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FPR2 (formyl peptide receptor 2)

Identity

Alias_namesFPRL1
formyl peptide receptor-like 1
Alias_symbol (synonym)LXA4R
HM63
FPRH2
FMLPX
FPR2A
FMLP-R-II
ALXR
Other aliasFPRH1
HGNC (Hugo) FPR2
LocusID (NCBI) 2358
Atlas_Id 50107
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 51761200 and ends at 51770526 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FPR2   3827
Cards
Entrez_Gene (NCBI)FPR2  2358  formyl peptide receptor 2
AliasesALXR; FMLP-R-II; FMLPX; FPR2A; 
FPRH1; FPRH2; FPRL1; HM63; LXA4R
GeneCards (Weizmann)FPR2
Ensembl hg19 (Hinxton)ENSG00000171049 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171049 [Gene_View]  chr19:51761200-51770526 [Contig_View]  FPR2 [Vega]
ICGC DataPortalENSG00000171049
TCGA cBioPortalFPR2
AceView (NCBI)FPR2
Genatlas (Paris)FPR2
WikiGenes2358
SOURCE (Princeton)FPR2
Genetics Home Reference (NIH)FPR2
Genomic and cartography
GoldenPath hg38 (UCSC)FPR2  -     chr19:51761200-51770526 +  19q13.41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FPR2  -     19q13.41   [Description]    (hg19-Feb_2009)
EnsemblFPR2 - 19q13.41 [CytoView hg19]  FPR2 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBIFPR2 [Mapview hg19]  FPR2 [Mapview hg38]
OMIM136538   
Gene and transcription
Genbank (Entrez)AF054013 AK290557 BC029125 BC071722 BM922150
RefSeq transcript (Entrez)NM_001005738 NM_001462
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FPR2
Cluster EST : UnigeneHs.99855 [ NCBI ]
CGAP (NCI)Hs.99855
Alternative Splicing GalleryENSG00000171049
Gene ExpressionFPR2 [ NCBI-GEO ]   FPR2 [ EBI - ARRAY_EXPRESS ]   FPR2 [ SEEK ]   FPR2 [ MEM ]
Gene Expression Viewer (FireBrowse)FPR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2358
GTEX Portal (Tissue expression)FPR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25090   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25090  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25090
Splice isoforms : SwissVarP25090
PhosPhoSitePlusP25090
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Formyl_pep_2/3_rcpt    Formyl_rcpt-rel    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)FPR2
DMDM Disease mutations2358
Blocks (Seattle)FPR2
SuperfamilyP25090
Human Protein AtlasENSG00000171049
Peptide AtlasP25090
HPRD00647
IPIIPI00012487   
Protein Interaction databases
DIP (DOE-UCLA)P25090
IntAct (EBI)P25090
FunCoupENSG00000171049
BioGRIDFPR2
STRING (EMBL)FPR2
ZODIACFPR2
Ontologies - Pathways
QuickGOP25090
Ontology : AmiGOcomplement receptor mediated signaling pathway  complement receptor activity  G-protein coupled receptor activity  N-formyl peptide receptor activity  plasma membrane  integral component of plasma membrane  movement of cell or subcellular component  chemotaxis  inflammatory response  cell adhesion  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  integral component of membrane  specific granule membrane  neutrophil degranulation  leukocyte migration  cell chemotaxis  tertiary granule membrane  ficolin-1-rich granule membrane  
Ontology : EGO-EBIcomplement receptor mediated signaling pathway  complement receptor activity  G-protein coupled receptor activity  N-formyl peptide receptor activity  plasma membrane  integral component of plasma membrane  movement of cell or subcellular component  chemotaxis  inflammatory response  cell adhesion  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  integral component of membrane  specific granule membrane  neutrophil degranulation  leukocyte migration  cell chemotaxis  tertiary granule membrane  ficolin-1-rich granule membrane  
Pathways : KEGGNeuroactive ligand-receptor interaction    Staphylococcus aureus infection   
NDEx NetworkFPR2
Atlas of Cancer Signalling NetworkFPR2
Wikipedia pathwaysFPR2
Orthology - Evolution
OrthoDB2358
GeneTree (enSembl)ENSG00000171049
Phylogenetic Trees/Animal Genes : TreeFamFPR2
HOVERGENP25090
HOGENOMP25090
Homologs : HomoloGeneFPR2
Homology/Alignments : Family Browser (UCSC)FPR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFPR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FPR2
dbVarFPR2
ClinVarFPR2
1000_GenomesFPR2 
Exome Variant ServerFPR2
ExAC (Exome Aggregation Consortium)FPR2 (select the gene name)
Genetic variants : HAPMAP2358
Genomic Variants (DGV)FPR2 [DGVbeta]
DECIPHERFPR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFPR2 
Mutations
ICGC Data PortalFPR2 
TCGA Data PortalFPR2 
Broad Tumor PortalFPR2
OASIS PortalFPR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFPR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFPR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FPR2
DgiDB (Drug Gene Interaction Database)FPR2
DoCM (Curated mutations)FPR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FPR2 (select a term)
intoGenFPR2
Cancer3DFPR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM136538   
Orphanet
MedgenFPR2
Genetic Testing Registry FPR2
NextProtP25090 [Medical]
TSGene2358
GENETestsFPR2
Target ValidationFPR2
Huge Navigator FPR2 [HugePedia]
snp3D : Map Gene to Disease2358
BioCentury BCIQFPR2
ClinGenFPR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2358
Chemical/Pharm GKB GenePA162388901
Clinical trialFPR2
Miscellaneous
canSAR (ICR)FPR2 (select the gene name)
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFPR2
EVEXFPR2
GoPubMedFPR2
iHOPFPR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:08:56 CEST 2017

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