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FYCO1 (FYVE and coiled-coil domain autophagy adaptor 1)

Identity

Alias (NCBI)CATC2
CTRCT18
RUFY3
ZFYVE7
HGNC (Hugo) FYCO1
HGNC Alias symbFLJ13335
ZFYVE7
HGNC Previous nameFYVE and coiled-coil domain containing 1
LocusID (NCBI) 79443
Atlas_Id 43868
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 45917903 and ends at 45995824 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FYCO1 (3p21.31) / ATG7 (3p25.3)FYCO1 (3p21.31) / FKBP15 (9q32)FYCO1 (3p21.31) / FYCO1 (3p21.31)
FYCO1 (3p21.31) / HRAS (11p15.5)FYCO1 (3p21.31) / RAF1 (3p25.2)FYCO1 (3p21.31) / SAT1 (Xp22.11)
FYCO1 (3p21.31) / TLN1 (9p13.3)PDCD11 (10q24.33) / FYCO1 (3p21.31)PPME1 (11q13.4) / FYCO1 (3p21.31)
FYCO1 3p21.31 / ATG7 3p25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FYCO1   14673
Cards
Entrez_Gene (NCBI)FYCO1    FYVE and coiled-coil domain autophagy adaptor 1
AliasesCATC2; CTRCT18; RUFY3; ZFYVE7
GeneCards (Weizmann)FYCO1
Ensembl hg19 (Hinxton)ENSG00000163820 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163820 [Gene_View]  ENSG00000163820 [Sequence]  chr3:45917903-45995824 [Contig_View]  FYCO1 [Vega]
ICGC DataPortalENSG00000163820
TCGA cBioPortalFYCO1
AceView (NCBI)FYCO1
Genatlas (Paris)FYCO1
SOURCE (Princeton)FYCO1
Genetics Home Reference (NIH)FYCO1
Genomic and cartography
GoldenPath hg38 (UCSC)FYCO1  -     chr3:45917903-45995824 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FYCO1  -     3p21.31   [Description]    (hg19-Feb_2009)
GoldenPathFYCO1 - 3p21.31 [CytoView hg19]  FYCO1 - 3p21.31 [CytoView hg38]
ImmunoBaseENSG00000163820
Genome Data Viewer NCBIFYCO1 [Mapview hg19]  
OMIM607182   610019   
Gene and transcription
Genbank (Entrez)AA628466 AJ292348 AK023397 AK074165 AL832358
RefSeq transcript (Entrez)NM_001386421 NM_001386422 NM_001386423 NM_001386424 NM_001386425 NM_001386426 NM_001386427 NM_001386428 NM_001386429 NM_001386430 NM_024513
Consensus coding sequences : CCDS (NCBI)FYCO1
Gene ExpressionFYCO1 [ NCBI-GEO ]   FYCO1 [ EBI - ARRAY_EXPRESS ]   FYCO1 [ SEEK ]   FYCO1 [ MEM ]
Gene Expression Viewer (FireBrowse)FYCO1 [ Firebrowse - Broad ]
GenevisibleExpression of FYCO1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79443
GTEX Portal (Tissue expression)FYCO1
Human Protein AtlasENSG00000163820-FYCO1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQS8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQS8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQS8
PhosPhoSitePlusQ9BQS8
Domaine pattern : Prosite (Expaxy)GOLD (PS50866)    RUN (PS50826)    ZF_FYVE (PS50178)   
Domains : Interpro (EBI)FYCO1    GOLD_dom    GOLD_dom_sf    Run_dom    Run_dom_sf    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)    RUN (PF02759)   
Domain families : Pfam (NCBI)pfam01363    pfam02759   
Domain families : Smart (EMBL)FYVE (SM00064)  
Conserved Domain (NCBI)FYCO1
PDB (RSDB)5CX3    5D94    7BQI   
PDB Europe5CX3    5D94    7BQI   
PDB (PDBSum)5CX3    5D94    7BQI   
PDB (IMB)5CX3    5D94    7BQI   
Structural Biology KnowledgeBase5CX3    5D94    7BQI   
SCOP (Structural Classification of Proteins)5CX3    5D94    7BQI   
CATH (Classification of proteins structures)5CX3    5D94    7BQI   
SuperfamilyQ9BQS8
AlphaFold pdb e-kbQ9BQS8   
Human Protein Atlas [tissue]ENSG00000163820-FYCO1 [tissue]
HPRD06215
Protein Interaction databases
DIP (DOE-UCLA)Q9BQS8
IntAct (EBI)Q9BQS8
BioGRIDFYCO1
STRING (EMBL)FYCO1
ZODIACFYCO1
Ontologies - Pathways
QuickGOQ9BQS8
Ontology : AmiGOprotein binding  lysosome  lysosome  late endosome  late endosome  autophagosome  autophagosome  Golgi apparatus  membrane  intracellular membrane-bounded organelle  metal ion binding  plus-end-directed vesicle transport along microtubule  plus-end-directed vesicle transport along microtubule  positive regulation of autophagosome maturation  positive regulation of autophagosome maturation  
Ontology : EGO-EBIprotein binding  lysosome  lysosome  late endosome  late endosome  autophagosome  autophagosome  Golgi apparatus  membrane  intracellular membrane-bounded organelle  metal ion binding  plus-end-directed vesicle transport along microtubule  plus-end-directed vesicle transport along microtubule  positive regulation of autophagosome maturation  positive regulation of autophagosome maturation  
NDEx NetworkFYCO1
Atlas of Cancer Signalling NetworkFYCO1
Wikipedia pathwaysFYCO1
Orthology - Evolution
OrthoDB79443
GeneTree (enSembl)ENSG00000163820
Phylogenetic Trees/Animal Genes : TreeFamFYCO1
Homologs : HomoloGeneFYCO1
Homology/Alignments : Family Browser (UCSC)FYCO1
Gene fusions - Rearrangements
Fusion : MitelmanFYCO1/ATG7 [3p21.31/3p25.3]  
Fusion : MitelmanFYCO1/RAF1 [3p21.31/3p25.2]  
Fusion : QuiverFYCO1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFYCO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FYCO1
dbVarFYCO1
ClinVarFYCO1
MonarchFYCO1
1000_GenomesFYCO1 
Exome Variant ServerFYCO1
GNOMAD BrowserENSG00000163820
Varsome BrowserFYCO1
ACMGFYCO1 variants
VarityQ9BQS8
Genomic Variants (DGV)FYCO1 [DGVbeta]
DECIPHERFYCO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFYCO1 
Mutations
ICGC Data PortalFYCO1 
TCGA Data PortalFYCO1 
Broad Tumor PortalFYCO1
OASIS PortalFYCO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFYCO1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFYCO1
Mutations and Diseases : HGMDFYCO1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFYCO1
DgiDB (Drug Gene Interaction Database)FYCO1
DoCM (Curated mutations)FYCO1
CIViC (Clinical Interpretations of Variants in Cancer)FYCO1
Cancer3DFYCO1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607182    610019   
Orphanet14008    14011   
DisGeNETFYCO1
MedgenFYCO1
Genetic Testing Registry FYCO1
NextProtQ9BQS8 [Medical]
GENETestsFYCO1
Target ValidationFYCO1
Huge Navigator FYCO1 [HugePedia]
ClinGenFYCO1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeFYCO1
Protein Interactions : CTDFYCO1
Pharm GKB GenePA28453
PharosQ9BQS8
Clinical trialFYCO1
Miscellaneous
canSAR (ICR)FYCO1
HarmonizomeFYCO1
DataMed IndexFYCO1
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFYCO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:10:07 CEST 2021

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