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FREM2 (FRAS1 related extracellular matrix protein 2)

Identity

Alias_symbol (synonym)DKFZp686J0811
Other alias-
HGNC (Hugo) FREM2
LocusID (NCBI) 341640
Atlas_Id 52844
Location 13q13.3  [Link to chromosome band 13q13]
Location_base_pair Starts at 38687036 and ends at 38887130 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FREM2 (13q13.3) / MTRF1 (13q14.11)FREM2 (13q13.3) / QKI (6q26)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FREM2   25396
Cards
Entrez_Gene (NCBI)FREM2  341640  FRAS1 related extracellular matrix protein 2
Aliases
GeneCards (Weizmann)FREM2
Ensembl hg19 (Hinxton)ENSG00000150893 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000150893 [Gene_View]  chr13:38687036-38887130 [Contig_View]  FREM2 [Vega]
ICGC DataPortalENSG00000150893
TCGA cBioPortalFREM2
AceView (NCBI)FREM2
Genatlas (Paris)FREM2
WikiGenes341640
SOURCE (Princeton)FREM2
Genetics Home Reference (NIH)FREM2
Genomic and cartography
GoldenPath hg38 (UCSC)FREM2  -     chr13:38687036-38887130 +  13q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FREM2  -     13q13.3   [Description]    (hg19-Feb_2009)
EnsemblFREM2 - 13q13.3 [CytoView hg19]  FREM2 - 13q13.3 [CytoView hg38]
Mapping of homologs : NCBIFREM2 [Mapview hg19]  FREM2 [Mapview hg38]
OMIM219000   608945   
Gene and transcription
Genbank (Entrez)AK127571 AK127633 AL708377 BC172230 BG991015
RefSeq transcript (Entrez)NM_207361
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FREM2
Cluster EST : UnigeneHs.253994 [ NCBI ]
CGAP (NCI)Hs.253994
Alternative Splicing GalleryENSG00000150893
Gene ExpressionFREM2 [ NCBI-GEO ]   FREM2 [ EBI - ARRAY_EXPRESS ]   FREM2 [ SEEK ]   FREM2 [ MEM ]
Gene Expression Viewer (FireBrowse)FREM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)341640
GTEX Portal (Tissue expression)FREM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SZK8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SZK8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SZK8
Splice isoforms : SwissVarQ5SZK8
PhosPhoSitePlusQ5SZK8
Domains : Interpro (EBI)Calx_beta   
Domain families : Pfam (Sanger)Calx-beta (PF03160)   
Domain families : Pfam (NCBI)pfam03160   
Domain families : Smart (EMBL)Calx_beta (SM00237)  
Conserved Domain (NCBI)FREM2
DMDM Disease mutations341640
Blocks (Seattle)FREM2
SuperfamilyQ5SZK8
Human Protein AtlasENSG00000150893
Peptide AtlasQ5SZK8
HPRD10602
IPIIPI00180707   IPI00640805   
Protein Interaction databases
DIP (DOE-UCLA)Q5SZK8
IntAct (EBI)Q5SZK8
FunCoupENSG00000150893
BioGRIDFREM2
STRING (EMBL)FREM2
ZODIACFREM2
Ontologies - Pathways
QuickGOQ5SZK8
Ontology : AmiGOmorphogenesis of an epithelium  basement membrane  plasma membrane  cell communication  cell adhesion  heart development  integral component of membrane  metal ion binding  inner ear development  extracellular exosome  
Ontology : EGO-EBImorphogenesis of an epithelium  basement membrane  plasma membrane  cell communication  cell adhesion  heart development  integral component of membrane  metal ion binding  inner ear development  extracellular exosome  
NDEx NetworkFREM2
Atlas of Cancer Signalling NetworkFREM2
Wikipedia pathwaysFREM2
Orthology - Evolution
OrthoDB341640
GeneTree (enSembl)ENSG00000150893
Phylogenetic Trees/Animal Genes : TreeFamFREM2
HOVERGENQ5SZK8
HOGENOMQ5SZK8
Homologs : HomoloGeneFREM2
Homology/Alignments : Family Browser (UCSC)FREM2
Gene fusions - Rearrangements
Fusion : MitelmanFREM2/MTRF1 [13q13.3/13q14.11]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFREM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FREM2
dbVarFREM2
ClinVarFREM2
1000_GenomesFREM2 
Exome Variant ServerFREM2
ExAC (Exome Aggregation Consortium)FREM2 (select the gene name)
Genetic variants : HAPMAP341640
Genomic Variants (DGV)FREM2 [DGVbeta]
DECIPHERFREM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFREM2 
Mutations
ICGC Data PortalFREM2 
TCGA Data PortalFREM2 
Broad Tumor PortalFREM2
OASIS PortalFREM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFREM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFREM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FREM2
DgiDB (Drug Gene Interaction Database)FREM2
DoCM (Curated mutations)FREM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FREM2 (select a term)
intoGenFREM2
Cancer3DFREM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM219000    608945   
Orphanet1046    12163   
MedgenFREM2
Genetic Testing Registry FREM2
NextProtQ5SZK8 [Medical]
TSGene341640
GENETestsFREM2
Target ValidationFREM2
Huge Navigator FREM2 [HugePedia]
snp3D : Map Gene to Disease341640
BioCentury BCIQFREM2
ClinGenFREM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD341640
Chemical/Pharm GKB GenePA134930862
Clinical trialFREM2
Miscellaneous
canSAR (ICR)FREM2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFREM2
EVEXFREM2
GoPubMedFREM2
iHOPFREM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:08:58 CEST 2017

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