FOXG1 (forkhead box G1)

2003-02-01  

Identity

HGNC
LOCATION
14q12
LOCUSID
ALIAS
BF1,BF2,FHKL3,FKH2,FKHL1,FKHL2,FKHL3,FKHL4,FOXG1A,FOXG1B,FOXG1C,HBF-1,HBF-2,HBF-3,HBF-G2,HBF2,HFK1,HFK2,HFK3,KHL2,QIN
FUSION GENES

Other Information

Locus ID:

NCBI: 2290
MIM: 164874
HGNC: 3811
Ensembl: ENSG00000176165

Variants:

dbSNP: 2290
ClinVar: 2290
TCGA: ENSG00000176165
COSMIC: FOXG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176165ENST00000313071P55316

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
FoxO signaling pathwayKEGGhsa04068

References

Pubmed IDYearTitleCitations
261861912015FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders.237
213680522011MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors.137
185711422008FOXG1 is responsible for the congenital variant of Rett syndrome.116
214412622011The core FOXG1 syndrome phenotype consists of postnatal microcephaly, severe mental retardation, absent language, dyskinesia, and corpus callosum hypogenesis.65
264553922015EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.48
207369782011Duplications of FOXG1 in 14q12 are associated with developmental epilepsy, mental retardation, and severe speech impairment.45
195780372010Novel FOXG1 mutations associated with the congenital variant of Rett syndrome.40
265239712015An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development.38
126576352003Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9.33
198063732010Revisiting the phenotype associated with FOXG1 mutations: two novel cases of congenital Rett variant.30

Citation

Dessen P

FOXG1 (forkhead box G1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40629/foxg1