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FRG2B (FSHD region gene 2 family member B)

Identity

Alias (NCBI)-
HGNC (Hugo) FRG2B
HGNC Previous nameFSHD region gene 2 family, member B
LocusID (NCBI) 441581
Atlas_Id 63588
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 133623895 and ends at 133626795 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(4;10)(q35;q26) DUX4/FRG2B
t(4;10)(q35;q26) DUX4/FRG2B


External links

 

Nomenclature
HGNC (Hugo)FRG2B   33518
Cards
Entrez_Gene (NCBI)FRG2B    FSHD region gene 2 family member B
Aliases
GeneCards (Weizmann)FRG2B
Ensembl hg19 (Hinxton)ENSG00000225899 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000225899 [Gene_View]  ENSG00000225899 [Sequence]  chr10:133623895-133626795 [Contig_View]  FRG2B [Vega]
ICGC DataPortalENSG00000225899
TCGA cBioPortalFRG2B
AceView (NCBI)FRG2B
Genatlas (Paris)FRG2B
SOURCE (Princeton)FRG2B
Genetics Home Reference (NIH)FRG2B
Genomic and cartography
GoldenPath hg38 (UCSC)FRG2B  -     chr10:133623895-133626795 -  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FRG2B  -     10q26.3   [Description]    (hg19-Feb_2009)
GoldenPathFRG2B - 10q26.3 [CytoView hg19]  FRG2B - 10q26.3 [CytoView hg38]
ImmunoBaseENSG00000225899
Genome Data Viewer NCBIFRG2B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AY744466
RefSeq transcript (Entrez)NM_001080998
Consensus coding sequences : CCDS (NCBI)FRG2B
Gene ExpressionFRG2B [ NCBI-GEO ]   FRG2B [ EBI - ARRAY_EXPRESS ]   FRG2B [ SEEK ]   FRG2B [ MEM ]
Gene Expression Viewer (FireBrowse)FRG2B [ Firebrowse - Broad ]
GenevisibleExpression of FRG2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)441581
GTEX Portal (Tissue expression)FRG2B
Human Protein AtlasENSG00000225899-FRG2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QU4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QU4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QU4
PhosPhoSitePlusQ96QU4
Domains : Interpro (EBI)FRG2   
Domain families : Pfam (Sanger)FRG2 (PF15315)   
Domain families : Pfam (NCBI)pfam15315   
Conserved Domain (NCBI)FRG2B
SuperfamilyQ96QU4
AlphaFold pdb e-kbQ96QU4   
Human Protein Atlas [tissue]ENSG00000225899-FRG2B [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q96QU4
IntAct (EBI)Q96QU4
BioGRIDFRG2B
STRING (EMBL)FRG2B
ZODIACFRG2B
Ontologies - Pathways
QuickGOQ96QU4
Ontology : AmiGOnucleus  
Ontology : EGO-EBInucleus  
NDEx NetworkFRG2B
Atlas of Cancer Signalling NetworkFRG2B
Wikipedia pathwaysFRG2B
Orthology - Evolution
OrthoDB441581
GeneTree (enSembl)ENSG00000225899
Phylogenetic Trees/Animal Genes : TreeFamFRG2B
Homologs : HomoloGeneFRG2B
Homology/Alignments : Family Browser (UCSC)FRG2B
Gene fusions - Rearrangements
Fusion : QuiverFRG2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFRG2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FRG2B
dbVarFRG2B
ClinVarFRG2B
MonarchFRG2B
1000_GenomesFRG2B 
Exome Variant ServerFRG2B
GNOMAD BrowserENSG00000225899
Varsome BrowserFRG2B
ACMGFRG2B variants
VarityQ96QU4
Genomic Variants (DGV)FRG2B [DGVbeta]
DECIPHERFRG2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFRG2B 
Mutations
ICGC Data PortalFRG2B 
TCGA Data PortalFRG2B 
Broad Tumor PortalFRG2B
OASIS PortalFRG2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFRG2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFRG2B
Mutations and Diseases : HGMDFRG2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFRG2B
DgiDB (Drug Gene Interaction Database)FRG2B
DoCM (Curated mutations)FRG2B
CIViC (Clinical Interpretations of Variants in Cancer)FRG2B
Cancer3DFRG2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETFRG2B
MedgenFRG2B
Genetic Testing Registry FRG2B
NextProtQ96QU4 [Medical]
GENETestsFRG2B
Target ValidationFRG2B
Huge Navigator FRG2B [HugePedia]
ClinGenFRG2B
Clinical trials, drugs, therapy
MyCancerGenomeFRG2B
Protein Interactions : CTDFRG2B
Pharm GKB GenePA162388920
PharosQ96QU4
Clinical trialFRG2B
Miscellaneous
canSAR (ICR)FRG2B
HarmonizomeFRG2B
DataMed IndexFRG2B
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFRG2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:50:53 CEST 2021

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