FSD1 (fibronectin type III and SPRY domain containing 1)

2008-03-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
GLFND,MIR1
FUSION GENES

Other Information

Locus ID:

NCBI: 79187
MIM: 609828
HGNC: 13745
Ensembl: ENSG00000105255

Variants:

dbSNP: 79187
ClinVar: 79187
TCGA: ENSG00000105255
COSMIC: FSD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105255ENST00000221856Q9BTV5
ENSG00000105255ENST00000594438M0QY68
ENSG00000105255ENST00000597480M0R2F6
ENSG00000105255ENST00000597590M0R366
ENSG00000105255ENST00000601006M0R1R0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
260366332015MiR-1 downregulation correlates with poor survival in clear cell renal cell carcinoma where it interferes with cell cycle regulation and metastasis.23
284714482017MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis.22
279237122017Regulation of microRNA-1 (miR-1) expression in human cancer.16
121540702002A novel centrosome-associated protein with affinity for microtubules.4
305513912019MiR-1 inhibits prostate cancer PC3 cells proliferation through the Akt/mTOR signaling pathway by binding to c-Met.3
305382482018Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.2

Citation

Dessen P

FSD1 (fibronectin type III and SPRY domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-03-01

Online version: http://atlasgeneticsoncology.org/gene/50055/fsd1