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FRAT2 (FRAT2, WNT signaling pathway regulator)

Identity

Other alias-
HGNC (Hugo) FRAT2
LocusID (NCBI) 23401
Atlas_Id 465
Location 10q24.1  [Link to chromosome band 10q24]
Location_base_pair Starts at 97332497 and ends at 97334701 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FRAT2   16048
Cards
Entrez_Gene (NCBI)FRAT2  23401  FRAT2, WNT signaling pathway regulator
Aliases
GeneCards (Weizmann)FRAT2
Ensembl hg19 (Hinxton)ENSG00000181274 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181274 [Gene_View]  chr10:97332497-97334701 [Contig_View]  FRAT2 [Vega]
ICGC DataPortalENSG00000181274
TCGA cBioPortalFRAT2
AceView (NCBI)FRAT2
Genatlas (Paris)FRAT2
WikiGenes23401
SOURCE (Princeton)FRAT2
Genetics Home Reference (NIH)FRAT2
Genomic and cartography
GoldenPath hg38 (UCSC)FRAT2  -     chr10:97332497-97334701 -  10q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FRAT2  -     10q24.1   [Description]    (hg19-Feb_2009)
EnsemblFRAT2 - 10q24.1 [CytoView hg19]  FRAT2 - 10q24.1 [CytoView hg38]
Mapping of homologs : NCBIFRAT2 [Mapview hg19]  FRAT2 [Mapview hg38]
OMIM605006   
Gene and transcription
Genbank (Entrez)AB045118 AF062739 BC020165 BT009770 BU675503
RefSeq transcript (Entrez)NM_012083
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FRAT2
Cluster EST : UnigeneHs.140720 [ NCBI ]
CGAP (NCI)Hs.140720
Alternative Splicing GalleryENSG00000181274
Gene ExpressionFRAT2 [ NCBI-GEO ]   FRAT2 [ EBI - ARRAY_EXPRESS ]   FRAT2 [ SEEK ]   FRAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)FRAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23401
GTEX Portal (Tissue expression)FRAT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75474   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75474  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75474
Splice isoforms : SwissVarO75474
PhosPhoSitePlusO75474
Domains : Interpro (EBI)GSK3-bd   
Domain families : Pfam (Sanger)GSK-3_bind (PF05350)   
Domain families : Pfam (NCBI)pfam05350   
Conserved Domain (NCBI)FRAT2
DMDM Disease mutations23401
Blocks (Seattle)FRAT2
SuperfamilyO75474
Human Protein AtlasENSG00000181274
Peptide AtlasO75474
HPRD05419
IPIIPI00289578   IPI00984076   
Protein Interaction databases
DIP (DOE-UCLA)O75474
IntAct (EBI)O75474
FunCoupENSG00000181274
BioGRIDFRAT2
STRING (EMBL)FRAT2
ZODIACFRAT2
Ontologies - Pathways
QuickGOO75474
Ontology : AmiGOmolecular_function  cellular_component  cytosol  multicellular organism development  cell proliferation  beta-catenin destruction complex disassembly  
Ontology : EGO-EBImolecular_function  cellular_component  cytosol  multicellular organism development  cell proliferation  beta-catenin destruction complex disassembly  
Pathways : KEGGWnt signaling pathway   
NDEx NetworkFRAT2
Atlas of Cancer Signalling NetworkFRAT2
Wikipedia pathwaysFRAT2
Orthology - Evolution
OrthoDB23401
GeneTree (enSembl)ENSG00000181274
Phylogenetic Trees/Animal Genes : TreeFamFRAT2
HOVERGENO75474
HOGENOMO75474
Homologs : HomoloGeneFRAT2
Homology/Alignments : Family Browser (UCSC)FRAT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFRAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FRAT2
dbVarFRAT2
ClinVarFRAT2
1000_GenomesFRAT2 
Exome Variant ServerFRAT2
ExAC (Exome Aggregation Consortium)FRAT2 (select the gene name)
Genetic variants : HAPMAP23401
Genomic Variants (DGV)FRAT2 [DGVbeta]
DECIPHERFRAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFRAT2 
Mutations
ICGC Data PortalFRAT2 
TCGA Data PortalFRAT2 
Broad Tumor PortalFRAT2
OASIS PortalFRAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFRAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFRAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FRAT2
DgiDB (Drug Gene Interaction Database)FRAT2
DoCM (Curated mutations)FRAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FRAT2 (select a term)
intoGenFRAT2
Cancer3DFRAT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605006   
Orphanet
MedgenFRAT2
Genetic Testing Registry FRAT2
NextProtO75474 [Medical]
TSGene23401
GENETestsFRAT2
Huge Navigator FRAT2 [HugePedia]
snp3D : Map Gene to Disease23401
BioCentury BCIQFRAT2
ClinGenFRAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23401
Chemical/Pharm GKB GenePA28362
Clinical trialFRAT2
Miscellaneous
canSAR (ICR)FRAT2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFRAT2
EVEXFRAT2
GoPubMedFRAT2
iHOPFRAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:16:26 CEST 2017

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