Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FOXG1 (forkhead box G1)

Identity

Alias (NCBI)BF1
BF2
FHKL3
FKH2
FKHL1
FKHL2
FKHL3
FKHL4
FOXG1A
FOXG1B
FOXG1C
HBF-1
HBF-2
HBF-3
HBF-G2
HBF2
HFK1
HFK2
HFK3
KHL2
QIN
HGNC (Hugo) FOXG1
HGNC Alias symbHFK2
QIN
BF1
HFK1
HFK3
HBF-3
HGNC Alias namebrain factor 1
HGNC Previous nameFKHL2
 FOXG1B
 FKHL4
 FKH2
 FKHL1
 FOXG1C
 FKHL3
 FOXG1A
HGNC Previous nameforkhead box G1B
 forkhead box G1C
 forkhead box G1A
LocusID (NCBI) 2290
Atlas_Id 40629
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 28766787 and ends at 28770277 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FOXG1 (14q12) / NPAS3 (14q13.1)FOXG1 (14q12) / RNF169 (11q13.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FOXG1   3811
Cards
Entrez_Gene (NCBI)FOXG1    forkhead box G1
AliasesBF1; BF2; FHKL3; FKH2; 
FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; HBF-1; HBF-2; HBF-3; HBF-G2; HBF2; HFK1; HFK2; HFK3; KHL2; QIN
GeneCards (Weizmann)FOXG1
Ensembl hg19 (Hinxton)ENSG00000176165 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176165 [Gene_View]  ENSG00000176165 [Sequence]  chr14:28766787-28770277 [Contig_View]  FOXG1 [Vega]
ICGC DataPortalENSG00000176165
TCGA cBioPortalFOXG1
AceView (NCBI)FOXG1
Genatlas (Paris)FOXG1
SOURCE (Princeton)FOXG1
Genetics Home Reference (NIH)FOXG1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXG1  -     chr14:28766787-28770277 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXG1  -     14q12   [Description]    (hg19-Feb_2009)
GoldenPathFOXG1 - 14q12 [CytoView hg19]  FOXG1 - 14q12 [CytoView hg38]
ImmunoBaseENSG00000176165
Genome Data Viewer NCBIFOXG1 [Mapview hg19]  
OMIM164874   613454   
Gene and transcription
Genbank (Entrez)BC035020 BC040960 BC050072 DR001113 U44097
RefSeq transcript (Entrez)NM_005249
Consensus coding sequences : CCDS (NCBI)FOXG1
Gene ExpressionFOXG1 [ NCBI-GEO ]   FOXG1 [ EBI - ARRAY_EXPRESS ]   FOXG1 [ SEEK ]   FOXG1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXG1 [ Firebrowse - Broad ]
GenevisibleExpression of FOXG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2290
GTEX Portal (Tissue expression)FOXG1
Human Protein AtlasENSG00000176165-FOXG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55316   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55316  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55316
PhosPhoSitePlusP55316
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXG1
PDB (RSDB)7CBY   
PDB Europe7CBY   
PDB (PDBSum)7CBY   
PDB (IMB)7CBY   
Structural Biology KnowledgeBase7CBY   
SCOP (Structural Classification of Proteins)7CBY   
CATH (Classification of proteins structures)7CBY   
SuperfamilyP55316
AlphaFold pdb e-kbP55316   
Human Protein Atlas [tissue]ENSG00000176165-FOXG1 [tissue]
HPRD01283
Protein Interaction databases
DIP (DOE-UCLA)P55316
IntAct (EBI)P55316
BioGRIDFOXG1
STRING (EMBL)FOXG1
ZODIACFOXG1
Ontologies - Pathways
QuickGOP55316
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  regulation of mitotic cell cycle  brain development  aging  dorsal/ventral pattern formation  axon midline choice point recognition  pyramidal neuron migration  inner ear morphogenesis  negative regulation of neuron differentiation  positive regulation of neuron differentiation  positive regulation of cell cycle  negative regulation of transcription, DNA-templated  neuron fate determination  sequence-specific double-stranded DNA binding  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  regulation of mitotic cell cycle  brain development  aging  dorsal/ventral pattern formation  axon midline choice point recognition  pyramidal neuron migration  inner ear morphogenesis  negative regulation of neuron differentiation  positive regulation of neuron differentiation  positive regulation of cell cycle  negative regulation of transcription, DNA-templated  neuron fate determination  sequence-specific double-stranded DNA binding  sequence-specific double-stranded DNA binding  
Pathways : KEGGFoxO signaling pathway   
NDEx NetworkFOXG1
Atlas of Cancer Signalling NetworkFOXG1
Wikipedia pathwaysFOXG1
Orthology - Evolution
OrthoDB2290
GeneTree (enSembl)ENSG00000176165
Phylogenetic Trees/Animal Genes : TreeFamFOXG1
Homologs : HomoloGeneFOXG1
Homology/Alignments : Family Browser (UCSC)FOXG1
Gene fusions - Rearrangements
Fusion : MitelmanFOXG1/NPAS3 [14q12/14q13.1]  
Fusion : QuiverFOXG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXG1
dbVarFOXG1
ClinVarFOXG1
MonarchFOXG1
1000_GenomesFOXG1 
Exome Variant ServerFOXG1
GNOMAD BrowserENSG00000176165
Varsome BrowserFOXG1
ACMGFOXG1 variants
VarityP55316
Genomic Variants (DGV)FOXG1 [DGVbeta]
DECIPHERFOXG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXG1 
Mutations
ICGC Data PortalFOXG1 
TCGA Data PortalFOXG1 
Broad Tumor PortalFOXG1
OASIS PortalFOXG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFOXG1
Mutations and Diseases : HGMDFOXG1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFOXG1
DgiDB (Drug Gene Interaction Database)FOXG1
DoCM (Curated mutations)FOXG1
CIViC (Clinical Interpretations of Variants in Cancer)FOXG1
Cancer3DFOXG1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164874    613454   
Orphanet19853    19861    3164   
DisGeNETFOXG1
MedgenFOXG1
Genetic Testing Registry FOXG1
NextProtP55316 [Medical]
GENETestsFOXG1
Target ValidationFOXG1
Huge Navigator FOXG1 [HugePedia]
ClinGenFOXG1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeFOXG1
Protein Interactions : CTDFOXG1
Pharm GKB GenePA162388806
PharosP55316
Clinical trialFOXG1
Miscellaneous
canSAR (ICR)FOXG1
HarmonizomeFOXG1
DataMed IndexFOXG1
Probes
Litterature
PubMed101 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFOXG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:09:50 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.