FOXN3 (forkhead box N3)

2007-07-01  

Identity

HGNC
LOCATION
14q31.3
LOCUSID
ALIAS
C14orf116,CHES1,PRO1635
FUSION GENES

Other Information

Locus ID:

NCBI: 1112
MIM: 602628
HGNC: 1928
Ensembl: ENSG00000053254

Variants:

dbSNP: 1112
ClinVar: 1112
TCGA: ENSG00000053254
COSMIC: FOXN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000053254ENST00000261302O00409
ENSG00000053254ENST00000261302A0A024R6I1
ENSG00000053254ENST00000345097O00409
ENSG00000053254ENST00000345097A0A024R6I1
ENSG00000053254ENST00000553353H0YJY0
ENSG00000053254ENST00000553840H0YJ54
ENSG00000053254ENST00000553904G3V4N5
ENSG00000053254ENST00000554005H0YJ94
ENSG00000053254ENST00000555034G3V5C7
ENSG00000053254ENST00000555353O00409
ENSG00000053254ENST00000555855G3V3A7
ENSG00000053254ENST00000556916H0YJ22
ENSG00000053254ENST00000557258O00409
ENSG00000053254ENST00000557572H0YJ43
ENSG00000053254ENST00000557718H0YJG3
ENSG00000053254ENST00000615335O00409

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
288056612017The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.32
169511492006Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response.28
231336272012MicroRNA-574-5p was pivotal for TLR9 signaling enhanced tumor progression via down-regulating checkpoint suppressor 1 in human lung cancer.25
260692512015A Systematic Approach to Defining the microRNA Landscape in Metastasis.24
161029182005CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor.19
179838022007Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.19
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
272592772016The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells.15
196095472009Metal-proteinase ADAM12, kinesin 14 and checkpoint suppressor 1 as new molecular markers of laryngeal carcinoma.14

Citation

Dessen P

FOXN3 (forkhead box N3)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47613/foxn3