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GAL (galanin and GMAP prepropeptide)

Identity

Alias_namesGALN
galanin
Alias_symbol (synonym)GMAP
GAL-GMAP
GLNN
Other aliasETL8
HGNC (Hugo) GAL
LocusID (NCBI) 51083
Atlas_Id 45909
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 68684475 and ends at 68691175 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GAB2 (11q14.1) / GAL (11q13.3)GAL (11q13.3) / TEK (9p21.2)LRP5 (11q13.2) / GAL (11q13.3)
OSBP (11q12.1) / GAL (11q13.3)OSBP 11q12.1 / GAL 11q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GAL   4114
Cards
Entrez_Gene (NCBI)GAL  51083  galanin and GMAP prepropeptide
AliasesETL8; GAL-GMAP; GALN; GLNN; 
GMAP
GeneCards (Weizmann)GAL
Ensembl hg19 (Hinxton)ENSG00000069482 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000069482 [Gene_View]  chr11:68684475-68691175 [Contig_View]  GAL [Vega]
ICGC DataPortalENSG00000069482
TCGA cBioPortalGAL
AceView (NCBI)GAL
Genatlas (Paris)GAL
WikiGenes51083
SOURCE (Princeton)GAL
Genetics Home Reference (NIH)GAL
Genomic and cartography
GoldenPath hg38 (UCSC)GAL  -     chr11:68684475-68691175 +  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GAL  -     11q13.2   [Description]    (hg19-Feb_2009)
EnsemblGAL - 11q13.2 [CytoView hg19]  GAL - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIGAL [Mapview hg19]  GAL [Mapview hg38]
OMIM137035   616461   
Gene and transcription
Genbank (Entrez)AF077047 BC030241 BM846531 M77140
RefSeq transcript (Entrez)NM_015973
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GAL
Cluster EST : UnigeneHs.278959 [ NCBI ]
CGAP (NCI)Hs.278959
Alternative Splicing GalleryENSG00000069482
Gene ExpressionGAL [ NCBI-GEO ]   GAL [ EBI - ARRAY_EXPRESS ]   GAL [ SEEK ]   GAL [ MEM ]
Gene Expression Viewer (FireBrowse)GAL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51083
GTEX Portal (Tissue expression)GAL
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22466   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22466  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22466
Splice isoforms : SwissVarP22466
PhosPhoSitePlusP22466
Domaine pattern : Prosite (Expaxy)GALANIN (PS00861)   
Domains : Interpro (EBI)Galanin    Galanin_pre    GMAP   
Domain families : Pfam (Sanger)Galanin (PF01296)    GMAP (PF06540)   
Domain families : Pfam (NCBI)pfam01296    pfam06540   
Domain families : Smart (EMBL)Galanin (SM00071)  
Domain structure : Prodom (Prabi Lyon)Galanin (PD005962)    (PD012185)   
Conserved Domain (NCBI)GAL
DMDM Disease mutations51083
Blocks (Seattle)GAL
SuperfamilyP22466
Human Protein AtlasENSG00000069482
Peptide AtlasP22466
HPRD00658
IPIIPI00026637   IPI00082837   
Protein Interaction databases
DIP (DOE-UCLA)P22466
IntAct (EBI)P22466
FunCoupENSG00000069482
BioGRIDGAL
STRING (EMBL)GAL
ZODIACGAL
Ontologies - Pathways
QuickGOP22466
Ontology : AmiGOgalanin receptor activity  neuropeptide hormone activity  neuropeptide hormone activity  protein binding  extracellular region  extracellular space  Golgi apparatus  inflammatory response  neuropeptide signaling pathway  nervous system development  feeding behavior  protein kinase A signaling  cAMP-mediated signaling  insulin secretion  secretory granule  type 1 galanin receptor binding  type 2 galanin receptor binding  type 3 galanin receptor binding  regulation of glucocorticoid metabolic process  response to insulin  response to immobilization stress  response to drug  neuronal cell body  positive regulation of apoptotic process  response to estrogen  positive regulation of transcription from RNA polymerase II promoter  negative regulation of lymphocyte proliferation  positive regulation of cortisol secretion  positive regulation of timing of catagen  positive regulation of large conductance calcium-activated potassium channel activity  negative regulation of root hair elongation  
Ontology : EGO-EBIgalanin receptor activity  neuropeptide hormone activity  neuropeptide hormone activity  protein binding  extracellular region  extracellular space  Golgi apparatus  inflammatory response  neuropeptide signaling pathway  nervous system development  feeding behavior  protein kinase A signaling  cAMP-mediated signaling  insulin secretion  secretory granule  type 1 galanin receptor binding  type 2 galanin receptor binding  type 3 galanin receptor binding  regulation of glucocorticoid metabolic process  response to insulin  response to immobilization stress  response to drug  neuronal cell body  positive regulation of apoptotic process  response to estrogen  positive regulation of transcription from RNA polymerase II promoter  negative regulation of lymphocyte proliferation  positive regulation of cortisol secretion  positive regulation of timing of catagen  positive regulation of large conductance calcium-activated potassium channel activity  negative regulation of root hair elongation  
NDEx NetworkGAL
Atlas of Cancer Signalling NetworkGAL
Wikipedia pathwaysGAL
Orthology - Evolution
OrthoDB51083
GeneTree (enSembl)ENSG00000069482
Phylogenetic Trees/Animal Genes : TreeFamGAL
HOVERGENP22466
HOGENOMP22466
Homologs : HomoloGeneGAL
Homology/Alignments : Family Browser (UCSC)GAL
Gene fusions - Rearrangements
Fusion : MitelmanOSBP/GAL [11q12.1/11q13.3]  [t(11;11)(q12;q13)]  
Fusion: TCGAOSBP 11q12.1 GAL 11q13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGAL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GAL
dbVarGAL
ClinVarGAL
1000_GenomesGAL 
Exome Variant ServerGAL
ExAC (Exome Aggregation Consortium)GAL (select the gene name)
Genetic variants : HAPMAP51083
Genomic Variants (DGV)GAL [DGVbeta]
DECIPHERGAL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGAL 
Mutations
ICGC Data PortalGAL 
TCGA Data PortalGAL 
Broad Tumor PortalGAL
OASIS PortalGAL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGAL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGAL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GAL
DgiDB (Drug Gene Interaction Database)GAL
DoCM (Curated mutations)GAL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GAL (select a term)
intoGenGAL
Cancer3DGAL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137035    616461   
Orphanet
MedgenGAL
Genetic Testing Registry GAL
NextProtP22466 [Medical]
TSGene51083
GENETestsGAL
Target ValidationGAL
Huge Navigator GAL [HugePedia]
snp3D : Map Gene to Disease51083
BioCentury BCIQGAL
ClinGenGAL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51083
Chemical/Pharm GKB GenePA28529
Clinical trialGAL
Miscellaneous
canSAR (ICR)GAL (select the gene name)
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGAL
EVEXGAL
GoPubMedGAL
iHOPGAL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:09:21 CEST 2017

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