Identity
HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
CATC2,CTRCT18,RUFY3,ZFYVE7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79443
MIM: 607182
HGNC: 14673
Ensembl: ENSG00000163820
Variants:
dbSNP: 79443
ClinVar: 79443
TCGA: ENSG00000163820
COSMIC: FYCO1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163820 | ENST00000296137 | Q9BQS8 |
| ENSG00000163820 | ENST00000433878 | H7BZ74 |
| ENSG00000163820 | ENST00000438446 | C9J2W6 |
| ENSG00000163820 | ENST00000535325 | Q9BQS8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35638468 | 2022 | Targeted gene sequencing of FYCO1 identified a novel mutation in a Pakistani family for autosomal recessive congenital cataract. | 2 |
| 36061348 | 2022 | A Novel Mutation in the FYCO1 Gene Causing Congenital Cataract: Case Study of a Chinese Family. | 0 |
| 36342046 | 2022 | FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway. | 3 |
| 35638468 | 2022 | Targeted gene sequencing of FYCO1 identified a novel mutation in a Pakistani family for autosomal recessive congenital cataract. | 2 |
| 36061348 | 2022 | A Novel Mutation in the FYCO1 Gene Causing Congenital Cataract: Case Study of a Chinese Family. | 0 |
| 36342046 | 2022 | FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway. | 3 |
| 33649539 | 2021 | Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants. | 10 |
| 33767456 | 2021 | Autosomal recessive cataract (CTRCT18) in the Yakut population isolate of Eastern Siberia: a novel founder variant in the FYCO1 gene. | 7 |
| 33859171 | 2021 | Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1. | 10 |
| 34282983 | 2021 | Identification of a novel nonsense variant in FYCO1 gene associated with infantile cataract and cortical atrophy. | 3 |
| 33649539 | 2021 | Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants. | 10 |
| 33767456 | 2021 | Autosomal recessive cataract (CTRCT18) in the Yakut population isolate of Eastern Siberia: a novel founder variant in the FYCO1 gene. | 7 |
| 33859171 | 2021 | Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1. | 10 |
| 34282983 | 2021 | Identification of a novel nonsense variant in FYCO1 gene associated with infantile cataract and cortical atrophy. | 3 |
| 32744243 | 2020 | Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases. | 3 |
Citation
Dessen P
FYCO1 (FYVE and coiled-coil domain autophagy adaptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43868/fyco1
