Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FOXI1 (forkhead box I1)

Identity

Alias_namesFKHL10
Alias_symbol (synonym)FREAC6
Other aliasFKH10
FREAC-6
HFH-3
HFH3
HGNC (Hugo) FOXI1
LocusID (NCBI) 2299
Atlas_Id 46644
Location 5q35.1  [Link to chromosome band 5q35]
Location_base_pair Starts at 170105913 and ends at 170109725 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FOXI1   3815
Cards
Entrez_Gene (NCBI)FOXI1  2299  forkhead box I1
AliasesFKH10; FKHL10; FREAC-6; FREAC6; 
HFH-3; HFH3
GeneCards (Weizmann)FOXI1
Ensembl hg19 (Hinxton)ENSG00000168269 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168269 [Gene_View]ENSG00000168269 [Sequence]  chr5:170105913-170109725 [Contig_View]  FOXI1 [Vega]
ICGC DataPortalENSG00000168269
TCGA cBioPortalFOXI1
AceView (NCBI)FOXI1
Genatlas (Paris)FOXI1
WikiGenes2299
SOURCE (Princeton)FOXI1
Genetics Home Reference (NIH)FOXI1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXI1  -     chr5:170105913-170109725 +  5q35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXI1  -     5q35.1   [Description]    (hg19-Feb_2009)
EnsemblFOXI1 - 5q35.1 [CytoView hg19]  FOXI1 - 5q35.1 [CytoView hg38]
Mapping of homologs : NCBIFOXI1 [Mapview hg19]  FOXI1 [Mapview hg38]
OMIM274600   600791   601093   
Gene and transcription
Genbank (Entrez)AK292176 AY707089 BC029778 L13203
RefSeq transcript (Entrez)NM_012188 NM_144769
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXI1
Cluster EST : UnigeneHs.87236 [ NCBI ]
CGAP (NCI)Hs.87236
Alternative Splicing GalleryENSG00000168269
Gene ExpressionFOXI1 [ NCBI-GEO ]   FOXI1 [ EBI - ARRAY_EXPRESS ]   FOXI1 [ SEEK ]   FOXI1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2299
GTEX Portal (Tissue expression)FOXI1
Human Protein AtlasENSG00000168269-FOXI1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12951   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12951  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12951
Splice isoforms : SwissVarQ12951
PhosPhoSitePlusQ12951
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    Foxi1    TF_fork_head_CS_1    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXI1
DMDM Disease mutations2299
Blocks (Seattle)FOXI1
SuperfamilyQ12951
Human Protein Atlas [tissue]ENSG00000168269-FOXI1 [tissue]
Peptide AtlasQ12951
HPRD03057
IPIIPI00220405   IPI00158273   
Protein Interaction databases
DIP (DOE-UCLA)Q12951
IntAct (EBI)Q12951
FunCoupENSG00000168269
BioGRIDFOXI1
STRING (EMBL)FOXI1
ZODIACFOXI1
Ontologies - Pathways
QuickGOQ12951
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding  DNA binding transcription factor activity  nucleus  nucleus  nucleolus  transcription by RNA polymerase II  DNA binding, bending  anatomical structure morphogenesis  embryo development ending in birth or egg hatching  cell differentiation  inner ear morphogenesis  intracellular membrane-bounded organelle  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding  DNA binding transcription factor activity  nucleus  nucleus  nucleolus  transcription by RNA polymerase II  DNA binding, bending  anatomical structure morphogenesis  embryo development ending in birth or egg hatching  cell differentiation  inner ear morphogenesis  intracellular membrane-bounded organelle  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  
NDEx NetworkFOXI1
Atlas of Cancer Signalling NetworkFOXI1
Wikipedia pathwaysFOXI1
Orthology - Evolution
OrthoDB2299
GeneTree (enSembl)ENSG00000168269
Phylogenetic Trees/Animal Genes : TreeFamFOXI1
HOVERGENQ12951
HOGENOMQ12951
Homologs : HomoloGeneFOXI1
Homology/Alignments : Family Browser (UCSC)FOXI1
Gene fusions - Rearrangements
Fusion : QuiverFOXI1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXI1
dbVarFOXI1
ClinVarFOXI1
1000_GenomesFOXI1 
Exome Variant ServerFOXI1
ExAC (Exome Aggregation Consortium)ENSG00000168269
GNOMAD BrowserENSG00000168269
Genetic variants : HAPMAP2299
Genomic Variants (DGV)FOXI1 [DGVbeta]
DECIPHERFOXI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXI1 
Mutations
ICGC Data PortalFOXI1 
TCGA Data PortalFOXI1 
Broad Tumor PortalFOXI1
OASIS PortalFOXI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch FOXI1
DgiDB (Drug Gene Interaction Database)FOXI1
DoCM (Curated mutations)FOXI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXI1 (select a term)
intoGenFOXI1
Cancer3DFOXI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM274600    600791    601093   
Orphanet558   
DisGeNETFOXI1
MedgenFOXI1
Genetic Testing Registry FOXI1
NextProtQ12951 [Medical]
TSGene2299
GENETestsFOXI1
Target ValidationFOXI1
Huge Navigator FOXI1 [HugePedia]
snp3D : Map Gene to Disease2299
BioCentury BCIQFOXI1
ClinGenFOXI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2299
Chemical/Pharm GKB GenePA28232
Clinical trialFOXI1
Miscellaneous
canSAR (ICR)FOXI1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXI1
EVEXFOXI1
GoPubMedFOXI1
iHOPFOXI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jun 21 16:51:02 CEST 2018
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