Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55879
MIM: 300349
HGNC: 14454
Ensembl: ENSG00000268089
Variants:
dbSNP: 55879
ClinVar: 55879
TCGA: ENSG00000268089
COSMIC: GABRQ
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000268089 | ENST00000598523 | Q9UN88 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 23394390 | |
| PA451866 | venlafaxine | Chemical | ClinicalAnnotation | associated | PD | 23394390 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35152451 | 2022 | The severity of behavioural symptoms in FTD is linked to the loss of GABRQ-expressing VENs and pyramidal neurons. | 8 |
| 35152451 | 2022 | The severity of behavioural symptoms in FTD is linked to the loss of GABRQ-expressing VENs and pyramidal neurons. | 8 |
| 33772085 | 2021 | A pioneering study indicate role of GABRQ rs3810651 in ASD severity of Indo-Caucasoid female probands. | 1 |
| 33772085 | 2021 | A pioneering study indicate role of GABRQ rs3810651 in ASD severity of Indo-Caucasoid female probands. | 1 |
| 31610743 | 2019 | Anterograde trafficking signals in GABA(A) subunits are required for functional expression. | 0 |
| 31610743 | 2019 | Anterograde trafficking signals in GABA(A) subunits are required for functional expression. | 0 |
| 29299688 | 2018 | Gamma-aminobutyric acid (GABA) receptors GABRA4, GABRE, and GABRQ gene polymorphisms and risk for migraine. | 6 |
| 29299688 | 2018 | Gamma-aminobutyric acid (GABA) receptors GABRA4, GABRE, and GABRQ gene polymorphisms and risk for migraine. | 6 |
| 23169495 | 2013 | Analysis of the effects of rare variants on splicing identifies alterations in GABAA receptor genes in autism spectrum disorder individuals. | 26 |
| 23169495 | 2013 | Analysis of the effects of rare variants on splicing identifies alterations in GABAA receptor genes in autism spectrum disorder individuals. | 26 |
| 22690081 | 2012 | GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit. | 28 |
| 22690081 | 2012 | GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit. | 28 |
| 21422964 | 2011 | Gamma-aminobutyric acid GABRA4, GABRE, and GABRQ receptor polymorphisms and risk for essential tremor. | 11 |
| 21422964 | 2011 | Gamma-aminobutyric acid GABRA4, GABRE, and GABRQ receptor polymorphisms and risk for essential tremor. | 11 |
| 19078961 | 2010 | Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. | 55 |
Citation
Dessen P
GABRQ (gamma-aminobutyric acid type A receptor subunit theta)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52936/gabrq
