Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GAK (cyclin G associated kinase)

Identity

Other namesDNAJ26
DNAJC26
HGNC (Hugo) GAK
LocusID (NCBI) 2580
Location 4p16.3
Location_base_pair Starts at 843066 and ends at 926178 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GAK   4113
Cards
Entrez_Gene (NCBI)GAK  2580  cyclin G associated kinase
GeneCards (Weizmann)GAK
Ensembl hg19 (Hinxton)ENSG00000178950 [Gene_View]  chr4:843066-926178 [Contig_View]  GAK [Vega]
Ensembl hg38 (Hinxton)ENSG00000178950 [Gene_View]  chr4:843066-926178 [Contig_View]  GAK [Vega]
ICGC DataPortalENSG00000178950
cBioPortalGAK
AceView (NCBI)GAK
Genatlas (Paris)GAK
WikiGenes2580
SOURCE (Princeton)GAK
Genomic and cartography
GoldenPath hg19 (UCSC)GAK  -     chr4:843066-926178 -  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GAK  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblGAK - 4p16.3 [CytoView hg19]  GAK - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIGAK [Mapview hg19]  GAK [Mapview hg38]
OMIM602052   
Gene and transcription
Genbank (Entrez)AB208854 AK097714 AK126735 AK127351 AK131464
RefSeq transcript (Entrez)NM_001286833 NM_005255
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_006051 NW_001838895 NW_004929313
Consensus coding sequences : CCDS (NCBI)GAK
Cluster EST : UnigeneHs.369607 [ NCBI ]
CGAP (NCI)Hs.369607
Alternative Splicing : Fast-db (Paris)GSHG0023057
Alternative Splicing GalleryENSG00000178950
Gene ExpressionGAK [ NCBI-GEO ]     GAK [ SEEK ]   GAK [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14976 (Uniprot)
NextProtO14976  [Medical]
With graphics : InterProO14976
Splice isoforms : SwissVarO14976 (Swissvar)
Domaine pattern : Prosite (Expaxy)C2_TENSIN (PS51182)    DNAJ_2 (PS50076)    PPASE_TENSIN (PS51181)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)C2_dom    DnaJ_domain    Kinase-like_dom    Prot-tyrosine_phosphatase-like    Prot_kinase_dom    Ser/Thr_kinase_AS    Tensin_C2-dom    Tensin_lipid_phosphatase_dom   
Related proteins : CluSTrO14976
Domain families : Pfam (Sanger)DnaJ (PF00226)    Pkinase (PF00069)    PTEN_C2 (PF10409)   
Domain families : Pfam (NCBI)pfam00226    pfam00069    pfam10409   
Domain families : Smart (EMBL)DnaJ (SM00271)  
DMDM Disease mutations2580
Blocks (Seattle)O14976
PDB (SRS)4C57    4C58    4C59    4O38   
PDB (PDBSum)4C57    4C58    4C59    4O38   
PDB (IMB)4C57    4C58    4C59    4O38   
PDB (RSDB)4C57    4C58    4C59    4O38   
Human Protein AtlasENSG00000178950
Peptide AtlasO14976
HPRD03631
IPIIPI00298949   IPI00784139   IPI00442170   IPI00444993   IPI00384168   IPI00965736   IPI00968171   IPI00966048   IPI00964028   IPI00966579   IPI00964549   IPI00967338   IPI00964882   
Protein Interaction databases
DIP (DOE-UCLA)O14976
IntAct (EBI)O14976
FunCoupENSG00000178950
BioGRIDGAK
IntegromeDBGAK
STRING (EMBL)GAK
Ontologies - Pathways
QuickGOO14976
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  Golgi apparatus  focal adhesion  protein phosphorylation  cell cycle  membrane  intracellular membrane-bounded organelle  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  Golgi apparatus  focal adhesion  protein phosphorylation  cell cycle  membrane  intracellular membrane-bounded organelle  perinuclear region of cytoplasm  
Protein Interaction DatabaseGAK
DoCM (Curated mutations)GAK
Wikipedia pathwaysGAK
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGAK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GAK
dbVarGAK
ClinVarGAK
1000_GenomesGAK 
Exome Variant ServerGAK
SNP (GeneSNP Utah)GAK
SNP : HGBaseGAK
Genetic variants : HAPMAPGAK
Genomic VariantsGAK  GAK [DGVbeta]
Mutations
ICGC Data PortalENSG00000178950 
Somatic Mutations in Cancer : COSMICGAK 
CONAN: Copy Number AnalysisGAK 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:843066-926178
Mutations and Diseases : HGMDGAK
OMIM602052   
MedgenGAK
NextProtO14976 [Medical]
GENETestsGAK
Disease Genetic AssociationGAK
Huge Navigator GAK [HugePedia]  GAK [HugeCancerGEM]
snp3D : Map Gene to Disease2580
DGIdb (Drug Gene Interaction db)GAK
General knowledge
Homologs : HomoloGeneGAK
Homology/Alignments : Family Browser (UCSC)GAK
Phylogenetic Trees/Animal Genes : TreeFamGAK
Chemical/Protein Interactions : CTD2580
Chemical/Pharm GKB GenePA28528
Clinical trialGAK
Cancer Resource (Charite)ENSG00000178950
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineGAK
GoPubMedGAK
iHOPGAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 21:43:10 CET 2014
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