoView hg19]  FOXG1 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIFOXG1 [Mapview hg19]  FOXG1 [Mapview hg38]
OMIM164874   613454   
Gene and transcription
Genbank (Entrez)BC035020 BC040960 BC050072 DR001113 U44097
RefSeq transcript (Entrez)NM_005249
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXG1
Cluster EST : UnigeneHs.741222 [ NCBI ]
CGAP (NCI)Hs.741222
Alternative Splicing GalleryENSG00000176165
Gene ExpressionFOXG1 [ NCBI-GEO ]   FOXG1 [ EBI - ARRAY_EXPRESS ]   FOXG1 [ SEEK ]   FOXG1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2290
GTEX Portal (Tissue expression)FOXG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55316   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55316  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55316
Splice isoforms : SwissVarP55316
PhosPhoSitePlusP55316
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXG1
DMDM Disease mutations2290
Blocks (Seattle)FOXG1
SuperfamilyP55316
Human Protein AtlasENSG00000176165
Peptide AtlasP55316
HPRD01283
IPIIPI00024386   
Protein Interaction databases
DIP (DOE-UCLA)P55316
IntAct (EBI)P55316
FunCoupENSG00000176165
BioGRIDFOXG1
STRING (EMBL)FOXG1
ZODIACFOXG1
Ontologies - Pathways
QuickGOP55316
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of mitotic cell cycle  brain development  aging  dorsal/ventral pattern formation  axon midline choice point recognition  pyramidal neuron migration  inner ear morphogenesis  sequence-specific DNA binding  negative regulation of neuron differentiation  positive regulation of neuron differentiation  positive regulation of cell cycle  negative regulation of transcription, DNA-templated  neuron fate determination  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of mitotic cell cycle  brain development  aging  dorsal/ventral pattern formation  axon midline choice point recognition  pyramidal neuron migration  inner ear morphogenesis  sequence-specific DNA binding  negative regulation of neuron differentiation  positive regulation of neuron differentiation  positive regulation of cell cycle  negative regulation of transcription, DNA-templated  neuron fate determination  
Pathways : KEGGFoxO signaling pathway   
NDEx NetworkFOXG1
Atlas of Cancer Signalling NetworkFOXG1
Wikipedia pathwaysFOXG1
Orthology - Evolution
OrthoDB2290
GeneTree (enSembl)ENSG00000176165
Phylogenetic Trees/Animal Genes : TreeFamFOXG1
HOVERGENP55316
HOGENOMP55316
Homologs : HomoloGeneFOXG1
Homology/Alignments : Family Browser (UCSC)FOXG1
Gene fusions - Rearrangements
Fusion : MitelmanFOXG1/NPAS3 [14q12/14q13.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXG1
dbVarFOXG1
ClinVarFOXG1
1000_GenomesFOXG1 
Exome Variant ServerFOXG1
ExAC (Exome Aggregation Consortium)FOXG1 (select the gene name)
Genetic variants : HAPMAP2290
Genomic Variants (DGV)FOXG1 [DGVbeta]
DECIPHERFOXG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXG1 
Mutations
ICGC Data PortalFOXG1 
TCGA Data PortalFOXG1 
Broad Tumor PortalFOXG1
OASIS PortalFOXG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch FOXG1
DgiDB (Drug Gene Interaction Database)FOXG1
DoCM (Curated mutations)FOXG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXG1 (select a term)
intoGenFOXG1
Cancer3DFOXG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164874    613454   
Orphanet19853    19861    3164   
MedgenFOXG1
Genetic Testing Registry FOXG1
NextProtP55316 [Medical]
TSGene2290
GENETestsFOXG1
Target ValidationFOXG1
Huge Navigator FOXG1 [HugePedia]
snp3D : Map Gene to Disease2290
BioCentury BCIQFOXG1
ClinGenFOXG1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2290
Chemical/Pharm GKB GenePA162388806
Clinical trialFOXG1
Miscellaneous
canSAR (ICR)FOXG1 (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXG1
EVEXFOXG1
GoPubMedFOXG1
iHOPFOXG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:08:51 CEST 2017

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