Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FOXO6 (forkhead box O6)

Identity

Other alias-
HGNC (Hugo) FOXO6
LocusID (NCBI) 100132074
Atlas_Id 55618
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 41361931 and ends at 41383591 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FOXO6   24814
Cards
Entrez_Gene (NCBI)FOXO6  100132074  forkhead box O6
Aliases
GeneCards (Weizmann)FOXO6
Ensembl hg19 (Hinxton)ENSG00000204060 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204060 [Gene_View]  chr1:41361931-41383591 [Contig_View]  FOXO6 [Vega]
ICGC DataPortalENSG00000204060
TCGA cBioPortalFOXO6
AceView (NCBI)FOXO6
Genatlas (Paris)FOXO6
WikiGenes100132074
SOURCE (Princeton)FOXO6
Genetics Home Reference (NIH)FOXO6
Genomic and cartography
GoldenPath hg38 (UCSC)FOXO6  -     chr1:41361931-41383591 +  1p34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOXO6  -     1p34.2   [Description]    (hg19-Feb_2009)
EnsemblFOXO6 - 1p34.2 [CytoView hg19]  FOXO6 - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBIFOXO6 [Mapview hg19]  FOXO6 [Mapview hg38]
OMIM611457   
Gene and transcription
Genbank (Entrez)AI341823 AI361654
RefSeq transcript (Entrez)NM_001291281
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOXO6
Cluster EST : UnigeneHs.559677 [ NCBI ]
CGAP (NCI)Hs.559677
Alternative Splicing GalleryENSG00000204060
Gene ExpressionFOXO6 [ NCBI-GEO ]   FOXO6 [ EBI - ARRAY_EXPRESS ]   FOXO6 [ SEEK ]   FOXO6 [ MEM ]
Gene Expression Viewer (FireBrowse)FOXO6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100132074
GTEX Portal (Tissue expression)FOXO6
Human Protein AtlasENSG00000204060-FOXO6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MYZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MYZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MYZ6
Splice isoforms : SwissVarA8MYZ6
PhosPhoSitePlusA8MYZ6
Domaine pattern : Prosite (Expaxy)FORK_HEAD_2 (PS00658)    FORK_HEAD_3 (PS50039)   
Domains : Interpro (EBI)Fork_head_dom    FOXO-TAD    TF_fork_head_CS_2    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Forkhead (PF00250)    FOXO-TAD (PF16676)   
Domain families : Pfam (NCBI)pfam00250    pfam16676   
Domain families : Smart (EMBL)FH (SM00339)  
Conserved Domain (NCBI)FOXO6
DMDM Disease mutations100132074
Blocks (Seattle)FOXO6
SuperfamilyA8MYZ6
Human Protein Atlas [tissue]ENSG00000204060-FOXO6 [tissue]
Peptide AtlasA8MYZ6
IPIIPI01026050   IPI00397016   
Protein Interaction databases
DIP (DOE-UCLA)A8MYZ6
IntAct (EBI)A8MYZ6
FunCoupENSG00000204060
BioGRIDFOXO6
STRING (EMBL)FOXO6
ZODIACFOXO6
Ontologies - Pathways
QuickGOA8MYZ6
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of dendritic spine development  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of dendritic spine development  
Pathways : KEGGFoxO signaling pathway   
NDEx NetworkFOXO6
Atlas of Cancer Signalling NetworkFOXO6
Wikipedia pathwaysFOXO6
Orthology - Evolution
OrthoDB100132074
GeneTree (enSembl)ENSG00000204060
Phylogenetic Trees/Animal Genes : TreeFamFOXO6
HOVERGENA8MYZ6
HOGENOMA8MYZ6
Homologs : HomoloGeneFOXO6
Homology/Alignments : Family Browser (UCSC)FOXO6
Gene fusions - Rearrangements
Tumor Fusion PortalFOXO6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOXO6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOXO6
dbVarFOXO6
ClinVarFOXO6
1000_GenomesFOXO6 
Exome Variant ServerFOXO6
ExAC (Exome Aggregation Consortium)ENSG00000204060
GNOMAD BrowserENSG00000204060
Genetic variants : HAPMAP100132074
Genomic Variants (DGV)FOXO6 [DGVbeta]
DECIPHERFOXO6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOXO6 
Mutations
ICGC Data PortalFOXO6 
TCGA Data PortalFOXO6 
Broad Tumor PortalFOXO6
OASIS PortalFOXO6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFOXO6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFOXO6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOXO6
DgiDB (Drug Gene Interaction Database)FOXO6
DoCM (Curated mutations)FOXO6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOXO6 (select a term)
intoGenFOXO6
Cancer3DFOXO6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611457   
Orphanet
DisGeNETFOXO6
MedgenFOXO6
Genetic Testing Registry FOXO6
NextProtA8MYZ6 [Medical]
TSGene100132074
GENETestsFOXO6
Target ValidationFOXO6
Huge Navigator FOXO6 [HugePedia]
snp3D : Map Gene to Disease100132074
BioCentury BCIQFOXO6
ClinGenFOXO6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100132074
Chemical/Pharm GKB GenePA162388893
Clinical trialFOXO6
Miscellaneous
canSAR (ICR)FOXO6 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOXO6
EVEXFOXO6
GoPubMedFOXO6
iHOPFOXO6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:37:13 CET 2017

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