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G6PC2 (glucose-6-phosphatase catalytic subunit 2)

Identity

Alias_namesglucose-6-phosphatase, catalytic, 2
Alias_symbol (synonym)IGRP
Other alias
HGNC (Hugo) G6PC2
LocusID (NCBI) 57818
Atlas_Id 63639
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 168901240 and ends at 168910000 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
G6PC2 (2q31.1) / CAT (11p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)G6PC2   28906
Cards
Entrez_Gene (NCBI)G6PC2  57818  glucose-6-phosphatase catalytic subunit 2
AliasesIGRP
GeneCards (Weizmann)G6PC2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:168901240-168910000 [Contig_View]  G6PC2 [Vega]
TCGA cBioPortalG6PC2
AceView (NCBI)G6PC2
Genatlas (Paris)G6PC2
WikiGenes57818
SOURCE (Princeton)G6PC2
Genetics Home Reference (NIH)G6PC2
Genomic and cartography
GoldenPath hg38 (UCSC)G6PC2  -     chr2:168901240-168910000 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)G6PC2  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblG6PC2 - 2q31.1 [CytoView hg19]  G6PC2 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIG6PC2 [Mapview hg19]  G6PC2 [Mapview hg38]
OMIM608058   
Gene and transcription
Genbank (Entrez)AK310853 BC104778 BC113376 BQ268961 CA865646
RefSeq transcript (Entrez)NM_001081686 NM_021176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)G6PC2
Cluster EST : UnigeneHs.283963 [ NCBI ]
CGAP (NCI)Hs.283963
Gene ExpressionG6PC2 [ NCBI-GEO ]   G6PC2 [ EBI - ARRAY_EXPRESS ]   G6PC2 [ SEEK ]   G6PC2 [ MEM ]
Gene Expression Viewer (FireBrowse)G6PC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57818
GTEX Portal (Tissue expression)G6PC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQR9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQR9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQR9
Splice isoforms : SwissVarQ9NQR9
Catalytic activity : Enzyme3.1.3.9 [ Enzyme-Expasy ]   3.1.3.93.1.3.9 [ IntEnz-EBI ]   3.1.3.9 [ BRENDA ]   3.1.3.9 [ KEGG ]   
PhosPhoSitePlusQ9NQR9
Domains : Interpro (EBI)Glucose-6-phosphatase    P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)G6PC2
DMDM Disease mutations57818
Blocks (Seattle)G6PC2
SuperfamilyQ9NQR9
Peptide AtlasQ9NQR9
HPRD16272
IPIIPI00028155   IPI00465025   IPI00830064   IPI00927598   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQR9
IntAct (EBI)Q9NQR9
BioGRIDG6PC2
STRING (EMBL)G6PC2
ZODIACG6PC2
Ontologies - Pathways
QuickGOQ9NQR9
Ontology : AmiGOglucose-6-phosphatase activity  glucose-6-phosphatase activity  endoplasmic reticulum membrane  gluconeogenesis  gluconeogenesis  glucose transport  dephosphorylation  integral component of endoplasmic reticulum membrane  glucose homeostasis  regulation of insulin secretion  glucose 6-phosphate metabolic process  
Ontology : EGO-EBIglucose-6-phosphatase activity  glucose-6-phosphatase activity  endoplasmic reticulum membrane  gluconeogenesis  gluconeogenesis  glucose transport  dephosphorylation  integral component of endoplasmic reticulum membrane  glucose homeostasis  regulation of insulin secretion  glucose 6-phosphate metabolic process  
Pathways : KEGGGlycolysis / Gluconeogenesis    Galactose metabolism    Starch and sucrose metabolism    FoxO signaling pathway    PI3K-Akt signaling pathway    Insulin signaling pathway    Adipocytokine signaling pathway    Carbohydrate digestion and absorption   
NDEx NetworkG6PC2
Atlas of Cancer Signalling NetworkG6PC2
Wikipedia pathwaysG6PC2
Orthology - Evolution
OrthoDB57818
Phylogenetic Trees/Animal Genes : TreeFamG6PC2
HOVERGENQ9NQR9
HOGENOMQ9NQR9
Homologs : HomoloGeneG6PC2
Homology/Alignments : Family Browser (UCSC)G6PC2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerG6PC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)G6PC2
dbVarG6PC2
ClinVarG6PC2
1000_GenomesG6PC2 
Exome Variant ServerG6PC2
ExAC (Exome Aggregation Consortium)G6PC2 (select the gene name)
Genetic variants : HAPMAP57818
Genomic Variants (DGV)G6PC2 [DGVbeta]
DECIPHERG6PC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisG6PC2 
Mutations
ICGC Data PortalG6PC2 
TCGA Data PortalG6PC2 
Broad Tumor PortalG6PC2
OASIS PortalG6PC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICG6PC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDG6PC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch G6PC2
DgiDB (Drug Gene Interaction Database)G6PC2
DoCM (Curated mutations)G6PC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)G6PC2 (select a term)
intoGenG6PC2
Cancer3DG6PC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608058   
Orphanet
MedgenG6PC2
Genetic Testing Registry G6PC2
NextProtQ9NQR9 [Medical]
TSGene57818
GENETestsG6PC2
Target ValidationG6PC2
Huge Navigator G6PC2 [HugePedia]
snp3D : Map Gene to Disease57818
BioCentury BCIQG6PC2
ClinGenG6PC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57818
Chemical/Pharm GKB GenePA134944773
Clinical trialG6PC2
Miscellaneous
canSAR (ICR)G6PC2 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineG6PC2
EVEXG6PC2
GoPubMedG6PC2
iHOPG6PC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:09:02 CEST 2017

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