Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GABARAP (GABA type A receptor-associated protein)

Identity

Alias_namesGABA(A) receptor-associated protein
Alias_symbol (synonym)MM46
ATG8A
Other aliasGABARAP-a
HGNC (Hugo) GABARAP
LocusID (NCBI) 11337
Atlas_Id 43973
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 7240419 and ends at 7242434 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C2orf57 (2q37.1) / GABARAP (17p13.1)GABARAP (17p13.1) / GABARAP (17p13.1)GABARAP (17p13.1) / PHF23 (17p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GABARAP   4067
Cards
Entrez_Gene (NCBI)GABARAP  11337  GABA type A receptor-associated protein
AliasesATG8A; GABARAP-a; MM46
GeneCards (Weizmann)GABARAP
Ensembl hg19 (Hinxton)ENSG00000170296 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170296 [Gene_View]  chr17:7240419-7242434 [Contig_View]  GABARAP [Vega]
ICGC DataPortalENSG00000170296
TCGA cBioPortalGABARAP
AceView (NCBI)GABARAP
Genatlas (Paris)GABARAP
WikiGenes11337
SOURCE (Princeton)GABARAP
Genetics Home Reference (NIH)GABARAP
Genomic and cartography
GoldenPath hg38 (UCSC)GABARAP  -     chr17:7240419-7242434 -  17p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GABARAP  -     17p13.1   [Description]    (hg19-Feb_2009)
EnsemblGABARAP - 17p13.1 [CytoView hg19]  GABARAP - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIGABARAP [Mapview hg19]  GABARAP [Mapview hg38]
OMIM605125   
Gene and transcription
Genbank (Entrez)AB030711 AF044671 AF067171 AF161586 AF183425
RefSeq transcript (Entrez)NM_007278
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GABARAP
Cluster EST : UnigeneHs.647421 [ NCBI ]
CGAP (NCI)Hs.647421
Alternative Splicing GalleryENSG00000170296
Gene ExpressionGABARAP [ NCBI-GEO ]   GABARAP [ EBI - ARRAY_EXPRESS ]   GABARAP [ SEEK ]   GABARAP [ MEM ]
Gene Expression Viewer (FireBrowse)GABARAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11337
GTEX Portal (Tissue expression)GABARAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95166   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95166  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95166
Splice isoforms : SwissVarO95166
PhosPhoSitePlusO95166
Domains : Interpro (EBI)Atg8-like    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)Atg8 (PF02991)   
Domain families : Pfam (NCBI)pfam02991   
Conserved Domain (NCBI)GABARAP
DMDM Disease mutations11337
Blocks (Seattle)GABARAP
PDB (SRS)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
PDB (PDBSum)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
PDB (IMB)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
PDB (RSDB)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
Structural Biology KnowledgeBase1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
SCOP (Structural Classification of Proteins)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
CATH (Classification of proteins structures)1GNU    1KLV    1KM7    1KOT    3D32    3DOW    3WIM    4XC2    5DPS   
SuperfamilyO95166
Human Protein AtlasENSG00000170296
Peptide AtlasO95166
HPRD05496
IPIIPI00027253   
Protein Interaction databases
DIP (DOE-UCLA)O95166
IntAct (EBI)O95166
FunCoupENSG00000170296
BioGRIDGABARAP
STRING (EMBL)GABARAP
ZODIACGABARAP
Ontologies - Pathways
QuickGOO95166
Ontology : AmiGOGolgi membrane  microtubule cytoskeleton organization  autophagosome membrane  autophagosome membrane  protein binding  lysosome  autophagosome  smooth endoplasmic reticulum  cytosol  microtubule  microtubule associated complex  plasma membrane  axoneme  protein targeting  chemical synaptic transmission  microtubule binding  extrinsic apoptotic signaling pathway via death domain receptors  actin cytoskeleton  macroautophagy  cytoplasmic vesicle  ubiquitin protein ligase binding  cell body  perinuclear region of cytoplasm  beta-tubulin binding  GABA receptor binding  membrane organization  sperm midpiece  autophagosome maturation  
Ontology : EGO-EBIGolgi membrane  microtubule cytoskeleton organization  autophagosome membrane  autophagosome membrane  protein binding  lysosome  autophagosome  smooth endoplasmic reticulum  cytosol  microtubule  microtubule associated complex  plasma membrane  axoneme  protein targeting  chemical synaptic transmission  microtubule binding  extrinsic apoptotic signaling pathway via death domain receptors  actin cytoskeleton  macroautophagy  cytoplasmic vesicle  ubiquitin protein ligase binding  cell body  perinuclear region of cytoplasm  beta-tubulin binding  GABA receptor binding  membrane organization  sperm midpiece  autophagosome maturation  
Pathways : BIOCARTAGamma-aminobutyric Acid Receptor Life Cycle [Genes]   
Pathways : KEGGFoxO signaling pathway    Regulation of autophagy    GABAergic synapse   
NDEx NetworkGABARAP
Atlas of Cancer Signalling NetworkGABARAP
Wikipedia pathwaysGABARAP
Orthology - Evolution
OrthoDB11337
GeneTree (enSembl)ENSG00000170296
Phylogenetic Trees/Animal Genes : TreeFamGABARAP
HOVERGENO95166
HOGENOMO95166
Homologs : HomoloGeneGABARAP
Homology/Alignments : Family Browser (UCSC)GABARAP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGABARAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GABARAP
dbVarGABARAP
ClinVarGABARAP
1000_GenomesGABARAP 
Exome Variant ServerGABARAP
ExAC (Exome Aggregation Consortium)GABARAP (select the gene name)
Genetic variants : HAPMAP11337
Genomic Variants (DGV)GABARAP [DGVbeta]
DECIPHERGABARAP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGABARAP 
Mutations
ICGC Data PortalGABARAP 
TCGA Data PortalGABARAP 
Broad Tumor PortalGABARAP
OASIS PortalGABARAP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGABARAP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGABARAP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GABARAP
DgiDB (Drug Gene Interaction Database)GABARAP
DoCM (Curated mutations)GABARAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GABARAP (select a term)
intoGenGABARAP
Cancer3DGABARAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605125   
Orphanet
MedgenGABARAP
Genetic Testing Registry GABARAP
NextProtO95166 [Medical]
TSGene11337
GENETestsGABARAP
Target ValidationGABARAP
Huge Navigator GABARAP [HugePedia]
snp3D : Map Gene to Disease11337
BioCentury BCIQGABARAP
ClinGenGABARAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11337
Chemical/Pharm GKB GenePA28480
Clinical trialGABARAP
Miscellaneous
canSAR (ICR)GABARAP (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGABARAP
EVEXGABARAP
GoPubMedGABARAP
iHOPGABARAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:40 CEST 2017

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