Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXK1 (forkhead box K1)

Identity

Alias_symbol (synonym)IMAGE:5164497
Other aliasFOXK1L
HGNC (Hugo) FOXK1
LocusID (NCBI) 221937
Atlas_Id 55896
Location 7p22.1  [Link to chromosome band 7p22]
Location_base_pair Starts at 4682299 and ends at 4771443 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FOXK1 (7p22.1) / RCL1 (9p24.1)FOXK1 (7p22.1) / SDHB (1p36.13)UBR4 (1p36.13) / FOXK1 (7p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FOXK1   23480
Cards
Entrez_Gene (NCBI)FOXK1  221937  forkhead box K1
AliasesFOXK1L
GeneCards (Weizmann)FOXK1
Ensembl hg19 (Hinxton)ENSG00000164916 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164916 [Gene_View]  ENSG00000164916 [Sequence]  chr7:4682299-4771443 [Contig_View]  FOXK1 [Vega]
ICGC DataPortalENSG00000164916
TCGA cBioPortalFOXK1
AceView (NCBI)FOXK1
Genatlas (Paris)FOXK1
WikiGenes221937
SOURCE (Princeton)FOXK1
Genetics Home Reference (NIH)FOXK1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXK1  -     chr7:4682299-4771443 +  7p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXK1  -     7p22.1   [Description]    (hg19-Feb_2009)
EnsemblFOXK1 - 7p22.1 [CytoView hg19]  FOXK1 - 7p22.1 [CytoView hg38]
Mapping of homologs : NCBIFOXK1 [Mapview hg19]  FOXK1 [Mapview hg38]
OMIM616302   
Gene and transcription
Genbank (Entrez)AK027883 AK122663 AK302243 AW205747 BC038434
RefSeq transcript (Entrez)NM_001037165
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXK1
Cluster EST : UnigeneHs.487393 [ NCBI ]
CGAP (NCI)Hs.487393
Alternative Splicing GalleryENSG00000164916
Gene ExpressionFOXK1 [ NCBI-GEO ]   FOXK1 [ EBI - ARRAY_EXPRESS ]   FOXK1 [ SEEK ]   FOXK1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221937
GTEX Portal (Tissue expression)FOXK1
Human Protein AtlasENSG00000164916-FOXK1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP85037   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP85037  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP85037
Splice isoforms : SwissVarP85037
PhosPhoSitePlusP85037
Domaine pattern : Prosite (Expaxy)FHA_DOMAIN (PS50006)    FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)FHA_dom    Fork_head_dom    SMAD_FHA_dom_sf    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)FHA (PF00498)    Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00498    pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  FHA (SM00240)  
Conserved Domain (NCBI)FOXK1
DMDM Disease mutations221937
Blocks (Seattle)FOXK1
SuperfamilyP85037
Human Protein Atlas [tissue]ENSG00000164916-FOXK1 [tissue]
Peptide AtlasP85037
HPRD18750
IPIIPI00556645   IPI00807514   IPI01013576   IPI01009296   
Protein Interaction databases
DIP (DOE-UCLA)P85037
IntAct (EBI)P85037
FunCoupENSG00000164916
BioGRIDFOXK1
STRING (EMBL)FOXK1
ZODIACFOXK1
Ontologies - Pathways
QuickGOP85037
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  transcription regulatory region sequence-specific DNA binding  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific  protein binding  nucleus  nucleoplasm  cytoplasm  muscle organ development  protein deubiquitination  cell differentiation  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  transcription regulatory region sequence-specific DNA binding  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific  protein binding  nucleus  nucleoplasm  cytoplasm  muscle organ development  protein deubiquitination  cell differentiation  positive regulation of transcription by RNA polymerase II  
NDEx NetworkFOXK1
Atlas of Cancer Signalling NetworkFOXK1
Wikipedia pathwaysFOXK1
Orthology - Evolution
OrthoDB221937
GeneTree (enSembl)ENSG00000164916
Phylogenetic Trees/Animal Genes : TreeFamFOXK1
HOVERGENP85037
HOGENOMP85037
Homologs : HomoloGeneFOXK1
Homology/Alignments : Family Browser (UCSC)FOXK1
Gene fusions - Rearrangements
Fusion : QuiverFOXK1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXK1
dbVarFOXK1
ClinVarFOXK1
1000_GenomesFOXK1 
Exome Variant ServerFOXK1
ExAC (Exome Aggregation Consortium)ENSG00000164916
GNOMAD BrowserENSG00000164916
Varsome BrowserFOXK1
Genetic variants : HAPMAP221937
Genomic Variants (DGV)FOXK1 [DGVbeta]
DECIPHERFOXK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXK1 
Mutations
ICGC Data PortalFOXK1 
TCGA Data PortalFOXK1 
Broad Tumor PortalFOXK1
OASIS PortalFOXK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOXK1
DgiDB (Drug Gene Interaction Database)FOXK1
DoCM (Curated mutations)FOXK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXK1 (select a term)
intoGenFOXK1
Cancer3DFOXK1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616302   
Orphanet
DisGeNETFOXK1
MedgenFOXK1
Genetic Testing Registry FOXK1
NextProtP85037 [Medical]
TSGene221937
GENETestsFOXK1
Target ValidationFOXK1
Huge Navigator FOXK1 [HugePedia]
snp3D : Map Gene to Disease221937
BioCentury BCIQFOXK1
ClinGenFOXK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221937
Chemical/Pharm GKB GenePA134978307
Clinical trialFOXK1
Miscellaneous
canSAR (ICR)FOXK1 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXK1
EVEXFOXK1
GoPubMedFOXK1
iHOPFOXK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:07:08 CET 2018

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