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G6PC3 (glucose-6-phosphatase catalytic subunit 3)

Identity

Alias_namesglucose 6 phosphatase
Alias_symbol (synonym)UGRP
Other aliasSCN4
HGNC (Hugo) G6PC3
LocusID (NCBI) 92579
Atlas_Id 52724
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 44070730 and ends at 44076344 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COTL1 (16q24.1) / G6PC3 (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)G6PC3   24861
LRG (Locus Reference Genomic)LRG_182
Cards
Entrez_Gene (NCBI)G6PC3  92579  glucose-6-phosphatase catalytic subunit 3
AliasesSCN4; UGRP
GeneCards (Weizmann)G6PC3
Ensembl hg19 (Hinxton)ENSG00000141349 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000141349 [Gene_View]  chr17:44070730-44076344 [Contig_View]  G6PC3 [Vega]
ICGC DataPortalENSG00000141349
TCGA cBioPortalG6PC3
AceView (NCBI)G6PC3
Genatlas (Paris)G6PC3
WikiGenes92579
SOURCE (Princeton)G6PC3
Genetics Home Reference (NIH)G6PC3
Genomic and cartography
GoldenPath hg38 (UCSC)G6PC3  -     chr17:44070730-44076344 +  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)G6PC3  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblG6PC3 - 17q21.31 [CytoView hg19]  G6PC3 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIG6PC3 [Mapview hg19]  G6PC3 [Mapview hg38]
OMIM611045   612541   
Gene and transcription
Genbank (Entrez)BC002494 BC021574 BC062596 BM790097 DB460416
RefSeq transcript (Entrez)NM_001319945 NM_138387
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)G6PC3
Cluster EST : UnigeneHs.294005 [ NCBI ]
CGAP (NCI)Hs.294005
Alternative Splicing GalleryENSG00000141349
Gene ExpressionG6PC3 [ NCBI-GEO ]   G6PC3 [ EBI - ARRAY_EXPRESS ]   G6PC3 [ SEEK ]   G6PC3 [ MEM ]
Gene Expression Viewer (FireBrowse)G6PC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92579
GTEX Portal (Tissue expression)G6PC3
Human Protein AtlasENSG00000141349-G6PC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUM1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUM1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUM1
Splice isoforms : SwissVarQ9BUM1
Catalytic activity : Enzyme3.1.3.9 [ Enzyme-Expasy ]   3.1.3.93.1.3.9 [ IntEnz-EBI ]   3.1.3.9 [ BRENDA ]   3.1.3.9 [ KEGG ]   
PhosPhoSitePlusQ9BUM1
Domains : Interpro (EBI)Glucose-6-phosphatase    P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)G6PC3
DMDM Disease mutations92579
Blocks (Seattle)G6PC3
SuperfamilyQ9BUM1
Human Protein Atlas [tissue]ENSG00000141349-G6PC3 [tissue]
Peptide AtlasQ9BUM1
HPRD13556
IPIIPI00031052   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUM1
IntAct (EBI)Q9BUM1
FunCoupENSG00000141349
BioGRIDG6PC3
STRING (EMBL)G6PC3
ZODIACG6PC3
Ontologies - Pathways
QuickGOQ9BUM1
Ontology : AmiGOglucose-6-phosphatase activity  glucose-6-phosphatase activity  endoplasmic reticulum  endoplasmic reticulum membrane  gluconeogenesis  gluconeogenesis  glucose transport  glucose-6-phosphate transport  membrane  dephosphorylation  integral component of endoplasmic reticulum membrane  glucose 6-phosphate metabolic process  
Ontology : EGO-EBIglucose-6-phosphatase activity  glucose-6-phosphatase activity  endoplasmic reticulum  endoplasmic reticulum membrane  gluconeogenesis  gluconeogenesis  glucose transport  glucose-6-phosphate transport  membrane  dephosphorylation  integral component of endoplasmic reticulum membrane  glucose 6-phosphate metabolic process  
Pathways : KEGG   
NDEx NetworkG6PC3
Atlas of Cancer Signalling NetworkG6PC3
Wikipedia pathwaysG6PC3
Orthology - Evolution
OrthoDB92579
GeneTree (enSembl)ENSG00000141349
Phylogenetic Trees/Animal Genes : TreeFamG6PC3
HOVERGENQ9BUM1
HOGENOMQ9BUM1
Homologs : HomoloGeneG6PC3
Homology/Alignments : Family Browser (UCSC)G6PC3
Gene fusions - Rearrangements
Tumor Fusion PortalG6PC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerG6PC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)G6PC3
dbVarG6PC3
ClinVarG6PC3
1000_GenomesG6PC3 
Exome Variant ServerG6PC3
ExAC (Exome Aggregation Consortium)ENSG00000141349
GNOMAD BrowserENSG00000141349
Genetic variants : HAPMAP92579
Genomic Variants (DGV)G6PC3 [DGVbeta]
DECIPHERG6PC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisG6PC3 
Mutations
ICGC Data PortalG6PC3 
TCGA Data PortalG6PC3 
Broad Tumor PortalG6PC3
OASIS PortalG6PC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICG6PC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDG6PC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch G6PC3
DgiDB (Drug Gene Interaction Database)G6PC3
DoCM (Curated mutations)G6PC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)G6PC3 (select a term)
intoGenG6PC3
Cancer3DG6PC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611045    612541   
Orphanet21992   
DisGeNETG6PC3
MedgenG6PC3
Genetic Testing Registry G6PC3
NextProtQ9BUM1 [Medical]
TSGene92579
GENETestsG6PC3
Target ValidationG6PC3
Huge Navigator G6PC3 [HugePedia]
snp3D : Map Gene to Disease92579
BioCentury BCIQG6PC3
ClinGenG6PC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92579
Chemical/Pharm GKB GenePA134968446
Clinical trialG6PC3
Miscellaneous
canSAR (ICR)G6PC3 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineG6PC3
EVEXG6PC3
GoPubMedG6PC3
iHOPG6PC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:14:00 CET 2017

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