FUT7 (fucosyltransferase 7)

2010-10-01  

Identity

HGNC
FUT7
LOCATION
9q34.3
LOCUSID
2529
ALIAS
FucT-VII

Other Information

Locus ID:

NCBI: 2529
MIM: 602030
HGNC: 4018
Ensembl: ENSG00000180549

Variants:

dbSNP: 2529
ClinVar: 2529
TCGA: ENSG00000180549
COSMIC: FUT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180549ENST00000314412Q11130

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGko00601
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGhsa00601
Metabolic pathwaysKEGGhsa01100

References

Pubmed IDYearTitleCitations
155794662005Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VII.26
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
125060412003Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element.10
174360812007Alpha1,3 Fucosyltransferase-VII modifies the susceptibility of apoptosis induced by ultraviolet and retinoic acid in human hepatocarcinoma cells.6
184029462009Overexpression of fucosyltransferase VII (FUT7) promotes embryo adhesion and implantation.6
152629952004H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells.5
172291542007Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway.5
184521572008alpha1,3 fucosyltransferase-VII up-regulates the mRNA of alpha5 integrin and its biological function.5
154649882004Highly sensitive cell-based assay system to monitor the sialyl Lewis X biosynthesis mediated by alpha1-3 fucosyltransferase-VII.4
211975612011sLeX/L-selectin mediates adhesion in vitro implantation model.4

Citation

Dessen P

FUT7 (fucosyltransferase 7)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51731/fut7