Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXN1 (forkhead box N1)

Identity

Alias_namesWHN
RONU
winged-helix nude
Rowett nude
Alias_symbol (synonym)FKHL20
Other alias
HGNC (Hugo) FOXN1
LocusID (NCBI) 8456
Atlas_Id 46997
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 28523941 and ends at 28538157 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FOXN1   12765
LRG (Locus Reference Genomic)LRG_61
Cards
Entrez_Gene (NCBI)FOXN1  8456  forkhead box N1
AliasesFKHL20; RONU; WHN
GeneCards (Weizmann)FOXN1
Ensembl hg19 (Hinxton)ENSG00000109101 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109101 [Gene_View]  chr17:28523941-28538157 [Contig_View]  FOXN1 [Vega]
ICGC DataPortalENSG00000109101
TCGA cBioPortalFOXN1
AceView (NCBI)FOXN1
Genatlas (Paris)FOXN1
WikiGenes8456
SOURCE (Princeton)FOXN1
Genetics Home Reference (NIH)FOXN1
Genomic and cartography
GoldenPath hg38 (UCSC)FOXN1  -     chr17:28523941-28538157 +  17q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXN1  -     17q11.2   [Description]    (hg19-Feb_2009)
EnsemblFOXN1 - 17q11.2 [CytoView hg19]  FOXN1 - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBIFOXN1 [Mapview hg19]  FOXN1 [Mapview hg38]
OMIM600838   601705   
Gene and transcription
Genbank (Entrez)AF086453 AK313878 BC140423 BC146539 Y11739
RefSeq transcript (Entrez)NM_003593
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXN1
Cluster EST : UnigeneHs.663679 [ NCBI ]
CGAP (NCI)Hs.663679
Alternative Splicing GalleryENSG00000109101
Gene ExpressionFOXN1 [ NCBI-GEO ]   FOXN1 [ EBI - ARRAY_EXPRESS ]   FOXN1 [ SEEK ]   FOXN1 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8456
GTEX Portal (Tissue expression)FOXN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15353   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15353  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15353
Splice isoforms : SwissVarO15353
PhosPhoSitePlusO15353
Domaine pattern : Prosite (Expaxy)FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXN1
DMDM Disease mutations8456
Blocks (Seattle)FOXN1
SuperfamilyO15353
Human Protein AtlasENSG00000109101
Peptide AtlasO15353
HPRD02907
IPIIPI00006163   
Protein Interaction databases
DIP (DOE-UCLA)O15353
IntAct (EBI)O15353
FunCoupENSG00000109101
BioGRIDFOXN1
STRING (EMBL)FOXN1
ZODIACFOXN1
Ontologies - Pathways
QuickGOO15353
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  hair follicle development  T cell lineage commitment  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  defense response  epidermis development  animal organ morphogenesis  keratinocyte differentiation  positive regulation of epithelial cell differentiation  nail development  T cell homeostasis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  blood vessel morphogenesis  epithelial cell proliferation  positive regulation of hair follicle development  lymphoid lineage cell migration into thymus  thymus epithelium morphogenesis  regulation of positive thymic T cell selection  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  hair follicle development  T cell lineage commitment  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  defense response  epidermis development  animal organ morphogenesis  keratinocyte differentiation  positive regulation of epithelial cell differentiation  nail development  T cell homeostasis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  blood vessel morphogenesis  epithelial cell proliferation  positive regulation of hair follicle development  lymphoid lineage cell migration into thymus  thymus epithelium morphogenesis  regulation of positive thymic T cell selection  
NDEx NetworkFOXN1
Atlas of Cancer Signalling NetworkFOXN1
Wikipedia pathwaysFOXN1
Orthology - Evolution
OrthoDB8456
GeneTree (enSembl)ENSG00000109101
Phylogenetic Trees/Animal Genes : TreeFamFOXN1
HOVERGENO15353
HOGENOMO15353
Homologs : HomoloGeneFOXN1
Homology/Alignments : Family Browser (UCSC)FOXN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXN1
dbVarFOXN1
ClinVarFOXN1
1000_GenomesFOXN1 
Exome Variant ServerFOXN1
ExAC (Exome Aggregation Consortium)FOXN1 (select the gene name)
Genetic variants : HAPMAP8456
Genomic Variants (DGV)FOXN1 [DGVbeta]
DECIPHERFOXN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXN1 
Mutations
ICGC Data PortalFOXN1 
TCGA Data PortalFOXN1 
Broad Tumor PortalFOXN1
OASIS PortalFOXN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch FOXN1
DgiDB (Drug Gene Interaction Database)FOXN1
DoCM (Curated mutations)FOXN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXN1 (select a term)
intoGenFOXN1
Cancer3DFOXN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600838    601705   
Orphanet17819   
MedgenFOXN1
Genetic Testing Registry FOXN1
NextProtO15353 [Medical]
TSGene8456
GENETestsFOXN1
Target ValidationFOXN1
Huge Navigator FOXN1 [HugePedia]
snp3D : Map Gene to Disease8456
BioCentury BCIQFOXN1
ClinGenFOXN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8456
Chemical/Pharm GKB GenePA37368
Clinical trialFOXN1
Miscellaneous
canSAR (ICR)FOXN1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXN1
EVEXFOXN1
GoPubMedFOXN1
iHOPFOXN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:34:18 CEST 2017

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