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G3BP1 (GTPase activating protein (SH3 domain) binding protein 1)

Identity

Other namesG3BP
HDH-VIII
HGNC (Hugo) G3BP1
LocusID (NCBI) 10146
Location 5q33.1
Location_base_pair Starts at 151151476 and ends at 151184915 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)G3BP1   30292
Entrez_Gene (NCBI)G3BP1  10146  GTPase activating protein (SH3 domain) binding protein 1
Cards
GeneCards (Weizmann)G3BP1
Ensembl (Hinxton)ENSG00000145907 [Gene_View]  chr5:151151476-151184915 [Contig_View]  G3BP1 [Vega]
AceView (NCBI)G3BP1
Genatlas (Paris)G3BP1
SOURCE (Stanford)NM_005754 NM_198395
Genomic and cartography
GoldenPath (UCSC)G3BP1  -  5q33.1   chr5:151151476-151184915 +  5q33.1   [Description]    (hg19-Feb_2009)
EnsemblG3BP1 - 5q33.1 [CytoView]
Mapping of homologs : NCBIG3BP1 [Mapview]
OMIM608431   
Gene and transcription
Genbank (Entrez)AK091592 AK130003 AK222606 AK300098 AK303580
RefSeq transcript (SRS)NM_005754 NM_198395
RefSeq transcript (Entrez)NM_005754 NM_198395
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NT_029289 NW_001838953 NW_004078025
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NT_029289 NW_001838953 NW_004078025
Consensus coding sequences : CCDS (NCBI)G3BP1
Cluster EST : UnigeneHs.587054 [ SRS ] Hs.587054 [ NCBI ]
CGAP (NCI)Hs.587054
Alternative Splicing : Fast-db (Paris)GSHG0024385
Alternative Splicing GalleryENSG00000145907
Gene ExpressionG3BP1 [ NCBI-GEO ]   G3BP1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13283 (SRS) Q13283 (Uniprot)
NextProtQ13283
With graphics : InterProQ13283
Splice isoforms : SwissVarQ13283(Swissvar)
Domaine pattern : Prosite (SRS)NTF2_DOMAIN (PS50177)    RRM (PS50102)   
Domaine pattern : Prosite (Expaxy)NTF2_DOMAIN (PS50177)    RRM (PS50102)   
Domains : Interpro (SRS)NTF2    Nuclear_transport_factor_2_euk    Nucleotide-bd_a/b_plait    RRM_dom   
Domains : Interpro (EBI)NTF2    Nuclear_transport_factor_2_euk    Nucleotide-bd_a/b_plait    RRM_dom   
Related proteins : CluSTrQ13283
Domain families : Pfam (SRS)NTF2 (PF02136)    RRM_1 (PF00076)   
Domain families : Pfam (Sanger)NTF2 (PF02136)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam02136    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
DMDM10146
Blocks (Seattle)Q13283
PDB (SRS)3Q90   
PDB (PDBSum)3Q90   
PDB (IMB)3Q90   
PDB (RSDB)3Q90   
Human Protein AtlasENSG00000145907
HPRD06569
IPIIPI00012442   IPI01011685   IPI00442863   IPI00977369   IPI00973731   IPI00982147   IPI00982712   IPI00979451   IPI00974560   IPI00973932   IPI00982785   
Protein Interaction databases
DIP (DOE-UCLA)Q13283
IntAct (EBI)Q13283
FunCoupENSG00000145907
REACTOMEG3BP1
Protein Interaction Database10146
BioGRIDG3BP1
InParanoidQ13283
Interologous Interaction database Q13283
IntegromeDBG3BP1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)G3BP1
SNP (GeneSNP Utah)G3BP1
SNP : HGBaseG3BP1
Genetic variants : HAPMAPG3BP1
Somatic Mutations in Cancer : COSMICG3BP1 
CONAN: Copy Number AnalysisG3BP1 
Mutations and Diseases : HGMDG3BP1
OMIM608431   
GENETests608431   
Disease Genetic AssociationG3BP1
Huge Navigator G3BP1 [HugePedia]  G3BP1 [HugeCancerGEM]
Genomic VariantsG3BP1  G3BP1 [DGVbeta]
ClinVarG3BP1
snp3D : Map Gene to Disease10146
General knowledge
Homologs : HomoloGeneG3BP1
Homology/Alignments : Family Browser (UCSC)G3BP1
Phylogenetic Trees/Animal Genes : TreeFamG3BP1
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.12 [ Enzyme-SRS ]   3.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
Chemical/Protein Interactions : CTD10146
Chemical/Pharm GKB GenePA162389105
Clinical trialG3BP1
Cancer Resource (Charite)ENSG00000145907
Ontology : AmiGODNA binding  mRNA binding  ATP-dependent DNA helicase activity  ATP-dependent RNA helicase activity  endonuclease activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  plasma membrane  transport  Ras protein signal transduction  cytoplasmic stress granule  negative regulation of canonical Wnt receptor signaling pathway  
Ontology : EGO-EBIDNA binding  mRNA binding  ATP-dependent DNA helicase activity  ATP-dependent RNA helicase activity  endonuclease activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  plasma membrane  transport  Ras protein signal transduction  cytoplasmic stress granule  negative regulation of canonical Wnt receptor signaling pathway  
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
PubGeneG3BP1
iHOPG3BP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:59:22 CEST 2013
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