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GABRA6 (gamma-aminobutyric acid type A receptor alpha6 subunit)

Identity

Alias_namesgamma-aminobutyric acid (GABA) A receptor, alpha 6
Other alias-
HGNC (Hugo) GABRA6
LocusID (NCBI) 2559
Atlas_Id 63650
Location 5q34  [Link to chromosome band 5q34]
Location_base_pair Starts at 161685652 and ends at 161702592 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GABRA6   4080
Cards
Entrez_Gene (NCBI)GABRA6  2559  gamma-aminobutyric acid type A receptor alpha6 subunit
Aliases
GeneCards (Weizmann)GABRA6
Ensembl hg19 (Hinxton)ENSG00000145863 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145863 [Gene_View]  chr5:161685652-161702592 [Contig_View]  GABRA6 [Vega]
ICGC DataPortalENSG00000145863
TCGA cBioPortalGABRA6
AceView (NCBI)GABRA6
Genatlas (Paris)GABRA6
WikiGenes2559
SOURCE (Princeton)GABRA6
Genetics Home Reference (NIH)GABRA6
Genomic and cartography
GoldenPath hg38 (UCSC)GABRA6  -     chr5:161685652-161702592 +  5q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GABRA6  -     5q34   [Description]    (hg19-Feb_2009)
EnsemblGABRA6 - 5q34 [CytoView hg19]  GABRA6 - 5q34 [CytoView hg38]
Mapping of homologs : NCBIGABRA6 [Mapview hg19]  GABRA6 [Mapview hg38]
OMIM137143   
Gene and transcription
Genbank (Entrez)AK090735 AK289461 BC096241 BC096242 BC099640
RefSeq transcript (Entrez)NM_000811
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GABRA6
Cluster EST : UnigeneHs.90791 [ NCBI ]
CGAP (NCI)Hs.90791
Alternative Splicing GalleryENSG00000145863
Gene ExpressionGABRA6 [ NCBI-GEO ]   GABRA6 [ EBI - ARRAY_EXPRESS ]   GABRA6 [ SEEK ]   GABRA6 [ MEM ]
Gene Expression Viewer (FireBrowse)GABRA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2559
GTEX Portal (Tissue expression)GABRA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16445   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16445  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16445
Splice isoforms : SwissVarQ16445
PhosPhoSitePlusQ16445
Domaine pattern : Prosite (Expaxy)NEUROTR_ION_CHANNEL (PS00236)   
Domains : Interpro (EBI)GABAA/Glycine_rcpt    GABAAa_rcpt    GABBAa6_rcpt    Neur_chan_lig-bd    Neur_channel    Neurotrans-gated_channel_TM    Neurotransmitter_ion_chnl_CS   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)GABRA6
DMDM Disease mutations2559
Blocks (Seattle)GABRA6
SuperfamilyQ16445
Human Protein AtlasENSG00000145863
Peptide AtlasQ16445
HPRD08841
IPIIPI00002215   IPI00984249   IPI00977323   IPI00983650   IPI00976777   
Protein Interaction databases
DIP (DOE-UCLA)Q16445
IntAct (EBI)Q16445
FunCoupENSG00000145863
BioGRIDGABRA6
STRING (EMBL)GABRA6
ZODIACGABRA6
Ontologies - Pathways
QuickGOQ16445
Ontology : AmiGOGABA-A receptor activity  extracellular ligand-gated ion channel activity  chloride channel activity  plasma membrane  integral component of plasma membrane  transport  signal transduction  gamma-aminobutyric acid signaling pathway  benzodiazepine receptor activity  cell junction  ion transmembrane transport  chloride channel complex  postsynaptic membrane  chloride transmembrane transport  GABA-A receptor complex  
Ontology : EGO-EBIGABA-A receptor activity  extracellular ligand-gated ion channel activity  chloride channel activity  plasma membrane  integral component of plasma membrane  transport  signal transduction  gamma-aminobutyric acid signaling pathway  benzodiazepine receptor activity  cell junction  ion transmembrane transport  chloride channel complex  postsynaptic membrane  chloride transmembrane transport  GABA-A receptor complex  
Pathways : BIOCARTACardiac Protection Against ROS [Genes]    Gamma-aminobutyric Acid Receptor Life Cycle [Genes]   
Pathways : KEGGNeuroactive ligand-receptor interaction    Retrograde endocannabinoid signaling    GABAergic synapse    Morphine addiction    Nicotine addiction   
NDEx NetworkGABRA6
Atlas of Cancer Signalling NetworkGABRA6
Wikipedia pathwaysGABRA6
Orthology - Evolution
OrthoDB2559
GeneTree (enSembl)ENSG00000145863
Phylogenetic Trees/Animal Genes : TreeFamGABRA6
HOVERGENQ16445
HOGENOMQ16445
Homologs : HomoloGeneGABRA6
Homology/Alignments : Family Browser (UCSC)GABRA6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGABRA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GABRA6
dbVarGABRA6
ClinVarGABRA6
1000_GenomesGABRA6 
Exome Variant ServerGABRA6
ExAC (Exome Aggregation Consortium)GABRA6 (select the gene name)
Genetic variants : HAPMAP2559
Genomic Variants (DGV)GABRA6 [DGVbeta]
DECIPHERGABRA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGABRA6 
Mutations
ICGC Data PortalGABRA6 
TCGA Data PortalGABRA6 
Broad Tumor PortalGABRA6
OASIS PortalGABRA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGABRA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGABRA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GABRA6
DgiDB (Drug Gene Interaction Database)GABRA6
DoCM (Curated mutations)GABRA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GABRA6 (select a term)
intoGenGABRA6
Cancer3DGABRA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137143   
Orphanet
MedgenGABRA6
Genetic Testing Registry GABRA6
NextProtQ16445 [Medical]
TSGene2559
GENETestsGABRA6
Target ValidationGABRA6
Huge Navigator GABRA6 [HugePedia]
snp3D : Map Gene to Disease2559
BioCentury BCIQGABRA6
ClinGenGABRA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2559
Chemical/Pharm GKB GenePA28494
Clinical trialGABRA6
Miscellaneous
canSAR (ICR)GABRA6 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGABRA6
EVEXGABRA6
GoPubMedGABRA6
iHOPGABRA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:50:08 CEST 2017

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