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FREM1 (FRAS1 related extracellular matrix 1)

Identity

Alias_namesC9orf154
chromosome 9 open reading frame 154
Alias_symbol (synonym)FLJ25461
C9orf145
C9orf143
DKFZp686M16108
TILRR
Other aliasBNAR
MOTA
TRIGNO2
HGNC (Hugo) FREM1
LocusID (NCBI) 158326
Atlas_Id 63584
Location 9p22.3  [Link to chromosome band 9p22]
Location_base_pair Starts at 14734666 and ends at 14779533 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FREM1 (9p22.3) / FREM1 (9p22.3)NFIB (9p23) / FREM1 (9p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FREM1   23399
Cards
Entrez_Gene (NCBI)FREM1  158326  FRAS1 related extracellular matrix 1
AliasesBNAR; C9orf143; C9orf145; C9orf154; 
MOTA; TILRR; TRIGNO2
GeneCards (Weizmann)FREM1
Ensembl hg19 (Hinxton)ENSG00000164946 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164946 [Gene_View]  chr9:14734666-14779533 [Contig_View]  FREM1 [Vega]
ICGC DataPortalENSG00000164946
TCGA cBioPortalFREM1
AceView (NCBI)FREM1
Genatlas (Paris)FREM1
WikiGenes158326
SOURCE (Princeton)FREM1
Genetics Home Reference (NIH)FREM1
Genomic and cartography
GoldenPath hg38 (UCSC)FREM1  -     chr9:14734666-14779533 -  9p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FREM1  -     9p22.3   [Description]    (hg19-Feb_2009)
EnsemblFREM1 - 9p22.3 [CytoView hg19]  FREM1 - 9p22.3 [CytoView hg38]
Mapping of homologs : NCBIFREM1 [Mapview hg19]  FREM1 [Mapview hg38]
OMIM248450   608944   608980   614485   
Gene and transcription
Genbank (Entrez)AB160987 AK054690 AK058190 BC031064 BC172226
RefSeq transcript (Entrez)NM_001177704 NM_144966
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FREM1
Cluster EST : UnigeneHs.50850 [ NCBI ]
CGAP (NCI)Hs.50850
Alternative Splicing GalleryENSG00000164946
Gene ExpressionFREM1 [ NCBI-GEO ]   FREM1 [ EBI - ARRAY_EXPRESS ]   FREM1 [ SEEK ]   FREM1 [ MEM ]
Gene Expression Viewer (FireBrowse)FREM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)158326
GTEX Portal (Tissue expression)FREM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5H8C1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5H8C1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5H8C1
Splice isoforms : SwissVarQ5H8C1
PhosPhoSitePlusQ5H8C1
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    Calx_beta    CTDL_fold    FREM1   
Domain families : Pfam (Sanger)Calx-beta (PF03160)    Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam03160    pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)FREM1
DMDM Disease mutations158326
Blocks (Seattle)FREM1
SuperfamilyQ5H8C1
Human Protein AtlasENSG00000164946
Peptide AtlasQ5H8C1
HPRD09865
IPIIPI00477820   IPI00645359   IPI00186984   IPI00927186   IPI00922794   
Protein Interaction databases
DIP (DOE-UCLA)Q5H8C1
IntAct (EBI)Q5H8C1
FunCoupENSG00000164946
BioGRIDFREM1
STRING (EMBL)FREM1
ZODIACFREM1
Ontologies - Pathways
QuickGOQ5H8C1
Ontology : AmiGObasement membrane  cell communication  cell-matrix adhesion  integral component of membrane  carbohydrate binding  metal ion binding  craniofacial suture morphogenesis  
Ontology : EGO-EBIbasement membrane  cell communication  cell-matrix adhesion  integral component of membrane  carbohydrate binding  metal ion binding  craniofacial suture morphogenesis  
NDEx NetworkFREM1
Atlas of Cancer Signalling NetworkFREM1
Wikipedia pathwaysFREM1
Orthology - Evolution
OrthoDB158326
GeneTree (enSembl)ENSG00000164946
Phylogenetic Trees/Animal Genes : TreeFamFREM1
HOVERGENQ5H8C1
HOGENOMQ5H8C1
Homologs : HomoloGeneFREM1
Homology/Alignments : Family Browser (UCSC)FREM1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFREM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FREM1
dbVarFREM1
ClinVarFREM1
1000_GenomesFREM1 
Exome Variant ServerFREM1
ExAC (Exome Aggregation Consortium)FREM1 (select the gene name)
Genetic variants : HAPMAP158326
Genomic Variants (DGV)FREM1 [DGVbeta]
DECIPHERFREM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFREM1 
Mutations
ICGC Data PortalFREM1 
TCGA Data PortalFREM1 
Broad Tumor PortalFREM1
OASIS PortalFREM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFREM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFREM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch FREM1
DgiDB (Drug Gene Interaction Database)FREM1
DoCM (Curated mutations)FREM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FREM1 (select a term)
intoGenFREM1
Cancer3DFREM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM248450    608944    608980    614485   
Orphanet2478    2983    18829    12163   
MedgenFREM1
Genetic Testing Registry FREM1
NextProtQ5H8C1 [Medical]
TSGene158326
GENETestsFREM1
Target ValidationFREM1
Huge Navigator FREM1 [HugePedia]
snp3D : Map Gene to Disease158326
BioCentury BCIQFREM1
ClinGenFREM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD158326
Chemical/Pharm GKB GenePA134892147
Clinical trialFREM1
Miscellaneous
canSAR (ICR)FREM1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFREM1
EVEXFREM1
GoPubMedFREM1
iHOPFREM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:08:54 CEST 2017

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