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GADD45B (growth arrest and DNA damage inducible beta)

Identity

Alias_namesMYD118
growth arrest and DNA-damage-inducible
Alias_symbol (synonym)GADD45BETA
DKFZP566B133
Other alias
HGNC (Hugo) GADD45B
LocusID (NCBI) 4616
Atlas_Id 40666
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 2476125 and ends at 2478259 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GADD45B   4096
Cards
Entrez_Gene (NCBI)GADD45B  4616  growth arrest and DNA damage inducible beta
AliasesGADD45BETA; MYD118
GeneCards (Weizmann)GADD45B
Ensembl hg19 (Hinxton)ENSG00000099860 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099860 [Gene_View]  chr19:2476125-2478259 [Contig_View]  GADD45B [Vega]
ICGC DataPortalENSG00000099860
TCGA cBioPortalGADD45B
AceView (NCBI)GADD45B
Genatlas (Paris)GADD45B
WikiGenes4616
SOURCE (Princeton)GADD45B
Genetics Home Reference (NIH)GADD45B
Genomic and cartography
GoldenPath hg38 (UCSC)GADD45B  -     chr19:2476125-2478259 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GADD45B  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblGADD45B - 19p13.3 [CytoView hg19]  GADD45B - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIGADD45B [Mapview hg19]  GADD45B [Mapview hg38]
OMIM604948   
Gene and transcription
Genbank (Entrez)AF078077 AF087853 AF090950 AK129595 AK293087
RefSeq transcript (Entrez)NM_015675
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GADD45B
Cluster EST : UnigeneHs.110571 [ NCBI ]
CGAP (NCI)Hs.110571
Alternative Splicing GalleryENSG00000099860
Gene ExpressionGADD45B [ NCBI-GEO ]   GADD45B [ EBI - ARRAY_EXPRESS ]   GADD45B [ SEEK ]   GADD45B [ MEM ]
Gene Expression Viewer (FireBrowse)GADD45B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4616
GTEX Portal (Tissue expression)GADD45B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75293   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75293  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75293
Splice isoforms : SwissVarO75293
PhosPhoSitePlusO75293
Domains : Interpro (EBI)GADD45    L30e-like    Ribosomal_L7Ae/L30e/S12e/Gad45   
Domain families : Pfam (Sanger)Ribosomal_L7Ae (PF01248)   
Domain families : Pfam (NCBI)pfam01248   
Conserved Domain (NCBI)GADD45B
DMDM Disease mutations4616
Blocks (Seattle)GADD45B
SuperfamilyO75293
Human Protein AtlasENSG00000099860
Peptide AtlasO75293
HPRD05382
IPIIPI00307805   IPI00977218   
Protein Interaction databases
DIP (DOE-UCLA)O75293
IntAct (EBI)O75293
FunCoupENSG00000099860
BioGRIDGADD45B
STRING (EMBL)GADD45B
ZODIACGADD45B
Ontologies - Pathways
QuickGOO75293
Ontology : AmiGOactivation of MAPKKK activity  activation of MAPKK activity  protein binding  nucleus  cytoplasm  negative regulation of protein kinase activity  apoptotic process  response to stress  multicellular organism development  cell differentiation  positive regulation of apoptotic process  positive regulation of JNK cascade  regulation of cell cycle  positive regulation of p38MAPK cascade  
Ontology : EGO-EBIactivation of MAPKKK activity  activation of MAPKK activity  protein binding  nucleus  cytoplasm  negative regulation of protein kinase activity  apoptotic process  response to stress  multicellular organism development  cell differentiation  positive regulation of apoptotic process  positive regulation of JNK cascade  regulation of cell cycle  positive regulation of p38MAPK cascade  
Pathways : KEGGMAPK signaling pathway    NF-kappa B signaling pathway    FoxO signaling pathway    Cell cycle    p53 signaling pathway   
NDEx NetworkGADD45B
Atlas of Cancer Signalling NetworkGADD45B
Wikipedia pathwaysGADD45B
Orthology - Evolution
OrthoDB4616
GeneTree (enSembl)ENSG00000099860
Phylogenetic Trees/Animal Genes : TreeFamGADD45B
HOVERGENO75293
HOGENOMO75293
Homologs : HomoloGeneGADD45B
Homology/Alignments : Family Browser (UCSC)GADD45B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGADD45B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GADD45B
dbVarGADD45B
ClinVarGADD45B
1000_GenomesGADD45B 
Exome Variant ServerGADD45B
ExAC (Exome Aggregation Consortium)GADD45B (select the gene name)
Genetic variants : HAPMAP4616
Genomic Variants (DGV)GADD45B [DGVbeta]
DECIPHERGADD45B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGADD45B 
Mutations
ICGC Data PortalGADD45B 
TCGA Data PortalGADD45B 
Broad Tumor PortalGADD45B
OASIS PortalGADD45B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGADD45B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGADD45B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GADD45B
DgiDB (Drug Gene Interaction Database)GADD45B
DoCM (Curated mutations)GADD45B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GADD45B (select a term)
intoGenGADD45B
Cancer3DGADD45B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604948   
Orphanet
MedgenGADD45B
Genetic Testing Registry GADD45B
NextProtO75293 [Medical]
TSGene4616
GENETestsGADD45B
Target ValidationGADD45B
Huge Navigator GADD45B [HugePedia]
snp3D : Map Gene to Disease4616
BioCentury BCIQGADD45B
ClinGenGADD45B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4616
Chemical/Pharm GKB GenePA28511
Clinical trialGADD45B
Miscellaneous
canSAR (ICR)GADD45B (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGADD45B
EVEXGADD45B
GoPubMedGADD45B
iHOPGADD45B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:09:19 CEST 2017

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