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G2E3 (G2/M-phase specific E3 ubiquitin protein ligase)

Identity

Alias_namesKIAA1333
KIAA1333
Alias_symbol (synonym)FLJ20333
PHF7B
Other alias
HGNC (Hugo) G2E3
LocusID (NCBI) 55632
Atlas_Id 63638
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 30559123 and ends at 30620061 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
G2E3 (14q12) / UBR3 (2q31.1)SPRED2 (2p14) / G2E3 (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)G2E3   20338
Cards
Entrez_Gene (NCBI)G2E3  55632  G2/M-phase specific E3 ubiquitin protein ligase
AliasesKIAA1333; PHF7B
GeneCards (Weizmann)G2E3
Ensembl hg19 (Hinxton)ENSG00000092140 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092140 [Gene_View]  chr14:30559123-30620061 [Contig_View]  G2E3 [Vega]
ICGC DataPortalENSG00000092140
TCGA cBioPortalG2E3
AceView (NCBI)G2E3
Genatlas (Paris)G2E3
WikiGenes55632
SOURCE (Princeton)G2E3
Genetics Home Reference (NIH)G2E3
Genomic and cartography
GoldenPath hg38 (UCSC)G2E3  -     chr14:30559123-30620061 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)G2E3  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblG2E3 - 14q12 [CytoView hg19]  G2E3 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIG2E3 [Mapview hg19]  G2E3 [Mapview hg38]
OMIM611299   
Gene and transcription
Genbank (Entrez)AB037754 AI432917 AK000340 AK022867 AK093536
RefSeq transcript (Entrez)NM_001308097 NM_017769
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)G2E3
Cluster EST : UnigeneHs.605081 [ NCBI ]
CGAP (NCI)Hs.605081
Alternative Splicing GalleryENSG00000092140
Gene ExpressionG2E3 [ NCBI-GEO ]   G2E3 [ EBI - ARRAY_EXPRESS ]   G2E3 [ SEEK ]   G2E3 [ MEM ]
Gene Expression Viewer (FireBrowse)G2E3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55632
GTEX Portal (Tissue expression)G2E3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L622   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L622  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L622
Splice isoforms : SwissVarQ7L622
Catalytic activity : Enzyme2.3.2.26 [ Enzyme-Expasy ]   2.3.2.262.3.2.26 [ IntEnz-EBI ]   2.3.2.26 [ BRENDA ]   2.3.2.26 [ KEGG ]   
PhosPhoSitePlusQ7L622
Domaine pattern : Prosite (Expaxy)EPHD (PS51805)    HECT (PS50237)    ZF_PHD_1 (PS01359)   
Domains : Interpro (EBI)HECT_dom    Zinc_finger_PHD-type_CS    Znf_FYVE_PHD    Znf_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)HECT (PF00632)   
Domain families : Pfam (NCBI)pfam00632   
Domain families : Smart (EMBL)HECTc (SM00119)  PHD (SM00249)  
Conserved Domain (NCBI)G2E3
DMDM Disease mutations55632
Blocks (Seattle)G2E3
SuperfamilyQ7L622
Human Protein AtlasENSG00000092140
Peptide AtlasQ7L622
HPRD13851
IPIIPI00479641   IPI00909866   IPI01014463   IPI00640023   IPI01021366   IPI01021835   IPI01021696   IPI01022079   IPI01021024   IPI01025999   IPI01026109   IPI01026129   
Protein Interaction databases
DIP (DOE-UCLA)Q7L622
IntAct (EBI)Q7L622
FunCoupENSG00000092140
BioGRIDG2E3
STRING (EMBL)G2E3
ZODIACG2E3
Ontologies - Pathways
QuickGOQ7L622
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleolus  cytoplasm  apoptotic process  multicellular organism development  zinc ion binding  protein ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleolus  cytoplasm  apoptotic process  multicellular organism development  zinc ion binding  protein ubiquitination  
NDEx NetworkG2E3
Atlas of Cancer Signalling NetworkG2E3
Wikipedia pathwaysG2E3
Orthology - Evolution
OrthoDB55632
GeneTree (enSembl)ENSG00000092140
Phylogenetic Trees/Animal Genes : TreeFamG2E3
HOVERGENQ7L622
HOGENOMQ7L622
Homologs : HomoloGeneG2E3
Homology/Alignments : Family Browser (UCSC)G2E3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerG2E3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)G2E3
dbVarG2E3
ClinVarG2E3
1000_GenomesG2E3 
Exome Variant ServerG2E3
ExAC (Exome Aggregation Consortium)G2E3 (select the gene name)
Genetic variants : HAPMAP55632
Genomic Variants (DGV)G2E3 [DGVbeta]
DECIPHERG2E3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisG2E3 
Mutations
ICGC Data PortalG2E3 
TCGA Data PortalG2E3 
Broad Tumor PortalG2E3
OASIS PortalG2E3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICG2E3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDG2E3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch G2E3
DgiDB (Drug Gene Interaction Database)G2E3
DoCM (Curated mutations)G2E3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)G2E3 (select a term)
intoGenG2E3
Cancer3DG2E3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611299   
Orphanet
MedgenG2E3
Genetic Testing Registry G2E3
NextProtQ7L622 [Medical]
TSGene55632
GENETestsG2E3
Target ValidationG2E3
Huge Navigator G2E3 [HugePedia]
snp3D : Map Gene to Disease55632
BioCentury BCIQG2E3
ClinGenG2E3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55632
Chemical/Pharm GKB GenePA164720127
Clinical trialG2E3
Miscellaneous
canSAR (ICR)G2E3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineG2E3
EVEXG2E3
GoPubMedG2E3
iHOPG2E3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:50:05 CEST 2017

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