Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXN2 (forkhead box N2)

Identity

Alias_namesHTLF
human T-cell leukemia virus enhancer factor
Other alias
HGNC (Hugo) FOXN2
LocusID (NCBI) 3344
Atlas_Id 40896
Location 2p16.3  [Link to chromosome band 2p16]
Location_base_pair Starts at 48314656 and ends at 48379295 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FOXN2 (2p16.3) / CXCR4 (2q22.1)FOXN2 (2p16.3) / PLB1 (2p23.2)FOXN2 (2p16.3) / SPTBN1 (2p16.2)
FOXN2 (2p16.3) / THAP4 (2q37.3)FOXN2 2p16.3 / PLB1 2p23.2FOXN2 2p16.3 / SPTBN1 2p16.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FOXN2   5281
Cards
Entrez_Gene (NCBI)FOXN2  3344  forkhead box N2
AliasesHTLF
GeneCards (Weizmann)FOXN2
Ensembl hg19 (Hinxton)ENSG00000170802 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170802 [Gene_View]  chr2:48314656-48379295 [Contig_View]  FOXN2 [Vega]
ICGC DataPortalENSG00000170802
TCGA cBioPortalFOXN2
AceView (NCBI)FOXN2
Genatlas (Paris)FOXN2
WikiGenes3344
SOURCE (Princeton)FOXN2
Genetics Home Reference (NIH)FOXN2
Genomic and cartography
GoldenPath hg38 (UCSC)FOXN2  -     chr2:48314656-48379295 +  2p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXN2  -     2p16.3   [Description]    (hg19-Feb_2009)
EnsemblFOXN2 - 2p16.3 [CytoView hg19]  FOXN2 - 2p16.3 [CytoView hg38]
Mapping of homologs : NCBIFOXN2 [Mapview hg19]  FOXN2 [Mapview hg38]
OMIM143089   
Gene and transcription
Genbank (Entrez)AA827684 AK123200 BC063305 BC069731 BQ025120
RefSeq transcript (Entrez)NM_002158
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXN2
Cluster EST : UnigeneHs.468478 [ NCBI ]
CGAP (NCI)Hs.468478
Alternative Splicing GalleryENSG00000170802
Gene ExpressionFOXN2 [ NCBI-GEO ]   FOXN2 [ EBI - ARRAY_EXPRESS ]   FOXN2 [ SEEK ]   FOXN2 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3344
GTEX Portal (Tissue expression)FOXN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32314   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32314  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32314
Splice isoforms : SwissVarP32314
PhosPhoSitePlusP32314
Domaine pattern : Prosite (Expaxy)FORK_HEAD_1 (PS00657)    FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    TF_fork_head_CS_1    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)   
Domain families : Pfam (NCBI)pfam00250   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXN2
DMDM Disease mutations3344
Blocks (Seattle)FOXN2
SuperfamilyP32314
Human Protein AtlasENSG00000170802
Peptide AtlasP32314
HPRD00882
IPIIPI00027968   IPI00413146   IPI00927950   IPI00894534   
Protein Interaction databases
DIP (DOE-UCLA)P32314
IntAct (EBI)P32314
FunCoupENSG00000170802
BioGRIDFOXN2
STRING (EMBL)FOXN2
ZODIACFOXN2
Ontologies - Pathways
QuickGOP32314
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleus  transcription, DNA-templated  cell differentiation  skeletal muscle cell differentiation  intracellular membrane-bounded organelle  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleus  transcription, DNA-templated  cell differentiation  skeletal muscle cell differentiation  intracellular membrane-bounded organelle  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  
NDEx NetworkFOXN2
Atlas of Cancer Signalling NetworkFOXN2
Wikipedia pathwaysFOXN2
Orthology - Evolution
OrthoDB3344
GeneTree (enSembl)ENSG00000170802
Phylogenetic Trees/Animal Genes : TreeFamFOXN2
HOVERGENP32314
HOGENOMP32314
Homologs : HomoloGeneFOXN2
Homology/Alignments : Family Browser (UCSC)FOXN2
Gene fusions - Rearrangements
Fusion : MitelmanFOXN2/PLB1 [2p16.3/2p23.2]  
Fusion : MitelmanFOXN2/SPTBN1 [2p16.3/2p16.2]  [t(2;2)(p16;p16)]  
Fusion: TCGAFOXN2 2p16.3 PLB1 2p23.2 HNSC
Fusion: TCGAFOXN2 2p16.3 SPTBN1 2p16.2 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXN2
dbVarFOXN2
ClinVarFOXN2
1000_GenomesFOXN2 
Exome Variant ServerFOXN2
ExAC (Exome Aggregation Consortium)FOXN2 (select the gene name)
Genetic variants : HAPMAP3344
Genomic Variants (DGV)FOXN2 [DGVbeta]
DECIPHERFOXN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXN2 
Mutations
ICGC Data PortalFOXN2 
TCGA Data PortalFOXN2 
Broad Tumor PortalFOXN2
OASIS PortalFOXN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOXN2
DgiDB (Drug Gene Interaction Database)FOXN2
DoCM (Curated mutations)FOXN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXN2 (select a term)
intoGenFOXN2
Cancer3DFOXN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM143089   
Orphanet
MedgenFOXN2
Genetic Testing Registry FOXN2
NextProtP32314 [Medical]
TSGene3344
GENETestsFOXN2
Target ValidationFOXN2
Huge Navigator FOXN2 [HugePedia]
snp3D : Map Gene to Disease3344
BioCentury BCIQFOXN2
ClinGenFOXN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3344
Chemical/Pharm GKB GenePA162388822
Clinical trialFOXN2
Miscellaneous
canSAR (ICR)FOXN2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXN2
EVEXFOXN2
GoPubMedFOXN2
iHOPFOXN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:34:19 CEST 2017

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