Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FZD5 (frizzled class receptor 5)

Identity

Alias_namesC2orf31
frizzled (Drosophila) homolog 5
chromosome 2 open reading frame 31
frizzled homolog 5 (Drosophila)
frizzled 5, seven transmembrane spanning receptor
frizzled family receptor 5
Alias_symbol (synonym)HFZ5
DKFZP434E2135
Other alias
HGNC (Hugo) FZD5
LocusID (NCBI) 7855
Atlas_Id 47614
Location 2q33.3  [Link to chromosome band 2q33]
Location_base_pair Starts at 207762586 and ends at 207769419 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UBL3 (13q12.3) / FZD5 (2q33.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FZD5   4043
Cards
Entrez_Gene (NCBI)FZD5  7855  frizzled class receptor 5
AliasesC2orf31; HFZ5
GeneCards (Weizmann)FZD5
Ensembl hg19 (Hinxton)ENSG00000163251 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163251 [Gene_View]  chr2:207762586-207769419 [Contig_View]  FZD5 [Vega]
ICGC DataPortalENSG00000163251
TCGA cBioPortalFZD5
AceView (NCBI)FZD5
Genatlas (Paris)FZD5
WikiGenes7855
SOURCE (Princeton)FZD5
Genetics Home Reference (NIH)FZD5
Genomic and cartography
GoldenPath hg38 (UCSC)FZD5  -     chr2:207762586-207769419 -  2q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FZD5  -     2q33.3   [Description]    (hg19-Feb_2009)
EnsemblFZD5 - 2q33.3 [CytoView hg19]  FZD5 - 2q33.3 [CytoView hg38]
Mapping of homologs : NCBIFZD5 [Mapview hg19]  FZD5 [Mapview hg38]
OMIM601723   
Gene and transcription
Genbank (Entrez)AB043702 AK000125 AK024850 AK315338 AL136852
RefSeq transcript (Entrez)NM_003468 NM_030804
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FZD5
Cluster EST : UnigeneHs.17631 [ NCBI ]
CGAP (NCI)Hs.17631
Alternative Splicing GalleryENSG00000163251
Gene ExpressionFZD5 [ NCBI-GEO ]   FZD5 [ EBI - ARRAY_EXPRESS ]   FZD5 [ SEEK ]   FZD5 [ MEM ]
Gene Expression Viewer (FireBrowse)FZD5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7855
GTEX Portal (Tissue expression)FZD5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13467   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13467  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13467
Splice isoforms : SwissVarQ13467
PhosPhoSitePlusQ13467
Domaine pattern : Prosite (Expaxy)FZ (PS50038)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (EBI)Frizzled    Frizzled/SFRP    Frizzled_dom    FZD5    GPCR_2-like   
Domain families : Pfam (Sanger)Frizzled (PF01534)    Fz (PF01392)   
Domain families : Pfam (NCBI)pfam01534    pfam01392   
Domain families : Smart (EMBL)FRI (SM00063)  Frizzled (SM01330)  
Conserved Domain (NCBI)FZD5
DMDM Disease mutations7855
Blocks (Seattle)FZD5
SuperfamilyQ13467
Human Protein AtlasENSG00000163251
Peptide AtlasQ13467
HPRD03427
IPIIPI00298743   
Protein Interaction databases
DIP (DOE-UCLA)Q13467
IntAct (EBI)Q13467
FunCoupENSG00000163251
BioGRIDFZD5
STRING (EMBL)FZD5
ZODIACFZD5
Ontologies - Pathways
QuickGOQ13467
Ontology : AmiGOGolgi membrane  embryonic axis specification  angiogenesis  beta-amyloid binding  positive regulation of T cell cytokine production  G-protein coupled receptor activity  protein binding  early endosome  plasma membrane  bicellular tight junction  G-protein coupled receptor signaling pathway  Wnt signaling pathway, calcium modulating pathway  synapse assembly  negative regulation of cell proliferation  anterior/posterior axis specification, embryo  cell surface  integral component of membrane  Wnt-protein binding  protein kinase binding  neuron differentiation  clathrin-coated endocytic vesicle membrane  post-embryonic camera-type eye development  ubiquitin protein ligase binding  early endosome membrane  positive regulation of interferon-gamma production  T cell differentiation in thymus  Wnt-activated receptor activity  Wnt-activated receptor activity  positive regulation of JUN kinase activity  Wnt signaling pathway involved in dorsal/ventral axis specification  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  cell maturation  perinuclear region of cytoplasm  embryonic camera-type eye morphogenesis  Spemann organizer formation  canonical Wnt signaling pathway  canonical Wnt signaling pathway  Wnt signaling pathway, planar cell polarity pathway  apoptotic process involved in morphogenesis  branching involved in labyrinthine layer morphogenesis  syncytiotrophoblast cell differentiation involved in labyrinthine layer development  labyrinthine layer blood vessel development  chorionic trophoblast cell differentiation  regulation of canonical Wnt signaling pathway  cellular response to molecule of bacterial origin  regulation of chorionic trophoblast cell proliferation  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  beta-catenin destruction complex disassembly  regulation of bicellular tight junction assembly  
