Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FUCA2 (fucosidase, alpha-L- 2, plasma)

Identity

Alias_symbol (synonym)MGC1314
dJ20N2.5
Other alias
HGNC (Hugo) FUCA2
LocusID (NCBI) 2519
Atlas_Id 63626
Location 6q24.2  [Link to chromosome band 6q24]
Location_base_pair Starts at 143494812 and ends at 143511883 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FUCA2 (6q24.2) / SSR2 (1q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FUCA2   4008
Cards
Entrez_Gene (NCBI)FUCA2  2519  fucosidase, alpha-L- 2, plasma
AliasesdJ20N2.5
GeneCards (Weizmann)FUCA2
Ensembl hg19 (Hinxton)ENSG00000001036 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000001036 [Gene_View]  ENSG00000001036 [Sequence]  chr6:143494812-143511883 [Contig_View]  FUCA2 [Vega]
ICGC DataPortalENSG00000001036
TCGA cBioPortalFUCA2
AceView (NCBI)FUCA2
Genatlas (Paris)FUCA2
WikiGenes2519
SOURCE (Princeton)FUCA2
Genetics Home Reference (NIH)FUCA2
Genomic and cartography
GoldenPath hg38 (UCSC)FUCA2  -     chr6:143494812-143511883 -  6q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FUCA2  -     6q24.2   [Description]    (hg19-Feb_2009)
EnsemblFUCA2 - 6q24.2 [CytoView hg19]  FUCA2 - 6q24.2 [CytoView hg38]
Mapping of homologs : NCBIFUCA2 [Mapview hg19]  FUCA2 [Mapview hg38]
OMIM136820   
Gene and transcription
Genbank (Entrez)AK075458 AK296485 AK315475 AY358551 BC003060
RefSeq transcript (Entrez)NM_032020
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FUCA2
Cluster EST : UnigeneHs.17680 [ NCBI ]
CGAP (NCI)Hs.17680
Alternative Splicing GalleryENSG00000001036
Gene ExpressionFUCA2 [ NCBI-GEO ]   FUCA2 [ EBI - ARRAY_EXPRESS ]   FUCA2 [ SEEK ]   FUCA2 [ MEM ]
Gene Expression Viewer (FireBrowse)FUCA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2519
GTEX Portal (Tissue expression)FUCA2
Human Protein AtlasENSG00000001036-FUCA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BTY2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BTY2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BTY2
Splice isoforms : SwissVarQ9BTY2
Catalytic activity : Enzyme3.2.1.51 [ Enzyme-Expasy ]   3.2.1.513.2.1.51 [ IntEnz-EBI ]   3.2.1.51 [ BRENDA ]   3.2.1.51 [ KEGG ]   
PhosPhoSitePlusQ9BTY2
Domaine pattern : Prosite (Expaxy)ALPHA_L_FUCOSIDASE (PS00385)   
Domains : Interpro (EBI)FUC_metazoa-typ    Fucosidase_C    Glyco_hydro_29    Glyco_hydro_29_CS    Glyco_hydro_b    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Alpha_L_fucos (PF01120)    Fucosidase_C (PF16757)   
Domain families : Pfam (NCBI)pfam01120    pfam16757   
Domain families : Smart (EMBL)Alpha_L_fucos (SM00812)  
Conserved Domain (NCBI)FUCA2
DMDM Disease mutations2519
Blocks (Seattle)FUCA2
SuperfamilyQ9BTY2
Human Protein Atlas [tissue]ENSG00000001036-FUCA2 [tissue]
Peptide AtlasQ9BTY2
HPRD00649
IPIIPI00012440   IPI00385460   IPI00385461   
Protein Interaction databases
DIP (DOE-UCLA)Q9BTY2
IntAct (EBI)Q9BTY2
FunCoupENSG00000001036
BioGRIDFUCA2
STRING (EMBL)FUCA2
ZODIACFUCA2
Ontologies - Pathways
QuickGOQ9BTY2
Ontology : AmiGO###############################################################################################################################################################################################################################################################                      
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                      
Pathways : KEGGN-Glycan degradation    Glycan structures - degradation   
NDEx NetworkFUCA2
Atlas of Cancer Signalling NetworkFUCA2
Wikipedia pathwaysFUCA2
Orthology - Evolution
OrthoDB2519
GeneTree (enSembl)ENSG00000001036
Phylogenetic Trees/Animal Genes : TreeFamFUCA2
HOVERGENQ9BTY2
HOGENOMQ9BTY2
Homologs : HomoloGeneFUCA2
Homology/Alignments : Family Browser (UCSC)FUCA2
Gene fusions - Rearrangements
Fusion : QuiverFUCA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFUCA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FUCA2
dbVarFUCA2
ClinVarFUCA2
1000_GenomesFUCA2 
Exome Variant ServerFUCA2
ExAC (Exome Aggregation Consortium)ENSG00000001036
GNOMAD BrowserENSG00000001036
Varsome BrowserFUCA2
Genetic variants : HAPMAP2519
Genomic Variants (DGV)FUCA2 [DGVbeta]
DECIPHERFUCA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFUCA2 
Mutations
ICGC Data PortalFUCA2 
TCGA Data PortalFUCA2 
Broad Tumor PortalFUCA2
OASIS PortalFUCA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFUCA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFUCA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FUCA2
DgiDB (Drug Gene Interaction Database)FUCA2
DoCM (Curated mutations)FUCA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FUCA2 (select a term)
intoGenFUCA2
Cancer3DFUCA2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM136820   
Orphanet
DisGeNETFUCA2
MedgenFUCA2
Genetic Testing Registry FUCA2
NextProtQ9BTY2 [Medical]
TSGene2519
GENETestsFUCA2
Target ValidationFUCA2
Huge Navigator FUCA2 [HugePedia]
snp3D : Map Gene to Disease2519
BioCentury BCIQFUCA2
ClinGenFUCA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2519
Chemical/Pharm GKB GenePA28424
Clinical trialFUCA2
Miscellaneous
canSAR (ICR)FUCA2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFUCA2
EVEXFUCA2
GoPubMedFUCA2
iHOPFUCA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 13:46:46 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.