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FUT10 (fucosyltransferase 10)

Identity

Alias (NCBI)FUCTX
HGNC (Hugo) FUT10
HGNC Alias namealpha (1,3) fucosyltransferase
HGNC Previous namefucosyltransferase 10 (alpha (1,3) fucosyltransferase)
LocusID (NCBI) 84750
Atlas_Id 63629
Location 8p12  [Link to chromosome band 8p12]
Location_base_pair Starts at 33370826 and ends at 33473146 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANK1 (8p11.21) / FUT10 (8p12)DNAH12 (3p14.3) / FUT10 (8p12)FUT10 (8p12) / GAB2 (11q14.1)
FUT10 (8p12) / TDRP (8p23.3)LIPA (10q23.31) / FUT10 (8p12)FUT10 GAB2
FUT10 C8orf42

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(8;8)(p11;p12) ANK1/FUT10
t(8;8)(p12;p23) FUT10/TDRP
t(8;11)(p12;q14) FUT10/GAB2

External links

Nomenclature
HGNC (Hugo)FUT10   19234
Cards
Entrez_Gene (NCBI)FUT10    fucosyltransferase 10
AliasesFUCTX
GeneCards (Weizmann)FUT10
Ensembl hg19 (Hinxton)ENSG00000172728 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172728 [Gene_View]  ENSG00000172728 [Sequence]  chr8:33370826-33473146 [Contig_View]  FUT10 [Vega]
ICGC DataPortalENSG00000172728
TCGA cBioPortalFUT10
AceView (NCBI)FUT10
Genatlas (Paris)FUT10
SOURCE (Princeton)FUT10
Genetics Home Reference (NIH)FUT10
Genomic and cartography
GoldenPath hg38 (UCSC)FUT10  -     chr8:33370826-33473146 -  8p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FUT10  -     8p12   [Description]    (hg19-Feb_2009)
GoldenPathFUT10 - 8p12 [CytoView hg19]  FUT10 - 8p12 [CytoView hg38]
ImmunoBaseENSG00000172728
genome Data Viewer NCBIFUT10 [Mapview hg19]  
OMIM616931   
Gene and transcription
Genbank (Entrez)AJ431184 AJ512465 AJ535838 AJ535839 AJ582015
RefSeq transcript (Entrez)NM_032664
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FUT10
Alternative Splicing GalleryENSG00000172728
Gene ExpressionFUT10 [ NCBI-GEO ]   FUT10 [ EBI - ARRAY_EXPRESS ]   FUT10 [ SEEK ]   FUT10 [ MEM ]
Gene Expression Viewer (FireBrowse)FUT10 [ Firebrowse - Broad ]
GenevisibleExpression of FUT10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84750
GTEX Portal (Tissue expression)FUT10
Human Protein AtlasENSG00000172728-FUT10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P4F1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P4F1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P4F1
Splice isoforms : SwissVarQ6P4F1
Catalytic activity : Enzyme2.4.1.- [ Enzyme-Expasy ]   2.4.1.-2.4.1.- [ IntEnz-EBI ]   2.4.1.- [ BRENDA ]   2.4.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ6P4F1
Domains : Interpro (EBI)Alpha-1_3-FUT_met    Glyco_tran_10_N    Glyco_trans_10    GT10-like_sf   
Domain families : Pfam (Sanger)Glyco_tran_10_N (PF17039)    Glyco_transf_10 (PF00852)   
Domain families : Pfam (NCBI)pfam17039    pfam00852   
Conserved Domain (NCBI)FUT10
Blocks (Seattle)FUT10
SuperfamilyQ6P4F1
Human Protein Atlas [tissue]ENSG00000172728-FUT10 [tissue]
Peptide AtlasQ6P4F1
IPIIPI00152615   IPI00217027   IPI00855877   IPI00855896   IPI00855757   IPI00746897   IPI00440692   IPI00911112   
Protein Interaction databases
DIP (DOE-UCLA)Q6P4F1
IntAct (EBI)Q6P4F1
BioGRIDFUT10
STRING (EMBL)FUT10
ZODIACFUT10
Ontologies - Pathways
QuickGOQ6P4F1
Ontology : AmiGOnucleoplasm  endoplasmic reticulum  Golgi apparatus  Golgi apparatus  protein folding  protein glycosylation  protein glycosylation  protein targeting  nervous system development  fertilization  integral component of membrane  cerebral cortex radially oriented cell migration  hemopoiesis  Golgi cisterna membrane  fucosylation  wound healing  L-fucose catabolic process  alpha-(1->3)-fucosyltransferase activity  alpha-(1->3)-fucosyltransferase activity  neuronal stem cell population maintenance  
Ontology : EGO-EBInucleoplasm  endoplasmic reticulum  Golgi apparatus  Golgi apparatus  protein folding  protein glycosylation  protein glycosylation  protein targeting  nervous system development  fertilization  integral component of membrane  cerebral cortex radially oriented cell migration  hemopoiesis  Golgi cisterna membrane  fucosylation  wound healing  L-fucose catabolic process  alpha-(1->3)-fucosyltransferase activity  alpha-(1->3)-fucosyltransferase activity  neuronal stem cell population maintenance  
NDEx NetworkFUT10
Atlas of Cancer Signalling NetworkFUT10
Wikipedia pathwaysFUT10
Orthology - Evolution
OrthoDB84750
GeneTree (enSembl)ENSG00000172728
Phylogenetic Trees/Animal Genes : TreeFamFUT10
HOGENOMQ6P4F1
Homologs : HomoloGeneFUT10
Homology/Alignments : Family Browser (UCSC)FUT10
Gene fusions - Rearrangements
Fusion PortalFUT10 GAB2
Fusion PortalFUT10 C8orf42
Fusion : QuiverFUT10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFUT10 [hg38]
dbVarFUT10
ClinVarFUT10
MonarchFUT10
1000_GenomesFUT10 
Exome Variant ServerFUT10
GNOMAD BrowserENSG00000172728
Varsome BrowserFUT10
Genomic Variants (DGV)FUT10 [DGVbeta]
DECIPHERFUT10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFUT10 
Mutations
ICGC Data PortalFUT10 
TCGA Data PortalFUT10 
Broad Tumor PortalFUT10
OASIS PortalFUT10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFUT10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFUT10
Mutations and Diseases : HGMDFUT10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FUT10
DgiDB (Drug Gene Interaction Database)FUT10
DoCM (Curated mutations)FUT10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FUT10 (select a term)
intoGenFUT10
Cancer3DFUT10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616931   
Orphanet
DisGeNETFUT10
MedgenFUT10
Genetic Testing Registry FUT10
NextProtQ6P4F1 [Medical]
GENETestsFUT10
Target ValidationFUT10
Huge Navigator FUT10 [HugePedia]
ClinGenFUT10
Clinical trials, drugs, therapy
MyCancerGenomeFUT10
Protein Interactions : CTD
Pharm GKB GenePA134872572
Clinical trialFUT10
Miscellaneous
canSAR (ICR)FUT10 (select the gene name)
HarmonizomeFUT10
DataMed IndexFUT10
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFUT10
EVEXFUT10
GoPubMedFUT10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:55:06 CET 2020
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