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FRS3 (fibroblast growth factor receptor substrate 3)

Identity

Other namesFRS2B
FRS2beta
SNT-2
SNT2
HGNC (Hugo) FRS3
LocusID (NCBI) 10817
Location 6p21.1
Location_base_pair Starts at 41737914 and ends at 41747630 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)FRS3   16970
Entrez_Gene (NCBI)FRS3  10817  fibroblast growth factor receptor substrate 3
Cards
GeneCards (Weizmann)FRS3
Ensembl (Hinxton)ENSG00000137218 [Gene_View]  chr6:41737914-41747630 [Contig_View]  FRS3 [Vega]
AceView (NCBI)FRS3
Genatlas (Paris)FRS3
SOURCE (Stanford)NM_006653
Genomic and cartography
GoldenPath (UCSC)FRS3  -  6p21.1   chr6:41737914-41747630 -  6p21.1   [Description]    (hg19-Feb_2009)
EnsemblFRS3 - 6p21.1 [CytoView]
Mapping of homologs : NCBIFRS3 [Mapview]
OMIM607744   
Gene and transcription
Genbank (Entrez)AF036718 BC010611 BM741175 CR457026 DQ892075
RefSeq transcript (SRS)NM_006653
RefSeq transcript (Entrez)NM_006653
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NT_007592 NW_001838981 NW_004078026
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_007592 NW_001838981 NW_004078026
Consensus coding sequences : CCDS (NCBI)FRS3
Cluster EST : UnigeneHs.194208 [ SRS ] Hs.194208 [ NCBI ]
CGAP (NCI)Hs.194208
Alternative Splicing : Fast-db (Paris)GSHG0026606
Alternative Splicing GalleryENSG00000137218
Gene ExpressionFRS3 [ NCBI-GEO ]   FRS3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43559 (SRS) O43559 (Uniprot)
NextProtO43559
With graphics : InterProO43559
Splice isoforms : SwissVarO43559(Swissvar)
Domaine pattern : Prosite (SRS)IRS_PTB (PS51064)   
Domaine pattern : Prosite (Expaxy)IRS_PTB (PS51064)   
Domains : Interpro (SRS)Insln_rcpt_S1    PH_like_dom   
Domains : Interpro (EBI)Insln_rcpt_S1    PH_like_dom   
Related proteins : CluSTrO43559
Domain families : Pfam (SRS)IRS (PF02174)   
Domain families : Pfam (Sanger)IRS (PF02174)   
Domain families : Pfam (NCBI)pfam02174   
Domain families : Smart (EMBL)PTBI (SM00310)  
DMDM10817
Blocks (Seattle)O43559
PDB (SRS)2KUP    2KUQ    2YS5    2YT2   
PDB (PDBSum)2KUP    2KUQ    2YS5    2YT2   
PDB (IMB)2KUP    2KUQ    2YS5    2YT2   
PDB (RSDB)2KUP    2KUQ    2YS5    2YT2   
Human Protein AtlasENSG00000137218
HPRD06373
IPIIPI00009089   IPI00644089   IPI00852866   
Protein Interaction databases
DIP (DOE-UCLA)O43559
IntAct (EBI)O43559
FunCoupENSG00000137218
REACTOMEFRS3
Protein Interaction Database10817
BioGRIDFRS3
InParanoidO43559
Interologous Interaction database O43559
IntegromeDBFRS3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FRS3
SNP (GeneSNP Utah)FRS3
SNP : HGBaseFRS3
Genetic variants : HAPMAPFRS3
Somatic Mutations in Cancer : COSMICFRS3 
CONAN: Copy Number AnalysisFRS3 
Mutations and Diseases : HGMDFRS3
OMIM607744   
GENETests607744   
Disease Genetic AssociationFRS3
Huge Navigator FRS3 [HugePedia]  FRS3 [HugeCancerGEM]
Genomic VariantsFRS3  FRS3 [DGVbeta]
snp3D : Map Gene to Disease10817
General knowledge
Homologs : HomoloGeneFRS3
Homology/Alignments : Family Browser (UCSC)FRS3
Phylogenetic Trees/Animal Genes : TreeFamFRS3
Chemical/Protein Interactions : CTD10817
Chemical/Pharm GKB GenePA134961503
Clinical trialFRS3
Cancer Resource (Charite)ENSG00000137218
Ontology : AmiGOfibroblast growth factor receptor binding  insulin receptor binding  plasma membrane  signal transduction  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  
Ontology : EGO-EBIfibroblast growth factor receptor binding  insulin receptor binding  plasma membrane  signal transduction  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
PubGeneFRS3
iHOPFRS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:37:14 CEST 2013
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