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FRMD4B (FERM domain containing 4B)

Identity

Alias_symbol (synonym)KIAA1013
GRSP1
Other alias6030440G05Rik
HGNC (Hugo) FRMD4B
LocusID (NCBI) 23150
Atlas_Id 63593
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 69168783 and ends at 69386304 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARL13B (3q11.1) / FRMD4B (3p14.1)FRMD4B (3p14.1) / NUP88 (17p13.2)FRMD4B (3p14.1) / PPP2R3A (3q22.2)
FRMD4B (3p14.1) / SLC22A17 (14q11.2)MFHAS1 (8p23.1) / FRMD4B (3p14.1)UBA3 (3p14.1) / FRMD4B (3p14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FRMD4B   24886
Cards
Entrez_Gene (NCBI)FRMD4B  23150  FERM domain containing 4B
Aliases6030440G05Rik; GRSP1
GeneCards (Weizmann)FRMD4B
Ensembl hg19 (Hinxton)ENSG00000114541 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114541 [Gene_View]  chr3:69168783-69386304 [Contig_View]  FRMD4B [Vega]
ICGC DataPortalENSG00000114541
TCGA cBioPortalFRMD4B
AceView (NCBI)FRMD4B
Genatlas (Paris)FRMD4B
WikiGenes23150
SOURCE (Princeton)FRMD4B
Genetics Home Reference (NIH)FRMD4B
Genomic and cartography
GoldenPath hg38 (UCSC)FRMD4B  -     chr3:69168783-69386304 -  3p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FRMD4B  -     3p14.1   [Description]    (hg19-Feb_2009)
EnsemblFRMD4B - 3p14.1 [CytoView hg19]  FRMD4B - 3p14.1 [CytoView hg38]
Mapping of homologs : NCBIFRMD4B [Mapview hg19]  FRMD4B [Mapview hg38]
OMIM617467   
Gene and transcription
Genbank (Entrez)AB023230 AK000244 AK024086 AK091076 AK295045
RefSeq transcript (Entrez)NM_015123
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FRMD4B
Cluster EST : UnigeneHs.709671 [ NCBI ]
CGAP (NCI)Hs.709671
Alternative Splicing GalleryENSG00000114541
Gene ExpressionFRMD4B [ NCBI-GEO ]   FRMD4B [ EBI - ARRAY_EXPRESS ]   FRMD4B [ SEEK ]   FRMD4B [ MEM ]
Gene Expression Viewer (FireBrowse)FRMD4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23150
GTEX Portal (Tissue expression)FRMD4B
Human Protein AtlasENSG00000114541-FRMD4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2L6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2L6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2L6
Splice isoforms : SwissVarQ9Y2L6
PhosPhoSitePlusQ9Y2L6
Domaine pattern : Prosite (Expaxy)FERM_2 (PS00661)    FERM_3 (PS50057)   
Domains : Interpro (EBI)Band_41_domain    DUF3338    FERM/acyl-CoA-bd_prot_3-hlx    FERM_central    FERM_CS    FERM_domain    FERM_N    FERM_PH-like_C    PH_dom-like    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)DUF3338 (PF11819)    FERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)   
Domain families : Pfam (NCBI)pfam11819    pfam09380    pfam00373    pfam09379   
Domain families : Smart (EMBL)B41 (SM00295)  FERM_C (SM01196)  
Conserved Domain (NCBI)FRMD4B
DMDM Disease mutations23150
Blocks (Seattle)FRMD4B
SuperfamilyQ9Y2L6
Human Protein Atlas [tissue]ENSG00000114541-FRMD4B [tissue]
Peptide AtlasQ9Y2L6
IPIIPI00852848   IPI01008848   IPI00217948   IPI00947315   IPI00447719   IPI00947148   IPI00796875   IPI00946601   IPI00946418   IPI00946267   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2L6
IntAct (EBI)Q9Y2L6
FunCoupENSG00000114541
BioGRIDFRMD4B
STRING (EMBL)FRMD4B
ZODIACFRMD4B
Ontologies - Pathways
QuickGOQ9Y2L6
Ontology : AmiGOruffle  extracellular space  cytoplasm  cytoskeleton  establishment of epithelial cell polarity  
Ontology : EGO-EBIruffle  extracellular space  cytoplasm  cytoskeleton  establishment of epithelial cell polarity  
NDEx NetworkFRMD4B
Atlas of Cancer Signalling NetworkFRMD4B
Wikipedia pathwaysFRMD4B
Orthology - Evolution
OrthoDB23150
GeneTree (enSembl)ENSG00000114541
Phylogenetic Trees/Animal Genes : TreeFamFRMD4B
HOVERGENQ9Y2L6
HOGENOMQ9Y2L6
Homologs : HomoloGeneFRMD4B
Homology/Alignments : Family Browser (UCSC)FRMD4B
Gene fusions - Rearrangements
Fusion: Tumor Portal FRMD4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFRMD4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FRMD4B
dbVarFRMD4B
ClinVarFRMD4B
1000_GenomesFRMD4B 
Exome Variant ServerFRMD4B
ExAC (Exome Aggregation Consortium)ENSG00000114541
GNOMAD BrowserENSG00000114541
Genetic variants : HAPMAP23150
Genomic Variants (DGV)FRMD4B [DGVbeta]
DECIPHERFRMD4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFRMD4B 
Mutations
ICGC Data PortalFRMD4B 
TCGA Data PortalFRMD4B 
Broad Tumor PortalFRMD4B
OASIS PortalFRMD4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFRMD4B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFRMD4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FRMD4B
DgiDB (Drug Gene Interaction Database)FRMD4B
DoCM (Curated mutations)FRMD4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FRMD4B (select a term)
intoGenFRMD4B
Cancer3DFRMD4B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617467   
Orphanet
MedgenFRMD4B
Genetic Testing Registry FRMD4B
NextProtQ9Y2L6 [Medical]
TSGene23150
GENETestsFRMD4B
Target ValidationFRMD4B
Huge Navigator FRMD4B [HugePedia]
snp3D : Map Gene to Disease23150
BioCentury BCIQFRMD4B
ClinGenFRMD4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23150
Chemical/Pharm GKB GenePA128394605
Clinical trialFRMD4B
Miscellaneous
canSAR (ICR)FRMD4B (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFRMD4B
EVEXFRMD4B
GoPubMedFRMD4B
iHOPFRMD4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:48:23 CET 2017

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