Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GAK (cyclin G associated kinase)

Identity

Other namesDNAJ26
DNAJC26
HGNC (Hugo) GAK
LocusID (NCBI) 2580
Location 4p16.3
Location_base_pair Starts at 843065 and ends at 926174 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GAK   4113
Entrez_Gene (NCBI)GAK  2580  cyclin G associated kinase
Cards
GeneCards (Weizmann)GAK
Ensembl (Hinxton)ENSG00000178950 [Gene_View]  chr4:843065-926174 [Contig_View]  GAK [Vega]
AceView (NCBI)GAK
Genatlas (Paris)GAK
SOURCE (Stanford)NM_001286833 NM_005255
Genomic and cartography
GoldenPath (UCSC)GAK  -  4p16.3   chr4:843065-926174 -  4p16.3   [Description]    (hg19-Feb_2009)
EnsemblGAK - 4p16.3 [CytoView]
Mapping of homologs : NCBIGAK [Mapview]
OMIM602052   
Gene and transcription
Genbank (Entrez)AB208854 AK097714 AK126735 AK127351 AK131464
RefSeq transcript (SRS)NM_001286833 NM_005255
RefSeq transcript (Entrez)NM_001286833 NM_005255
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_037622 NW_001838895 NW_004929313
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_037622 NW_001838895 NW_004929313
Consensus coding sequences : CCDS (NCBI)GAK
Cluster EST : UnigeneHs.369607 [ SRS ] Hs.369607 [ NCBI ]
CGAP (NCI)Hs.369607
Alternative Splicing : Fast-db (Paris)GSHG0023057
Alternative Splicing GalleryENSG00000178950
Gene ExpressionGAK [ NCBI-GEO ]   GAK [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14976 (SRS) O14976 (Uniprot)
NextProtO14976  [Medical]
With graphics : InterProO14976
Splice isoforms : SwissVarO14976(Swissvar)
Domaine pattern : Prosite (SRS)C2_TENSIN (PS51182)    DNAJ_1 (PS00636)    DNAJ_2 (PS50076)    PPASE_TENSIN (PS51181)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)C2_TENSIN (PS51182)    DNAJ_1 (PS00636)    DNAJ_2 (PS50076)    PPASE_TENSIN (PS51181)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)C2_dom    DnaJ_domain    Kinase-like_dom    Phosphatase_tensin-typ    Prot_kinase_dom    Ser/Thr_kinase_AS    Tensin_phosphatase_C2-dom   
Domains : Interpro (EBI)C2_dom    DnaJ_domain    Kinase-like_dom    Phosphatase_tensin-typ    Prot_kinase_dom    Ser/Thr_kinase_AS    Tensin_phosphatase_C2-dom   
Related proteins : CluSTrO14976
Domain families : Pfam (SRS)DnaJ (PF00226)    Pkinase (PF00069)    PTEN_C2 (PF10409)   
Domain families : Pfam (Sanger)DnaJ (PF00226)    Pkinase (PF00069)    PTEN_C2 (PF10409)   
Domain families : Pfam (NCBI)pfam00226    pfam00069    pfam10409   
Domain families : Smart (EMBL)DnaJ (SM00271)  
DMDM2580
Blocks (Seattle)O14976
PDB (SRS)3LL6   
PDB (PDBSum)3LL6   
PDB (IMB)3LL6   
PDB (RSDB)3LL6   
Human Protein AtlasENSG00000178950
HPRD03631
IPIIPI00298949   IPI00784139   IPI00442170   IPI00444993   IPI00384168   IPI00965736   IPI00968171   IPI00966048   IPI00964028   IPI00966579   IPI00964549   IPI00967338   IPI00964882   
Protein Interaction databases
DIP (DOE-UCLA)O14976
IntAct (EBI)O14976
FunCoupENSG00000178950
REACTOMEGAK
Protein Interaction Database2580
BioGRIDGAK
InParanoidO14976
Interologous Interaction database O14976
IntegromeDBGAK
Gene fusion - rearrangments
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GAK
SNP (GeneSNP Utah)GAK
SNP : HGBaseGAK
Genetic variants : HAPMAPGAK
Somatic Mutations in Cancer : COSMICGAK 
CONAN: Copy Number AnalysisGAK 
Mutations and Diseases : HGMDGAK
OMIM602052   
GENETests602052   
Disease Genetic AssociationGAK
Huge Navigator GAK [HugePedia]  GAK [HugeCancerGEM]
Genomic VariantsGAK  GAK [DGVbeta]
ClinVarGAK
snp3D : Map Gene to Disease2580
General knowledge
Homologs : HomoloGeneGAK
Homology/Alignments : Family Browser (UCSC)GAK
Phylogenetic Trees/Animal Genes : TreeFamGAK
Chemical/Protein Interactions : CTD2580
Chemical/Pharm GKB GenePA28528
Clinical trialGAK
Cancer Resource (Charite)ENSG00000178950
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  Golgi apparatus  focal adhesion  cell cycle  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  Golgi apparatus  focal adhesion  cell cycle  perinuclear region of cytoplasm  
Other databases
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
PubGeneGAK
iHOPGAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Dec 3 20:05:19 CET 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.