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FRRS1 (ferric chelate reductase 1)

Identity

Alias_namesSDFR2
stromal cell derived factor receptor 2 homolog (mouse)
ferric-chelate reductase 1
Alias_symbol (synonym)SDR2
Other alias
HGNC (Hugo) FRRS1
LocusID (NCBI) 391059
Atlas_Id 63604
Location 1p21.2  [Link to chromosome band 1p21]
Location_base_pair Starts at 99708703 and ends at 99765793 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FRRS1   27622
Cards
Entrez_Gene (NCBI)FRRS1  391059  ferric chelate reductase 1
AliasesSDFR2; SDR2
GeneCards (Weizmann)FRRS1
Ensembl hg19 (Hinxton)ENSG00000156869 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156869 [Gene_View]  chr1:99708703-99765793 [Contig_View]  FRRS1 [Vega]
ICGC DataPortalENSG00000156869
TCGA cBioPortalFRRS1
AceView (NCBI)FRRS1
Genatlas (Paris)FRRS1
WikiGenes391059
SOURCE (Princeton)FRRS1
Genetics Home Reference (NIH)FRRS1
Genomic and cartography
GoldenPath hg38 (UCSC)FRRS1  -     chr1:99708703-99765793 -  1p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FRRS1  -     1p21.2   [Description]    (hg19-Feb_2009)
EnsemblFRRS1 - 1p21.2 [CytoView hg19]  FRRS1 - 1p21.2 [CytoView hg38]
Mapping of homologs : NCBIFRRS1 [Mapview hg19]  FRRS1 [Mapview hg38]
OMIM611578   
Gene and transcription
Genbank (Entrez)AK131302 BC029438 BC156175 BC157016
RefSeq transcript (Entrez)NM_001013660
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FRRS1
Cluster EST : UnigeneHs.454779 [ NCBI ]
CGAP (NCI)Hs.454779
Alternative Splicing GalleryENSG00000156869
Gene ExpressionFRRS1 [ NCBI-GEO ]   FRRS1 [ EBI - ARRAY_EXPRESS ]   FRRS1 [ SEEK ]   FRRS1 [ MEM ]
Gene Expression Viewer (FireBrowse)FRRS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)391059
GTEX Portal (Tissue expression)FRRS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNA5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNA5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNA5
Splice isoforms : SwissVarQ6ZNA5
Catalytic activity : Enzyme1.-.-.- [ Enzyme-Expasy ]   1.-.-.-1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   
PhosPhoSitePlusQ6ZNA5
Domaine pattern : Prosite (Expaxy)CYTOCHROME_B561 (PS50939)    DOMON (PS50836)    REELIN (PS51019)   
Domains : Interpro (EBI)Cyt_b561/ferric_Rdtase_TM    DOMON_domain    Reeler_dom   
Domain families : Pfam (Sanger)DOMON (PF03351)    Reeler (PF02014)   
Domain families : Pfam (NCBI)pfam03351    pfam02014   
Domain families : Smart (EMBL)B561 (SM00665)  DoH (SM00664)  
Conserved Domain (NCBI)FRRS1
DMDM Disease mutations391059
Blocks (Seattle)FRRS1
SuperfamilyQ6ZNA5
Human Protein AtlasENSG00000156869
Peptide AtlasQ6ZNA5
HPRD18403
IPIIPI00418594   IPI00878384   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNA5
IntAct (EBI)Q6ZNA5
FunCoupENSG00000156869
BioGRIDFRRS1
STRING (EMBL)FRRS1
ZODIACFRRS1
Ontologies - Pathways
QuickGOQ6ZNA5
Ontology : AmiGOferric-chelate reductase activity  integral component of membrane  metal ion binding  oxidation-reduction process  
Ontology : EGO-EBIferric-chelate reductase activity  integral component of membrane  metal ion binding  oxidation-reduction process  
NDEx NetworkFRRS1
Atlas of Cancer Signalling NetworkFRRS1
Wikipedia pathwaysFRRS1
Orthology - Evolution
OrthoDB391059
GeneTree (enSembl)ENSG00000156869
Phylogenetic Trees/Animal Genes : TreeFamFRRS1
HOVERGENQ6ZNA5
HOGENOMQ6ZNA5
Homologs : HomoloGeneFRRS1
Homology/Alignments : Family Browser (UCSC)FRRS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFRRS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FRRS1
dbVarFRRS1
ClinVarFRRS1
1000_GenomesFRRS1 
Exome Variant ServerFRRS1
ExAC (Exome Aggregation Consortium)FRRS1 (select the gene name)
Genetic variants : HAPMAP391059
Genomic Variants (DGV)FRRS1 [DGVbeta]
DECIPHERFRRS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFRRS1 
Mutations
ICGC Data PortalFRRS1 
TCGA Data PortalFRRS1 
Broad Tumor PortalFRRS1
OASIS PortalFRRS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFRRS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFRRS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FRRS1
DgiDB (Drug Gene Interaction Database)FRRS1
DoCM (Curated mutations)FRRS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FRRS1 (select a term)
intoGenFRRS1
Cancer3DFRRS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611578   
Orphanet
MedgenFRRS1
Genetic Testing Registry FRRS1
NextProtQ6ZNA5 [Medical]
TSGene391059
GENETestsFRRS1
Target ValidationFRRS1
Huge Navigator FRRS1 [HugePedia]
snp3D : Map Gene to Disease391059
BioCentury BCIQFRRS1
ClinGenFRRS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD391059
Chemical/Pharm GKB GenePA142670941
Clinical trialFRRS1
Miscellaneous
canSAR (ICR)FRRS1 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFRRS1
EVEXFRRS1
GoPubMedFRRS1
iHOPFRRS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:08:58 CEST 2017

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