Identity
HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
B12QTL1,SE,SEC2,Se2,sej
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2524
MIM: 182100
HGNC: 4013
Ensembl: ENSG00000176920
Variants:
dbSNP: 2524
ClinVar: 2524
TCGA: ENSG00000176920
COSMIC: FUT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 32451486 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 32451486 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36678342 | 2023 | Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants. | 10 |
| 36719978 | 2023 | Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media. | 0 |
| 36734282 | 2023 | FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β‑catenin pathway. | 3 |
| 37342060 | 2023 | Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype. | 0 |
| 37504220 | 2023 | Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes. | 3 |
| 36678342 | 2023 | Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants. | 10 |
| 36719978 | 2023 | Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media. | 0 |
| 36734282 | 2023 | FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β‑catenin pathway. | 3 |
| 37342060 | 2023 | Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype. | 0 |
| 37504220 | 2023 | Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes. | 3 |
| 34739405 | 2022 | Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease. | 0 |
| 36263525 | 2022 | Effect of the variant rs602662 of FUT2 gene on anthropometric and metabolic parameters in a Caucasian obese population. | 0 |
| 36335265 | 2022 | Maternal and child FUT2 and FUT3 status demonstrate relationship with gut health, body composition and growth of children in Bangladesh. | 0 |
| 36552800 | 2022 | FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells. | 3 |
| 34739405 | 2022 | Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease. | 0 |
Citation
Dessen P
FUT2 (fucosyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45946/fut2
