FUT1 (fucosyltransferase 1 (H blood group))

2007-04-01  

Identity

HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
H,HH,HSC

Other Information

Locus ID:

NCBI: 2523
MIM: 211100
HGNC: 4012
Ensembl: ENSG00000174951

Variants:

dbSNP: 2523
ClinVar: 2523
TCGA: ENSG00000174951
COSMIC: FUT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174951ENST00000310160P19526
ENSG00000174951ENST00000310160Q6IZA2
ENSG00000174951ENST00000645652P19526
ENSG00000174951ENST00000645652Q6IZA2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGko00601
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGhsa00601
Glycosphingolipid biosynthesis - globo and isoglobo seriesKEGGhsa00603
Metabolic pathwaysKEGGhsa01100

References

Pubmed IDYearTitleCitations
126979022003Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways.132
180232902008Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth.21
182051782008Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis.14
275607162016Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells.12
174590612007Changes in the invasive and metastatic capacities of HT-29/M3 cells induced by the expression of fucosyltransferase 1.11
191378142008[alpha1,2-fucosyltransferase gene transfection influences on biological behavior of ovarian carcinoma-derived RMG-I cells].11
245933062014Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells.11
294880532018miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis.11
220530552012Macrophages regulate expression of α1,2-fucosyltransferase genes in human endometrial epithelial cells.10
289408952017miR-339-5p downregulation contributes to Taxol resistance in small-cell lung cancer by targeting α1,2-fucosyltransferase 1.10

Citation

Dessen P

FUT1 (fucosyltransferase 1 (H blood group))

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46808/fut1