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GADD45G (growth arrest and DNA damage inducible gamma)

Identity

Alias_namesgrowth arrest and DNA-damage-inducible
Alias_symbol (synonym)DDIT2
GADD45gamma
GRP17
CR6
Other alias
HGNC (Hugo) GADD45G
LocusID (NCBI) 10912
Atlas_Id 40667
Location 9q22.2  [Link to chromosome band 9q22]
Location_base_pair Starts at 92219927 and ends at 92221469 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GADD45G (9q22.2) / CYP11B1 (8q24.3)GADD45G (9q22.2) / WARS (14q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GADD45G   4097
Cards
Entrez_Gene (NCBI)GADD45G  10912  growth arrest and DNA damage inducible gamma
AliasesCR6; DDIT2; GADD45gamma; GRP17
GeneCards (Weizmann)GADD45G
Ensembl hg19 (Hinxton)ENSG00000130222 [Gene_View]  chr9:92219927-92221469 [Contig_View]  GADD45G [Vega]
Ensembl hg38 (Hinxton)ENSG00000130222 [Gene_View]  chr9:92219927-92221469 [Contig_View]  GADD45G [Vega]
ICGC DataPortalENSG00000130222
TCGA cBioPortalGADD45G
AceView (NCBI)GADD45G
Genatlas (Paris)GADD45G
WikiGenes10912
SOURCE (Princeton)GADD45G
Genetics Home Reference (NIH)GADD45G
Genomic and cartography
GoldenPath hg19 (UCSC)GADD45G  -     chr9:92219927-92221469 +  9q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GADD45G  -     9q22.2   [Description]    (hg38-Dec_2013)
EnsemblGADD45G - 9q22.2 [CytoView hg19]  GADD45G - 9q22.2 [CytoView hg38]
Mapping of homologs : NCBIGADD45G [Mapview hg19]  GADD45G [Mapview hg38]
OMIM604949   
Gene and transcription
Genbank (Entrez)AF078078 AF079806 AF087883 AK313689 AY845250
RefSeq transcript (Entrez)NM_006705
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)GADD45G
Cluster EST : UnigeneHs.9701 [ NCBI ]
CGAP (NCI)Hs.9701
Alternative Splicing GalleryENSG00000130222
Gene ExpressionGADD45G [ NCBI-GEO ]   GADD45G [ EBI - ARRAY_EXPRESS ]   GADD45G [ SEEK ]   GADD45G [ MEM ]
Gene Expression Viewer (FireBrowse)GADD45G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10912
GTEX Portal (Tissue expression)GADD45G
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95257   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95257  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95257
Splice isoforms : SwissVarO95257
PhosPhoSitePlusO95257
Domains : Interpro (EBI)GADD45    L30e-like    Ribosomal_L7Ae/L30e/S12e/Gad45   
Domain families : Pfam (Sanger)Ribosomal_L7Ae (PF01248)   
Domain families : Pfam (NCBI)pfam01248   
Conserved Domain (NCBI)GADD45G
DMDM Disease mutations10912
Blocks (Seattle)GADD45G
PDB (SRS)2WAL    3FFM   
PDB (PDBSum)2WAL    3FFM   
PDB (IMB)2WAL    3FFM   
PDB (RSDB)2WAL    3FFM   
Structural Biology KnowledgeBase2WAL    3FFM   
SCOP (Structural Classification of Proteins)2WAL    3FFM   
CATH (Classification of proteins structures)2WAL    3FFM   
SuperfamilyO95257
Human Protein AtlasENSG00000130222
Peptide AtlasO95257
HPRD05383
IPIIPI00029458   IPI00642646   
Protein Interaction databases
DIP (DOE-UCLA)O95257
IntAct (EBI)O95257
FunCoupENSG00000130222
BioGRIDGADD45G
STRING (EMBL)GADD45G
ZODIACGADD45G
Ontologies - Pathways
QuickGOO95257
Ontology : AmiGOactivation of MAPKKK activity  protein binding  nucleus  cytoplasm  apoptotic process  response to stress  multicellular organism development  cell differentiation  positive regulation of apoptotic process  positive regulation of JNK cascade  regulation of cell cycle  positive regulation of p38MAPK cascade  
Ontology : EGO-EBIactivation of MAPKKK activity  protein binding  nucleus  cytoplasm  apoptotic process  response to stress  multicellular organism development  cell differentiation  positive regulation of apoptotic process  positive regulation of JNK cascade  regulation of cell cycle  positive regulation of p38MAPK cascade  
Pathways : KEGGMAPK signaling pathway    FoxO signaling pathway    Cell cycle    p53 signaling pathway   
NDEx NetworkGADD45G
Atlas of Cancer Signalling NetworkGADD45G
Wikipedia pathwaysGADD45G
Orthology - Evolution
OrthoDB10912
GeneTree (enSembl)ENSG00000130222
Phylogenetic Trees/Animal Genes : TreeFamGADD45G
HOVERGENO95257
HOGENOMO95257
Homologs : HomoloGeneGADD45G
Homology/Alignments : Family Browser (UCSC)GADD45G
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGADD45G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GADD45G
dbVarGADD45G
ClinVarGADD45G
1000_GenomesGADD45G 
Exome Variant ServerGADD45G
ExAC (Exome Aggregation Consortium)GADD45G (select the gene name)
Genetic variants : HAPMAP10912
Genomic Variants (DGV)GADD45G [DGVbeta]
DECIPHER (Syndromes)9:92219927-92221469  ENSG00000130222
CONAN: Copy Number AnalysisGADD45G 
Mutations
ICGC Data PortalGADD45G 
TCGA Data PortalGADD45G 
Broad Tumor PortalGADD45G
OASIS PortalGADD45G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGADD45G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGADD45G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GADD45G
DgiDB (Drug Gene Interaction Database)GADD45G
DoCM (Curated mutations)GADD45G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GADD45G (select a term)
intoGenGADD45G
Cancer3DGADD45G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604949   
Orphanet
MedgenGADD45G
Genetic Testing Registry GADD45G
NextProtO95257 [Medical]
TSGene10912
GENETestsGADD45G
Huge Navigator GADD45G [HugePedia]
snp3D : Map Gene to Disease10912
BioCentury BCIQGADD45G
ClinGenGADD45G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10912
Chemical/Pharm GKB GenePA28512
Clinical trialGADD45G
Miscellaneous
canSAR (ICR)GADD45G (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGADD45G
EVEXGADD45G
GoPubMedGADD45G
iHOPGADD45G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:01:57 CEST 2017

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