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GALE (UDP-galactose-4-epimerase)

Identity

Other namesSDR1E1
HGNC (Hugo) GALE
LocusID (NCBI) 2582
Location 1p36.11
Location_base_pair Starts at 24122089 and ends at 24127034 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GALE   4116
Cards
Entrez_Gene (NCBI)GALE  2582  UDP-galactose-4-epimerase
GeneCards (Weizmann)GALE
Ensembl (Hinxton)ENSG00000117308 [Gene_View]  chr1:24122089-24127034 [Contig_View]  GALE [Vega]
ICGC DataPortalENSG00000117308
cBioPortalGALE
AceView (NCBI)GALE
Genatlas (Paris)GALE
WikiGenes2582
SOURCE (Princeton)NM_000403 NM_001008216 NM_001127621
Genomic and cartography
GoldenPath (UCSC)GALE  -  1p36.11   chr1:24122089-24127034 -  1p36.11   [Description]    (hg19-Feb_2009)
EnsemblGALE - 1p36.11 [CytoView]
Mapping of homologs : NCBIGALE [Mapview]
OMIM230350   606953   
Gene and transcription
Genbank (Entrez)AK057302 AK096127 AK307354 AK314397 AL530475
RefSeq transcript (Entrez)NM_000403 NM_001008216 NM_001127621
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_007068 NT_032977 NW_001838573 NW_004929289
Consensus coding sequences : CCDS (NCBI)GALE
Cluster EST : UnigeneHs.632380 [ NCBI ]
CGAP (NCI)Hs.632380
Alternative Splicing : Fast-db (Paris)GSHG0001855
Alternative Splicing GalleryENSG00000117308
Gene ExpressionGALE [ NCBI-GEO ]     GALE [ SEEK ]   GALE [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14376 (Uniprot)
NextProtQ14376  [Medical]
With graphics : InterProQ14376
Splice isoforms : SwissVarQ14376 (Swissvar)
Catalytic activity : Enzyme5.1.3.2 [ Enzyme-Expasy ]   5.1.3.25.1.3.2 [ IntEnz-EBI ]   5.1.3.2 [ BRENDA ]   5.1.3.2 [ KEGG ]   
Domains : Interpro (EBI)Epimerase_C [organisation]   Epimerase_deHydtase [organisation]   GalE [organisation]   NAD(P)-bd_dom [organisation]   Nuc_sugar_epim [organisation]  
Related proteins : CluSTrQ14376
Domain families : Pfam (Sanger)Epimerase (PF01370)    Epimerase_Csub (PF13950)   
Domain families : Pfam (NCBI)pfam01370    pfam13950   
DMDM Disease mutations2582
Blocks (Seattle)Q14376
PDB (SRS)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB (PDBSum)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB (IMB)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB (RSDB)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
Human Protein AtlasENSG00000117308 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ14376
HPRD06092
IPIIPI00553131   IPI00030229   IPI00644364   IPI00644339   IPI00641123   IPI00515014   
Protein Interaction databases
DIP (DOE-UCLA)Q14376
IntAct (EBI)Q14376
FunCoupENSG00000117308
BioGRIDGALE
InParanoidQ14376
Interologous Interaction database Q14376
IntegromeDBGALE
STRING (EMBL)GALE
Ontologies - Pathways
Ontology : AmiGOUDP-glucose 4-epimerase activity  UDP-glucose 4-epimerase activity  cytosol  carbohydrate metabolic process  galactose catabolic process  galactose catabolic process  protein homodimerization activity  cellular metabolic process  small molecule metabolic process  coenzyme binding  extracellular vesicular exosome  
Ontology : EGO-EBIUDP-glucose 4-epimerase activity  UDP-glucose 4-epimerase activity  cytosol  carbohydrate metabolic process  galactose catabolic process  galactose catabolic process  protein homodimerization activity  cellular metabolic process  small molecule metabolic process  coenzyme binding  extracellular vesicular exosome  
Pathways : BIOCARTALeloir pathway of galactose metabolism [Genes]   
Pathways : KEGGGalactose metabolism    Amino sugar and nucleotide sugar metabolism   
Protein Interaction DatabaseGALE
Wikipedia pathwaysGALE
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GALE
snp3D : Map Gene to Disease2582
SNP (GeneSNP Utah)GALE
SNP : HGBaseGALE
Genetic variants : HAPMAPGALE
Exome VariantGALE
1000_GenomesGALE 
ICGC programENSG00000117308 
Somatic Mutations in Cancer : COSMICGALE 
CONAN: Copy Number AnalysisGALE 
Mutations and Diseases : HGMDGALE
Mutations and Diseases : intOGenGALE
Genomic VariantsGALE  GALE [DGVbeta]
dbVarGALE
ClinVarGALE
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM230350    606953   
MedgenGALE
GENETestsGALE
Disease Genetic AssociationGALE
Huge Navigator GALE [HugePedia]  GALE [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGALE
Homology/Alignments : Family Browser (UCSC)GALE
Phylogenetic Trees/Animal Genes : TreeFamGALE
Chemical/Protein Interactions : CTD2582
Chemical/Pharm GKB GenePA28531
Clinical trialGALE
Cancer Resource (Charite)ENSG00000117308
Other databases
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
CoreMineGALE
iHOPGALE
OncoSearchGALE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:47:41 CEST 2014

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