Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXL1 (forkhead box L1)

Identity

Alias (NCBI)FKH6
FKHL11
FREAC7
HGNC (Hugo) FOXL1
HGNC Alias symbFREAC7
FKH6
HGNC Previous nameFKHL11
LocusID (NCBI) 2300
Atlas_Id 47339
Location 16q24.1  [Link to chromosome band 16q24]
Location_base_pair Starts at 86578549 and ends at 86583476 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FOXL1   3817
LRG (Locus Reference Genomic)LRG_709
Cards
Entrez_Gene (NCBI)FOXL1    forkhead box L1
AliasesFKH6; FKHL11; FREAC7
GeneCards (Weizmann)FOXL1
Ensembl hg19 (Hinxton)ENSG00000176678 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176678 [Gene_View]  ENSG00000176678 [Sequence]  chr16:86578549-86583476 [Contig_View]  FOXL1 [Vega]
ICGC DataPortalENSG00000176678
TCGA cBioPortalFOXL1
AceView (NCBI)FOXL1
Genatlas (Paris)FOXL1
SOURCE (Princeton)FOXL1
Genetics Home Reference (NIH)FOXL1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXL1  -     chr16:86578549-86583476 +  16q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXL1  -     16q24.1   [Description]    (hg19-Feb_2009)
GoldenPathFOXL1 - 16q24.1 [CytoView hg19]  FOXL1 - 16q24.1 [CytoView hg38]
ImmunoBaseENSG00000176678
Genome Data Viewer NCBIFOXL1 [Mapview hg19]  
OMIM603252   
Gene and transcription
Genbank (Entrez)BC100027 BC117226 BM675371
RefSeq transcript (Entrez)NM_005250
Consensus coding sequences : CCDS (NCBI)FOXL1
Gene ExpressionFOXL1 [ NCBI-GEO ]   FOXL1 [ EBI - ARRAY_EXPRESS ]   FOXL1 [ SEEK ]   FOXL1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXL1 [ Firebrowse - Broad ]
GenevisibleExpression of FOXL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2300
GTEX Portal (Tissue expression)FOXL1
Human Protein AtlasENSG00000176678-FOXL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12952   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12952  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12952
PhosPhoSitePlusQ12952
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXL1
SuperfamilyQ12952
AlphaFold pdb e-kbQ12952   
Human Protein Atlas [tissue]ENSG00000176678-FOXL1 [tissue]
HPRD07219
Protein Interaction databases
DIP (DOE-UCLA)Q12952
IntAct (EBI)Q12952
BioGRIDFOXL1
STRING (EMBL)FOXL1
ZODIACFOXL1
Ontologies - Pathways
QuickGOQ12952
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  visceral mesoderm-endoderm interaction involved in midgut development  heart development  DNA binding, bending  anatomical structure morphogenesis  regulation of Wnt signaling pathway  cell differentiation  proteoglycan biosynthetic process  sequence-specific DNA binding  Peyer's patch morphogenesis  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  visceral mesoderm-endoderm interaction involved in midgut development  heart development  DNA binding, bending  anatomical structure morphogenesis  regulation of Wnt signaling pathway  cell differentiation  proteoglycan biosynthetic process  sequence-specific DNA binding  Peyer's patch morphogenesis  
NDEx NetworkFOXL1
Atlas of Cancer Signalling NetworkFOXL1
Wikipedia pathwaysFOXL1
Orthology - Evolution
OrthoDB2300
GeneTree (enSembl)ENSG00000176678
Phylogenetic Trees/Animal Genes : TreeFamFOXL1
Homologs : HomoloGeneFOXL1
Homology/Alignments : Family Browser (UCSC)FOXL1
Gene fusions - Rearrangements
Fusion : QuiverFOXL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXL1
dbVarFOXL1
ClinVarFOXL1
MonarchFOXL1
1000_GenomesFOXL1 
Exome Variant ServerFOXL1
GNOMAD BrowserENSG00000176678
Varsome BrowserFOXL1
ACMGFOXL1 variants
VarityQ12952
Genomic Variants (DGV)FOXL1 [DGVbeta]
DECIPHERFOXL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXL1 
Mutations
ICGC Data PortalFOXL1 
TCGA Data PortalFOXL1 
Broad Tumor PortalFOXL1
OASIS PortalFOXL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFOXL1
Mutations and Diseases : HGMDFOXL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFOXL1
DgiDB (Drug Gene Interaction Database)FOXL1
DoCM (Curated mutations)FOXL1
CIViC (Clinical Interpretations of Variants in Cancer)FOXL1
Cancer3DFOXL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603252   
Orphanet
DisGeNETFOXL1
MedgenFOXL1
Genetic Testing Registry FOXL1
NextProtQ12952 [Medical]
GENETestsFOXL1
Target ValidationFOXL1
Huge Navigator FOXL1 [HugePedia]
ClinGenFOXL1
Clinical trials, drugs, therapy
MyCancerGenomeFOXL1
Protein Interactions : CTDFOXL1
Pharm GKB GenePA28234
PharosQ12952
Clinical trialFOXL1
Miscellaneous
canSAR (ICR)FOXL1
HarmonizomeFOXL1
ARCHS4FOXL1
DataMed IndexFOXL1
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFOXL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:34:04 CET 2022

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