FOXP2 (forkhead box P2)

2003-05-01  

Identity

HGNC
LOCATION
7q31.1
LOCUSID
ALIAS
CAGH44,SPCH1,TNRC10
FUSION GENES

Other Information

Locus ID:

NCBI: 93986
MIM: 605317
HGNC: 13875
Ensembl: ENSG00000128573

Variants:

dbSNP: 93986
ClinVar: 93986
TCGA: ENSG00000128573
COSMIC: FOXP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128573ENST00000350908O15409
ENSG00000128573ENST00000360232O15409
ENSG00000128573ENST00000378237O15409
ENSG00000128573ENST00000390668Q8N6B5
ENSG00000128573ENST00000393489O15409
ENSG00000128573ENST00000393491Q0PRL4
ENSG00000128573ENST00000393494O15409
ENSG00000128573ENST00000393495A8MTU2
ENSG00000128573ENST00000393498A8MUV4
ENSG00000128573ENST00000403559O15409
ENSG00000128573ENST00000408937O15409
ENSG00000128573ENST00000408937X5D2H2
ENSG00000128573ENST00000412402O15409
ENSG00000128573ENST00000440349F8WDL6
ENSG00000128573ENST00000441290O15409
ENSG00000128573ENST00000452963C9JQP8
ENSG00000128573ENST00000462331Q75MZ5
ENSG00000128573ENST00000634411A0A0U1RQR8
ENSG00000128573ENST00000634623A0A0U1RQE0
ENSG00000128573ENST00000635109O15409
ENSG00000128573ENST00000635534A0A0U1RQY3
ENSG00000128573ENST00000635563A0A0U1RQE6
ENSG00000128573ENST00000635638A0A0U1RQM2
ENSG00000128573ENST00000638397A0A1W2PS63

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
115863592001A forkhead-domain gene is mutated in a severe speech and language disorder.411
121924082002Molecular evolution of FOXP2, a gene involved in speech and language.273
189873632008A functional genetic link between distinct developmental language disorders.235
189873632008A functional genetic link between distinct developmental language disorders.235
194908992009A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.173
193043382009FOXP2 as a molecular window into speech and language.154
199074932009Human-specific transcriptional regulation of CNS development genes by FOXP2.142
158772812005Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits.132
150566952004Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction.115
128761512003FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder.108

Citation

Dessen P

FOXP2 (forkhead box P2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40633/foxp2