Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FZD10 (frizzled class receptor 10)

Identity

Alias_namesfrizzled (Drosophila) homolog 10
frizzled homolog 10 (Drosophila)
frizzled 10, seven transmembrane spanning receptor
frizzled family receptor 10
Alias_symbol (synonym)CD350
Other aliasFZ-10
Fz10
FzE7
hFz10
HGNC (Hugo) FZD10
LocusID (NCBI) 11211
Atlas_Id 40654
Location 12q24.33  [Link to chromosome band 12q24]
Location_base_pair Starts at 130647004 and ends at 130650285 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Colon: Colorectal adenocarcinoma


External links

Nomenclature
HGNC (Hugo)FZD10   4039
Cards
Entrez_Gene (NCBI)FZD10  11211  frizzled class receptor 10
AliasesCD350; FZ-10; Fz10; FzE7; 
hFz10
GeneCards (Weizmann)FZD10
Ensembl hg19 (Hinxton)ENSG00000111432 [Gene_View]  chr12:130647004-130650285 [Contig_View]  FZD10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000111432 [Gene_View]  chr12:130647004-130650285 [Contig_View]  FZD10 [Vega]
ICGC DataPortalENSG00000111432
TCGA cBioPortalFZD10
AceView (NCBI)FZD10
Genatlas (Paris)FZD10
WikiGenes11211
SOURCE (Princeton)FZD10
Genetics Home Reference (NIH)FZD10
Genomic and cartography
GoldenPath hg19 (UCSC)FZD10  -     chr12:130647004-130650285 +  12q24.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FZD10  -     12q24.33   [Description]    (hg38-Dec_2013)
EnsemblFZD10 - 12q24.33 [CytoView hg19]  FZD10 - 12q24.33 [CytoView hg38]
Mapping of homologs : NCBIFZD10 [Mapview hg19]  FZD10 [Mapview hg38]
OMIM606147   
Gene and transcription
Genbank (Entrez)AB027464 AI697875 AL556202 BC070037 BC074997
RefSeq transcript (Entrez)NM_007197
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929386
Consensus coding sequences : CCDS (NCBI)FZD10
Cluster EST : UnigeneHs.733275 [ NCBI ]
CGAP (NCI)Hs.733275
Alternative Splicing GalleryENSG00000111432
Gene ExpressionFZD10 [ NCBI-GEO ]   FZD10 [ EBI - ARRAY_EXPRESS ]   FZD10 [ SEEK ]   FZD10 [ MEM ]
Gene Expression Viewer (FireBrowse)FZD10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11211
GTEX Portal (Tissue expression)FZD10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULW2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULW2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULW2
Splice isoforms : SwissVarQ9ULW2
PhosPhoSitePlusQ9ULW2
Domaine pattern : Prosite (Expaxy)FZ (PS50038)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (EBI)Frizzled    Frizzled/SFRP    Frizzled_dom    FZD10    GPCR_2-like   
Domain families : Pfam (Sanger)Frizzled (PF01534)    Fz (PF01392)   
Domain families : Pfam (NCBI)pfam01534    pfam01392   
Domain families : Smart (EMBL)FRI (SM00063)  
Conserved Domain (NCBI)FZD10
DMDM Disease mutations11211
Blocks (Seattle)FZD10
SuperfamilyQ9ULW2
Human Protein AtlasENSG00000111432
Peptide AtlasQ9ULW2
HPRD05853
IPIIPI00026973   IPI01015478   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULW2
IntAct (EBI)Q9ULW2
FunCoupENSG00000111432
BioGRIDFZD10
STRING (EMBL)FZD10
ZODIACFZD10
Ontologies - Pathways
QuickGOQ9ULW2
Ontology : AmiGOG-protein coupled receptor activity  protein binding  cytoplasm  integral component of plasma membrane  G-protein coupled receptor signaling pathway  cell surface  Wnt-protein binding  neuron differentiation  regulation of actin cytoskeleton organization  negative regulation of GTPase activity  non-canonical Wnt signaling pathway via JNK cascade  Wnt-activated receptor activity  positive regulation of JUN kinase activity  positive regulation of GTPase activity  canonical Wnt signaling pathway  cellular response to retinoic acid  
Ontology : EGO-EBIG-protein coupled receptor activity  protein binding  cytoplasm  integral component of plasma membrane  G-protein coupled receptor signaling pathway  cell surface  Wnt-protein binding  neuron differentiation  regulation of actin cytoskeleton organization  negative regulation of GTPase activity  non-canonical Wnt signaling pathway via JNK cascade  Wnt-activated receptor activity  positive regulation of JUN kinase activity  positive regulation of GTPase activity  canonical Wnt signaling pathway  cellular response to retinoic acid  
Pathways : KEGGWnt signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx NetworkFZD10
Atlas of Cancer Signalling NetworkFZD10
Wikipedia pathwaysFZD10
Orthology - Evolution
OrthoDB11211
GeneTree (enSembl)ENSG00000111432
Phylogenetic Trees/Animal Genes : TreeFamFZD10
HOVERGENQ9ULW2
HOGENOMQ9ULW2
Homologs : HomoloGeneFZD10
Homology/Alignments : Family Browser (UCSC)FZD10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFZD10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FZD10
dbVarFZD10
ClinVarFZD10
1000_GenomesFZD10 
Exome Variant ServerFZD10
ExAC (Exome Aggregation Consortium)FZD10 (select the gene name)
Genetic variants : HAPMAP11211
Genomic Variants (DGV)FZD10 [DGVbeta]
DECIPHER (Syndromes)12:130647004-130650285  ENSG00000111432
CONAN: Copy Number AnalysisFZD10 
Mutations
ICGC Data PortalFZD10 
TCGA Data PortalFZD10 
Broad Tumor PortalFZD10
OASIS PortalFZD10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFZD10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFZD10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FZD10
DgiDB (Drug Gene Interaction Database)FZD10
DoCM (Curated mutations)FZD10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FZD10 (select a term)
intoGenFZD10
Cancer3DFZD10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606147   
Orphanet
MedgenFZD10
Genetic Testing Registry FZD10
NextProtQ9ULW2 [Medical]
TSGene11211
GENETestsFZD10
Huge Navigator FZD10 [HugePedia]
snp3D : Map Gene to Disease11211
BioCentury BCIQFZD10
ClinGenFZD10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11211
Chemical/Pharm GKB GenePA28456
Clinical trialFZD10
Miscellaneous
canSAR (ICR)FZD10 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFZD10
EVEXFZD10
GoPubMedFZD10
iHOPFZD10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:06:48 CET 2017

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