Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GAK (cyclin G associated kinase)

Identity

Other namesDNAJ26
DNAJC26
HGNC (Hugo) GAK
LocusID (NCBI) 2580
Location 4p16.3
Location_base_pair Starts at 843066 and ends at 926178 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GAK   4113
Cards
Entrez_Gene (NCBI)GAK  2580  cyclin G associated kinase
GeneCards (Weizmann)GAK
Ensembl (Hinxton)ENSG00000178950 [Gene_View]  chr4:843066-926178 [Contig_View]  GAK [Vega]
ICGC DataPortalENSG00000178950
cBioPortalGAK
AceView (NCBI)GAK
Genatlas (Paris)GAK
WikiGenes2580
SOURCE (Princeton)NM_001286833 NM_005255
Genomic and cartography
GoldenPath (UCSC)GAK  -  4p16.3   chr4:843066-926178 -  4p16.3   [Description]    (hg19-Feb_2009)
EnsemblGAK - 4p16.3 [CytoView]
Mapping of homologs : NCBIGAK [Mapview]
OMIM602052   
Gene and transcription
Genbank (Entrez)AB208854 AK097714 AK126735 AK127351 AK131464
RefSeq transcript (Entrez)NM_001286833 NM_005255
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_006051 NW_001838895 NW_004929313
Consensus coding sequences : CCDS (NCBI)GAK
Cluster EST : UnigeneHs.369607 [ NCBI ]
CGAP (NCI)Hs.369607
Alternative Splicing : Fast-db (Paris)GSHG0023057
Alternative Splicing GalleryENSG00000178950
Gene ExpressionGAK [ NCBI-GEO ]     GAK [ SEEK ]   GAK [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14976 (Uniprot)
NextProtO14976  [Medical]
With graphics : InterProO14976
Splice isoforms : SwissVarO14976 (Swissvar)
Domaine pattern : Prosite (Expaxy)C2_TENSIN (PS51182)    DNAJ_2 (PS50076)    PPASE_TENSIN (PS51181)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)C2_dom [organisation]   DnaJ_domain [organisation]   Kinase-like_dom [organisation]   Prot-tyrosine_phosphatase-like [organisation]   Prot_kinase_dom [organisation]   Ser/Thr_kinase_AS [organisation]   Tensin_C2-dom [organisation]   Tensin_lipid_phosphatase_dom [organisation]  
Related proteins : CluSTrO14976
Domain families : Pfam (Sanger)DnaJ (PF00226)    Pkinase (PF00069)    PTEN_C2 (PF10409)   
Domain families : Pfam (NCBI)pfam00226    pfam00069    pfam10409   
Domain families : Smart (EMBL)DnaJ (SM00271)  
DMDM Disease mutations2580
Blocks (Seattle)O14976
PDB (SRS)4C57    4C58    4C59    4O38   
PDB (PDBSum)4C57    4C58    4C59    4O38   
PDB (IMB)4C57    4C58    4C59    4O38   
PDB (RSDB)4C57    4C58    4C59    4O38   
Human Protein AtlasENSG00000178950 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO14976
HPRD03631
IPIIPI00298949   IPI00784139   IPI00442170   IPI00444993   IPI00384168   IPI00965736   IPI00968171   IPI00966048   IPI00964028   IPI00966579   IPI00964549   IPI00967338   IPI00964882   
Protein Interaction databases
DIP (DOE-UCLA)O14976
IntAct (EBI)O14976
FunCoupENSG00000178950
BioGRIDGAK
InParanoidO14976
Interologous Interaction database O14976
IntegromeDBGAK
STRING (EMBL)GAK
Ontologies - Pathways
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  Golgi apparatus  focal adhesion  protein phosphorylation  cell cycle  membrane  intracellular membrane-bounded organelle  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  Golgi apparatus  focal adhesion  protein phosphorylation  cell cycle  membrane  intracellular membrane-bounded organelle  perinuclear region of cytoplasm  
Protein Interaction DatabaseGAK
Wikipedia pathwaysGAK
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GAK
snp3D : Map Gene to Disease2580
SNP (GeneSNP Utah)GAK
SNP : HGBaseGAK
Genetic variants : HAPMAPGAK
Exome VariantGAK
1000_GenomesGAK 
ICGC programENSG00000178950 
Somatic Mutations in Cancer : COSMICGAK 
CONAN: Copy Number AnalysisGAK 
Mutations and Diseases : HGMDGAK
Genomic VariantsGAK  GAK [DGVbeta]
dbVarGAK
ClinVarGAK
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602052   
MedgenGAK
GENETestsGAK
Disease Genetic AssociationGAK
Huge Navigator GAK [HugePedia]  GAK [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGAK
Homology/Alignments : Family Browser (UCSC)GAK
Phylogenetic Trees/Animal Genes : TreeFamGAK
Chemical/Protein Interactions : CTD2580
Chemical/Pharm GKB GenePA28528
Clinical trialGAK
Cancer Resource (Charite)ENSG00000178950
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineGAK
iHOPGAK
OncoSearchGAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:32:29 CEST 2014
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