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FSTL4 (follistatin like 4)

Identity

Alias_namesfollistatin-like 4
Alias_symbol (synonym)KIAA1061
Other alias-
HGNC (Hugo) FSTL4
LocusID (NCBI) 23105
Atlas_Id 63613
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 133196460 and ends at 133612532 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AFF4 (5q31.1) / FSTL4 (5q31.1)FSTL4 (5q31.1) / SLIT3 (5q34)TWF2 (3p21.2) / FSTL4 (5q31.1)
TWF2 FSTL4AFF4 FSTL4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FSTL4   21389
Cards
Entrez_Gene (NCBI)FSTL4  23105  follistatin like 4
Aliases
GeneCards (Weizmann)FSTL4
Ensembl hg19 (Hinxton)ENSG00000053108 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000053108 [Gene_View]  chr5:133196460-133612532 [Contig_View]  FSTL4 [Vega]
ICGC DataPortalENSG00000053108
TCGA cBioPortalFSTL4
AceView (NCBI)FSTL4
Genatlas (Paris)FSTL4
WikiGenes23105
SOURCE (Princeton)FSTL4
Genetics Home Reference (NIH)FSTL4
Genomic and cartography
GoldenPath hg38 (UCSC)FSTL4  -     chr5:133196460-133612532 -  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FSTL4  -     5q31.1   [Description]    (hg19-Feb_2009)
EnsemblFSTL4 - 5q31.1 [CytoView hg19]  FSTL4 - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBIFSTL4 [Mapview hg19]  FSTL4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB028984 AK026109 AK055684 AK056284 BC024300
RefSeq transcript (Entrez)NM_015082
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FSTL4
Cluster EST : UnigeneHs.483390 [ NCBI ]
CGAP (NCI)Hs.483390
Alternative Splicing GalleryENSG00000053108
Gene ExpressionFSTL4 [ NCBI-GEO ]   FSTL4 [ EBI - ARRAY_EXPRESS ]   FSTL4 [ SEEK ]   FSTL4 [ MEM ]
Gene Expression Viewer (FireBrowse)FSTL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23105
GTEX Portal (Tissue expression)FSTL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6MZW2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6MZW2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6MZW2
Splice isoforms : SwissVarQ6MZW2
PhosPhoSitePlusQ6MZW2
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    IG_LIKE (PS50835)    KAZAL_2 (PS51465)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Kazal_dom    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)   
Domain families : Pfam (NCBI)pfam07648   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  KAZAL (SM00280)  
Conserved Domain (NCBI)FSTL4
DMDM Disease mutations23105
Blocks (Seattle)FSTL4
SuperfamilyQ6MZW2
Human Protein AtlasENSG00000053108
Peptide AtlasQ6MZW2
HPRD17022
IPIIPI00477747   IPI00298956   IPI00787330   IPI00903294   IPI00966154   
Protein Interaction databases
DIP (DOE-UCLA)Q6MZW2
IntAct (EBI)Q6MZW2
FunCoupENSG00000053108
BioGRIDFSTL4
STRING (EMBL)FSTL4
ZODIACFSTL4
Ontologies - Pathways
QuickGOQ6MZW2
Ontology : AmiGOcalcium ion binding  extracellular region  secretory granule  negative regulation of brain-derived neurotrophic factor receptor signaling pathway  brain-derived neurotrophic factor binding  negative regulation of collateral sprouting  negative regulation of dendritic spine development  
Ontology : EGO-EBIcalcium ion binding  extracellular region  secretory granule  negative regulation of brain-derived neurotrophic factor receptor signaling pathway  brain-derived neurotrophic factor binding  negative regulation of collateral sprouting  negative regulation of dendritic spine development  
NDEx NetworkFSTL4
Atlas of Cancer Signalling NetworkFSTL4
Wikipedia pathwaysFSTL4
Orthology - Evolution
OrthoDB23105
GeneTree (enSembl)ENSG00000053108
Phylogenetic Trees/Animal Genes : TreeFamFSTL4
HOVERGENQ6MZW2
HOGENOMQ6MZW2
Homologs : HomoloGeneFSTL4
Homology/Alignments : Family Browser (UCSC)FSTL4
Gene fusions - Rearrangements
Fusion: TCGATWF2 FSTL4
Fusion: TCGAAFF4 FSTL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFSTL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FSTL4
dbVarFSTL4
ClinVarFSTL4
1000_GenomesFSTL4 
Exome Variant ServerFSTL4
ExAC (Exome Aggregation Consortium)FSTL4 (select the gene name)
Genetic variants : HAPMAP23105
Genomic Variants (DGV)FSTL4 [DGVbeta]
DECIPHERFSTL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFSTL4 
Mutations
ICGC Data PortalFSTL4 
TCGA Data PortalFSTL4 
Broad Tumor PortalFSTL4
OASIS PortalFSTL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFSTL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFSTL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FSTL4
DgiDB (Drug Gene Interaction Database)FSTL4
DoCM (Curated mutations)FSTL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FSTL4 (select a term)
intoGenFSTL4
Cancer3DFSTL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenFSTL4
Genetic Testing Registry FSTL4
NextProtQ6MZW2 [Medical]
TSGene23105
GENETestsFSTL4
Target ValidationFSTL4
Huge Navigator FSTL4 [HugePedia]
snp3D : Map Gene to Disease23105
BioCentury BCIQFSTL4
ClinGenFSTL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23105
Chemical/Pharm GKB GenePA134969998
Clinical trialFSTL4
Miscellaneous
canSAR (ICR)FSTL4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFSTL4
EVEXFSTL4
GoPubMedFSTL4
iHOPFSTL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:49:59 CEST 2017

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