G2E3 (G2/M-phase specific E3 ubiquitin protein ligase)

2014-11-01  

Identity

HGNC
LOCATION
14q12
LOCUSID
ALIAS
KIAA1333,PHF7B
FUSION GENES

Other Information

Locus ID:

NCBI: 55632
MIM: 611299
HGNC: 20338
Ensembl: ENSG00000092140

Variants:

dbSNP: 55632
ClinVar: 55632
TCGA: ENSG00000092140
COSMIC: G2E3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092140ENST00000206595Q7L622
ENSG00000092140ENST00000438909F5GX24
ENSG00000092140ENST00000547532F8W0F5
ENSG00000092140ENST00000548934H0YH90
ENSG00000092140ENST00000550944F8VY49
ENSG00000092140ENST00000552515H0YI49
ENSG00000092140ENST00000553504G3V483
ENSG00000092140ENST00000554714G3V3B6
ENSG00000092140ENST00000555429G3V5B6
ENSG00000092140ENST00000648008A0A3B3ISH7

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
172393722007G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization.8
255931942015Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.4

Citation

Dessen P

G2E3 (G2/M-phase specific E3 ubiquitin protein ligase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63638/g2e3