Ontology : EGO-EBIGolgi membrane  embryonic axis specification  angiogenesis  beta-amyloid binding  positive regulation of T cell cytokine production  G-protein coupled receptor activity  protein binding  early endosome  plasma membrane  bicellular tight junction  G-protein coupled receptor signaling pathway  Wnt signaling pathway, calcium modulating pathway  synapse assembly  negative regulation of cell proliferation  anterior/posterior axis specification, embryo  cell surface  integral component of membrane  Wnt-protein binding  protein kinase binding  neuron differentiation  clathrin-coated endocytic vesicle membrane  post-embryonic camera-type eye development  ubiquitin protein ligase binding  early endosome membrane  positive regulation of interferon-gamma production  T cell differentiation in thymus  Wnt-activated receptor activity  Wnt-activated receptor activity  positive regulation of JUN kinase activity  Wnt signaling pathway involved in dorsal/ventral axis specification  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  cell maturation  perinuclear region of cytoplasm  embryonic camera-type eye morphogenesis  Spemann organizer formation  canonical Wnt signaling pathway  canonical Wnt signaling pathway  Wnt signaling pathway, planar cell polarity pathway  apoptotic process involved in morphogenesis  branching involved in labyrinthine layer morphogenesis  syncytiotrophoblast cell differentiation involved in labyrinthine layer development  labyrinthine layer blood vessel development  chorionic trophoblast cell differentiation  regulation of canonical Wnt signaling pathway  cellular response to molecule of bacterial origin  regulation of chorionic trophoblast cell proliferation  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  beta-catenin destruction complex disassembly  regulation of bicellular tight junction assembly  
Pathways : KEGGWnt signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx NetworkFZD5
Atlas of Cancer Signalling NetworkFZD5
Wikipedia pathwaysFZD5
Orthology - Evolution
OrthoDB7855
GeneTree (enSembl)ENSG00000163251
Phylogenetic Trees/Animal Genes : TreeFamFZD5
HOVERGENQ13467
HOGENOMQ13467
Homologs : HomoloGeneFZD5
Homology/Alignments : Family Browser (UCSC)FZD5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFZD5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FZD5
dbVarFZD5
ClinVarFZD5
1000_GenomesFZD5 
Exome Variant ServerFZD5
ExAC (Exome Aggregation Consortium)FZD5 (select the gene name)
Genetic variants : HAPMAP7855
Genomic Variants (DGV)FZD5 [DGVbeta]
DECIPHERFZD5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFZD5 
Mutations
ICGC Data PortalFZD5 
TCGA Data PortalFZD5 
Broad Tumor PortalFZD5
OASIS PortalFZD5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFZD5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFZD5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FZD5
DgiDB (Drug Gene Interaction Database)FZD5
DoCM (Curated mutations)FZD5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FZD5 (select a term)
intoGenFZD5
Cancer3DFZD5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601723   
Orphanet13959    13964    13962    13963    13960    13961   
MedgenFZD5
Genetic Testing Registry FZD5
NextProtQ13467 [Medical]
TSGene7855
GENETestsFZD5
Target ValidationFZD5
Huge Navigator FZD5 [HugePedia]
snp3D : Map Gene to Disease7855
BioCentury BCIQFZD5
ClinGenFZD5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7855
Chemical/Pharm GKB GenePA28460
Clinical trialFZD5
Miscellaneous
canSAR (ICR)FZD5 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFZD5
EVEXFZD5
GoPubMedFZD5
iHOPFZD5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:09:10 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.