Atlas of Genetics and Cytogenetics in Oncology and Haematology


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G6PC (glucose-6-phosphatase, catalytic subunit)

Identity

Other namesG6PC1
G6PT
GSD1
GSD1a
HGNC (Hugo) G6PC
LocusID (NCBI) 2538
Location 17q21.31
Location_base_pair Starts at 41052814 and ends at 41066450 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)G6PC   4056
Cards
Entrez_Gene (NCBI)G6PC  2538  glucose-6-phosphatase, catalytic subunit
GeneCards (Weizmann)G6PC
Ensembl (Hinxton) [Gene_View]  chr17:41052814-41066450 [Contig_View]  G6PC [Vega]
cBioPortalG6PC
AceView (NCBI)G6PC
Genatlas (Paris)G6PC
WikiGenes2538
SOURCE (Princeton)NM_000151 NM_001270397
Genomic and cartography
GoldenPath (UCSC)G6PC  -  17q21.31   chr17:41052814-41066450 +  17q21.31   [Description]    (hg19-Feb_2009)
EnsemblG6PC - 17q21.31 [CytoView]
Mapping of homologs : NCBIG6PC [Mapview]
OMIM232200   613742   
Gene and transcription
Genbank (Entrez)AK303771 AK313982 AW614228 BC130478 BC136369
RefSeq transcript (Entrez)NM_000151 NM_001270397
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_011808 NT_010783 NW_001838436 NW_004929407
Consensus coding sequences : CCDS (NCBI)G6PC
Cluster EST : UnigeneHs.742566 [ NCBI ]
CGAP (NCI)Hs.742566
Alternative Splicing : Fast-db (Paris)GSHG0012525
Gene ExpressionG6PC [ NCBI-GEO ]     G6PC [ SEEK ]   G6PC [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35575 (Uniprot)
NextProtP35575  [Medical]
With graphics : InterProP35575
Splice isoforms : SwissVarP35575 (Swissvar)
Catalytic activity : Enzyme3.1.3.9 [ Enzyme-Expasy ]   3.1.3.93.1.3.9 [ IntEnz-EBI ]   3.1.3.9 [ BRENDA ]   3.1.3.9 [ KEGG ]   
Domains : Interpro (EBI)Glucose-6-phosphatase [organisation]   P_Acid_Pase_2/haloperoxidase [organisation]  
Related proteins : CluSTrP35575
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
DMDM Disease mutations2538
Blocks (Seattle)P35575
Peptide AtlasP35575
HPRD01983
IPIIPI00910642   IPI00019500   
Protein Interaction databases
DIP (DOE-UCLA)P35575
IntAct (EBI)P35575
BioGRIDG6PC
InParanoidP35575
Interologous Interaction database P35575
IntegromeDBG6PC
STRING (EMBL)G6PC
Ontologies - Pathways
Ontology : AmiGOglucose-6-phosphatase activity  endoplasmic reticulum membrane  carbohydrate metabolic process  glycogen metabolic process  glycogen catabolic process  gluconeogenesis  gluconeogenesis  triglyceride metabolic process  steroid metabolic process  hexose transport  regulation of gene expression  glucose transport  glucose-6-phosphate transport  integral component of membrane  dephosphorylation  dephosphorylation  phosphotransferase activity, alcohol group as acceptor  integral component of endoplasmic reticulum membrane  multicellular organism growth  phosphate ion binding  glucose homeostasis  cholesterol homeostasis  small molecule metabolic process  urate metabolic process  glucose 6-phosphate metabolic process  transmembrane transport  
Ontology : EGO-EBIglucose-6-phosphatase activity  endoplasmic reticulum membrane  carbohydrate metabolic process  glycogen metabolic process  glycogen catabolic process  gluconeogenesis  gluconeogenesis  triglyceride metabolic process  steroid metabolic process  hexose transport  regulation of gene expression  glucose transport  glucose-6-phosphate transport  integral component of membrane  dephosphorylation  dephosphorylation  phosphotransferase activity, alcohol group as acceptor  integral component of endoplasmic reticulum membrane  multicellular organism growth  phosphate ion binding  glucose homeostasis  cholesterol homeostasis  small molecule metabolic process  urate metabolic process  glucose 6-phosphate metabolic process  transmembrane transport  
Pathways : KEGGGlycolysis / Gluconeogenesis    Galactose metabolism    Starch and sucrose metabolism    FoxO signaling pathway    PI3K-Akt signaling pathway    Insulin signaling pathway    Adipocytokine signaling pathway    Carbohydrate digestion and absorption   
Protein Interaction DatabaseG6PC
Wikipedia pathwaysG6PC
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)G6PC
snp3D : Map Gene to Disease2538
SNP (GeneSNP Utah)G6PC
SNP : HGBaseG6PC
Genetic variants : HAPMAPG6PC
Exome VariantG6PC
1000_GenomesG6PC 
Somatic Mutations in Cancer : COSMICG6PC 
CONAN: Copy Number AnalysisG6PC 
Mutations and Diseases : HGMDG6PC
Mutations and Diseases : intOGenG6PC
Genomic VariantsG6PC  G6PC [DGVbeta]
dbVarG6PC
ClinVarG6PC
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM232200    613742   
MedgenG6PC
GENETestsG6PC
Disease Genetic AssociationG6PC
Huge Navigator G6PC [HugePedia]  G6PC [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneG6PC
Homology/Alignments : Family Browser (UCSC)G6PC
Phylogenetic Trees/Animal Genes : TreeFamG6PC
Chemical/Protein Interactions : CTD2538
Chemical/Pharm GKB GenePA28468
Clinical trialG6PC
Other databases
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
CoreMineG6PC
iHOPG6PC
OncoSearchG6PC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:47:34 CEST 2014

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