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FRMD6 (FERM domain containing 6)

Identity

Alias (NCBI)C14orf31
EX1
Willin
c14_5320
HGNC (Hugo) FRMD6
HGNC Alias symbMGC17921
willin
EX1
HGNC Alias nameexpanded homolog
HGNC Previous nameC14orf31
HGNC Previous namechromosome 14 open reading frame 31
LocusID (NCBI) 122786
Atlas_Id 52707
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 51651910 and ends at 51730726 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C1orf210 (1p34.2) / FRMD6 (14q22.1)FRMD6 (14q22.1) / BPIFB1 (20q11.21)FRMD6 (14q22.1) / CEP295 (11q21)
FRMD6 (14q22.1) / RTN4 (2p16.1)FRMD6 (14q22.1) / SCFD1 (14q12)FRMD6 14q22.1 / BPIFB1 20q11.21
FRMD6 14q22.1 / RTN4 2p16.1FRMD6 14q22.1 / SCFD1 14q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FRMD6   19839
Cards
Entrez_Gene (NCBI)FRMD6    FERM domain containing 6
AliasesC14orf31; EX1; Willin; c14_5320
GeneCards (Weizmann)FRMD6
Ensembl hg19 (Hinxton)ENSG00000139926 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139926 [Gene_View]  ENSG00000139926 [Sequence]  chr14:51651910-51730726 [Contig_View]  FRMD6 [Vega]
ICGC DataPortalENSG00000139926
TCGA cBioPortalFRMD6
AceView (NCBI)FRMD6
Genatlas (Paris)FRMD6
SOURCE (Princeton)FRMD6
Genetics Home Reference (NIH)FRMD6
Genomic and cartography
GoldenPath hg38 (UCSC)FRMD6  -     chr14:51651910-51730726 +  14q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FRMD6  -     14q22.1   [Description]    (hg19-Feb_2009)
GoldenPathFRMD6 - 14q22.1 [CytoView hg19]  FRMD6 - 14q22.1 [CytoView hg38]
ImmunoBaseENSG00000139926
Genome Data Viewer NCBIFRMD6 [Mapview hg19]  
OMIM614555   
Gene and transcription
Genbank (Entrez)AK021747 AK055545 AK126521 AK129995 AK315764
RefSeq transcript (Entrez)NM_001042481 NM_001267046 NM_001267047 NM_152330
Consensus coding sequences : CCDS (NCBI)FRMD6
Gene ExpressionFRMD6 [ NCBI-GEO ]   FRMD6 [ EBI - ARRAY_EXPRESS ]   FRMD6 [ SEEK ]   FRMD6 [ MEM ]
Gene Expression Viewer (FireBrowse)FRMD6 [ Firebrowse - Broad ]
GenevisibleExpression of FRMD6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122786
GTEX Portal (Tissue expression)FRMD6
Human Protein AtlasENSG00000139926-FRMD6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NE9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NE9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NE9
PhosPhoSitePlusQ96NE9
Domaine pattern : Prosite (Expaxy)FERM_3 (PS50057)   
Domains : Interpro (EBI)Band_41_domain    FERM/acyl-CoA-bd_prot_sf    FERM_2    FERM_central    FERM_domain    FERM_N    FERM_PH-like_C    FRMD6    FRMD6-FERM_C    PH-like_dom_sf    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)FERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)   
Domain families : Pfam (NCBI)pfam09380    pfam00373    pfam09379   
Domain families : Smart (EMBL)B41 (SM00295)  FERM_C (SM01196)  
Conserved Domain (NCBI)FRMD6
SuperfamilyQ96NE9
AlphaFold pdb e-kbQ96NE9   
Human Protein Atlas [tissue]ENSG00000139926-FRMD6 [tissue]
HPRD12646
Protein Interaction databases
DIP (DOE-UCLA)Q96NE9
IntAct (EBI)Q96NE9
BioGRIDFRMD6
STRING (EMBL)FRMD6
ZODIACFRMD6
Ontologies - Pathways
QuickGOQ96NE9
Ontology : AmiGOprotein binding  cytoplasm  cytoskeleton  plasma membrane  actomyosin structure organization  
Ontology : EGO-EBIprotein binding  cytoplasm  cytoskeleton  plasma membrane  actomyosin structure organization  
Pathways : KEGGHippo signaling pathway   
NDEx NetworkFRMD6
Atlas of Cancer Signalling NetworkFRMD6
Wikipedia pathwaysFRMD6
Orthology - Evolution
OrthoDB122786
GeneTree (enSembl)ENSG00000139926
Phylogenetic Trees/Animal Genes : TreeFamFRMD6
Homologs : HomoloGeneFRMD6
Homology/Alignments : Family Browser (UCSC)FRMD6
Gene fusions - Rearrangements
Fusion : MitelmanFRMD6/BPIFB1 [14q22.1/20q11.21]  
Fusion : MitelmanFRMD6/RTN4 [14q22.1/2p16.1]  
Fusion : MitelmanFRMD6/SCFD1 [14q22.1/14q12]  
Fusion : QuiverFRMD6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFRMD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FRMD6
dbVarFRMD6
ClinVarFRMD6
MonarchFRMD6
1000_GenomesFRMD6 
Exome Variant ServerFRMD6
GNOMAD BrowserENSG00000139926
Varsome BrowserFRMD6
ACMGFRMD6 variants
VarityQ96NE9
Genomic Variants (DGV)FRMD6 [DGVbeta]
DECIPHERFRMD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFRMD6 
Mutations
ICGC Data PortalFRMD6 
TCGA Data PortalFRMD6 
Broad Tumor PortalFRMD6
OASIS PortalFRMD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFRMD6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFRMD6
Mutations and Diseases : HGMDFRMD6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFRMD6
DgiDB (Drug Gene Interaction Database)FRMD6
DoCM (Curated mutations)FRMD6
CIViC (Clinical Interpretations of Variants in Cancer)FRMD6
Cancer3DFRMD6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614555   
Orphanet
DisGeNETFRMD6
MedgenFRMD6
Genetic Testing Registry FRMD6
NextProtQ96NE9 [Medical]
GENETestsFRMD6
Target ValidationFRMD6
Huge Navigator FRMD6 [HugePedia]
ClinGenFRMD6
Clinical trials, drugs, therapy
MyCancerGenomeFRMD6
Protein Interactions : CTDFRMD6
Pharm GKB GenePA134913028
PharosQ96NE9
Clinical trialFRMD6
Miscellaneous
canSAR (ICR)FRMD6
HarmonizomeFRMD6
DataMed IndexFRMD6
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFRMD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:09:58 CEST 2021

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