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GALK2 (galactokinase 2)

Identity

Alias_symbol (synonym)GK2
Other alias
HGNC (Hugo) GALK2
LocusID (NCBI) 2585
Atlas_Id 63680
Location 15q21.1  [Link to chromosome band 15q21]
Location_base_pair Starts at 49447956 and ends at 49622002 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GABPB1 (15q21.2) / GALK2 (15q21.1)GALK2 (15q21.1) / C15orf43 (15q21.1)GALK2 (15q21.1) / FAM214A (15q21.2)
GALK2 (15q21.1) / GOPC (6q22.1)PDIA3 (15q15.3) / GALK2 (15q21.1)USP8 (15q21.2) / GALK2 (15q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GALK2   4119
Cards
Entrez_Gene (NCBI)GALK2  2585  galactokinase 2
AliasesGK2
GeneCards (Weizmann)GALK2
Ensembl hg19 (Hinxton) [Gene_View]  chr15:49447956-49622002 [Contig_View]  GALK2 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr15:49447956-49622002 [Contig_View]  GALK2 [Vega]
TCGA cBioPortalGALK2
AceView (NCBI)GALK2
Genatlas (Paris)GALK2
WikiGenes2585
SOURCE (Princeton)GALK2
Genetics Home Reference (NIH)GALK2
Genomic and cartography
GoldenPath hg19 (UCSC)GALK2  -     chr15:49447956-49622002 +  15q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GALK2  -     15q21.1   [Description]    (hg38-Dec_2013)
EnsemblGALK2 - 15q21.1 [CytoView hg19]  GALK2 - 15q21.1 [CytoView hg38]
Mapping of homologs : NCBIGALK2 [Mapview hg19]  GALK2 [Mapview hg38]
OMIM137028   
Gene and transcription
Genbank (Entrez)AF461816 AK098049 AK301361 AK316440 AL832745
RefSeq transcript (Entrez)NM_001001556 NM_001289030 NM_001289031 NM_002044
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)GALK2
Cluster EST : UnigeneHs.738534 [ NCBI ]
CGAP (NCI)Hs.738534
Gene ExpressionGALK2 [ NCBI-GEO ]   GALK2 [ EBI - ARRAY_EXPRESS ]   GALK2 [ SEEK ]   GALK2 [ MEM ]
Gene Expression Viewer (FireBrowse)GALK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2585
GTEX Portal (Tissue expression)GALK2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01415   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01415  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01415
Splice isoforms : SwissVarQ01415
Catalytic activity : Enzyme2.7.1.157 [ Enzyme-Expasy ]   2.7.1.1572.7.1.157 [ IntEnz-EBI ]   2.7.1.157 [ BRENDA ]   2.7.1.157 [ KEGG ]   
PhosPhoSitePlusQ01415
Domaine pattern : Prosite (Expaxy)GALACTOKINASE (PS00106)    GHMP_KINASES_ATP (PS00627)   
Domains : Interpro (EBI)Galactokinase    Galactokinase_CS    GalKase_gal-bd    GHMP_kinase_C_dom    GHMP_kinase_N_dom    GHMP_knse_ATP-bd_CS    Mevalonate/galactokinase    Ribosomal_S5_D2-typ_fold    Ribosomal_S5_D2-typ_fold_subgr   
Domain families : Pfam (Sanger)GalKase_gal_bdg (PF10509)    GHMP_kinases_C (PF08544)    GHMP_kinases_N (PF00288)   
Domain families : Pfam (NCBI)pfam10509    pfam08544    pfam00288   
Conserved Domain (NCBI)GALK2
DMDM Disease mutations2585
Blocks (Seattle)GALK2
PDB (SRS)2A2C    2A2D   
PDB (PDBSum)2A2C    2A2D   
PDB (IMB)2A2C    2A2D   
PDB (RSDB)2A2C    2A2D   
Structural Biology KnowledgeBase2A2C    2A2D   
SCOP (Structural Classification of Proteins)2A2C    2A2D   
CATH (Classification of proteins structures)2A2C    2A2D   
SuperfamilyQ01415
Peptide AtlasQ01415
HPRD00657
IPIIPI00414287   IPI00791291   IPI01009376   IPI00186704   
Protein Interaction databases
DIP (DOE-UCLA)Q01415
IntAct (EBI)Q01415
BioGRIDGALK2
STRING (EMBL)GALK2
ZODIACGALK2
Ontologies - Pathways
QuickGOQ01415
Ontology : AmiGOgalactokinase activity  ATP binding  cytoplasm  carbohydrate metabolic process  galactose metabolic process  N-acetylgalactosamine kinase activity  carbohydrate phosphorylation  
Ontology : EGO-EBIgalactokinase activity  ATP binding  cytoplasm  carbohydrate metabolic process  galactose metabolic process  N-acetylgalactosamine kinase activity  carbohydrate phosphorylation  
Pathways : KEGGGalactose metabolism    Amino sugar and nucleotide sugar metabolism   
NDEx NetworkGALK2
Atlas of Cancer Signalling NetworkGALK2
Wikipedia pathwaysGALK2
Orthology - Evolution
OrthoDB2585
Phylogenetic Trees/Animal Genes : TreeFamGALK2
HOVERGENQ01415
HOGENOMQ01415
Homologs : HomoloGeneGALK2
Homology/Alignments : Family Browser (UCSC)GALK2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGALK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GALK2
dbVarGALK2
ClinVarGALK2
1000_GenomesGALK2 
Exome Variant ServerGALK2
ExAC (Exome Aggregation Consortium)GALK2 (select the gene name)
Genetic variants : HAPMAP2585
Genomic Variants (DGV)GALK2 [DGVbeta]
DECIPHER (Syndromes)15:49447956-49622002  
CONAN: Copy Number AnalysisGALK2 
Mutations
ICGC Data PortalGALK2 
TCGA Data PortalGALK2 
Broad Tumor PortalGALK2
OASIS PortalGALK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGALK2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGALK2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GALK2
DgiDB (Drug Gene Interaction Database)GALK2
DoCM (Curated mutations)GALK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GALK2 (select a term)
intoGenGALK2
Cancer3DGALK2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137028   
Orphanet
MedgenGALK2
Genetic Testing Registry GALK2
NextProtQ01415 [Medical]
TSGene2585
GENETestsGALK2
Huge Navigator GALK2 [HugePedia]
snp3D : Map Gene to Disease2585
BioCentury BCIQGALK2
ClinGenGALK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2585
Chemical/Pharm GKB GenePA28534
Clinical trialGALK2
Miscellaneous
canSAR (ICR)GALK2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGALK2
EVEXGALK2
GoPubMedGALK2
iHOPGALK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:05:44 CET 2017

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