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GABPB1 (GA binding protein transcription factor, beta subunit 1)

Identity

Alias_namesGABPB2
GA binding protein transcription factor, beta subunit 2
Alias_symbol (synonym)E4TF1-47
GABPB
Other aliasBABPB2
E4TF1
E4TF1-53
E4TF1B
NRF2B1
NRF2B2
HGNC (Hugo) GABPB1
LocusID (NCBI) 2553
Atlas_Id 63644
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 50578077 and ends at 50647605 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GABPB1 (15q21.2) / CSNK1G3 (5q23.2)GABPB1 (15q21.2) / GALK2 (15q21.1)GABPB1 (15q21.2) / PPP1R15B (1q32.1)
GABPB1 (15q21.2) / SPATA5L1 (15q21.1)GABPB1 GALK2GABPB1 SPATA5L1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GABPB1   4074
Cards
Entrez_Gene (NCBI)GABPB1  2553  GA binding protein transcription factor, beta subunit 1
AliasesBABPB2; E4TF1; E4TF1-47; E4TF1-53; 
E4TF1B; GABPB; GABPB2; NRF2B1; NRF2B2
GeneCards (Weizmann)GABPB1
Ensembl hg19 (Hinxton)ENSG00000104064 [Gene_View]  chr15:50578077-50647605 [Contig_View]  GABPB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104064 [Gene_View]  chr15:50578077-50647605 [Contig_View]  GABPB1 [Vega]
ICGC DataPortalENSG00000104064
TCGA cBioPortalGABPB1
AceView (NCBI)GABPB1
Genatlas (Paris)GABPB1
WikiGenes2553
SOURCE (Princeton)GABPB1
Genetics Home Reference (NIH)GABPB1
Genomic and cartography
GoldenPath hg19 (UCSC)GABPB1  -     chr15:50578077-50647605 -  15q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GABPB1  -     15q21.2   [Description]    (hg38-Dec_2013)
EnsemblGABPB1 - 15q21.2 [CytoView hg19]  GABPB1 - 15q21.2 [CytoView hg38]
Mapping of homologs : NCBIGABPB1 [Mapview hg19]  GABPB1 [Mapview hg38]
OMIM600610   
Gene and transcription
Genbank (Entrez)AI631183 AK301350 AK303901 BC016910 BC036080
RefSeq transcript (Entrez)NM_002041 NM_005254 NM_016654 NM_016655 NM_181427
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_029475 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)GABPB1
Cluster EST : UnigeneHs.654350 [ NCBI ]
CGAP (NCI)Hs.654350
Alternative Splicing GalleryENSG00000104064
Gene ExpressionGABPB1 [ NCBI-GEO ]   GABPB1 [ EBI - ARRAY_EXPRESS ]   GABPB1 [ SEEK ]   GABPB1 [ MEM ]
Gene Expression Viewer (FireBrowse)GABPB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2553
GTEX Portal (Tissue expression)GABPB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06547   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06547  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06547
Splice isoforms : SwissVarQ06547
PhosPhoSitePlusQ06547
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)Ank (PF00023)   
Domain families : Pfam (NCBI)pfam00023   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)GABPB1
DMDM Disease mutations2553
Blocks (Seattle)GABPB1
SuperfamilyQ06547
Human Protein AtlasENSG00000104064
Peptide AtlasQ06547
HPRD15975
IPIIPI00031516   IPI00218611   IPI00219016   IPI00010301   IPI01011500   
Protein Interaction databases
DIP (DOE-UCLA)Q06547
IntAct (EBI)Q06547
FunCoupENSG00000104064
BioGRIDGABPB1
STRING (EMBL)GABPB1
ZODIACGABPB1
Ontologies - Pathways
QuickGOQ06547
Ontology : AmiGOsequence-specific DNA binding transcription factor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  organelle organization  mitochondrion organization  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  
Ontology : EGO-EBIsequence-specific DNA binding transcription factor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  organelle organization  mitochondrion organization  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  
NDEx NetworkGABPB1
Atlas of Cancer Signalling NetworkGABPB1
Wikipedia pathwaysGABPB1
Orthology - Evolution
OrthoDB2553
GeneTree (enSembl)ENSG00000104064
Phylogenetic Trees/Animal Genes : TreeFamGABPB1
HOVERGENQ06547
HOGENOMQ06547
Homologs : HomoloGeneGABPB1
Homology/Alignments : Family Browser (UCSC)GABPB1
Gene fusions - Rearrangements
Fusion: TCGAGABPB1 GALK2
Fusion: TCGAGABPB1 SPATA5L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGABPB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GABPB1
dbVarGABPB1
ClinVarGABPB1
1000_GenomesGABPB1 
Exome Variant ServerGABPB1
ExAC (Exome Aggregation Consortium)GABPB1 (select the gene name)
Genetic variants : HAPMAP2553
Genomic Variants (DGV)GABPB1 [DGVbeta]
DECIPHER (Syndromes)15:50578077-50647605  ENSG00000104064
CONAN: Copy Number AnalysisGABPB1 
Mutations
ICGC Data PortalGABPB1 
TCGA Data PortalGABPB1 
Broad Tumor PortalGABPB1
OASIS PortalGABPB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGABPB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGABPB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GABPB1
DgiDB (Drug Gene Interaction Database)GABPB1
DoCM (Curated mutations)GABPB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GABPB1 (select a term)
intoGenGABPB1
Cancer3DGABPB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600610   
Orphanet
MedgenGABPB1
Genetic Testing Registry GABPB1
NextProtQ06547 [Medical]
TSGene2553
GENETestsGABPB1
Huge Navigator GABPB1 [HugePedia]
snp3D : Map Gene to Disease2553
BioCentury BCIQGABPB1
ClinGenGABPB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2553
Chemical/Pharm GKB GenePA162389163
Clinical trialGABPB1
Miscellaneous
canSAR (ICR)GABPB1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGABPB1
EVEXGABPB1
GoPubMedGABPB1
iHOPGABPB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:05:37 CET 2017

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